Results 101 to 110 of about 2,932,686 (296)

A Gyroid TPMS-based machine learning framework for rapid prediction of cancellous bone mechanical properties

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionHigh-fidelity finite-element analysis of cancellous bone is computationally expensive, particularly when large parameter spaces must be explored. This study developed a rapid surrogate-modeling framework integrating parametric Gyroid modeling,
Xinzhe Chen, Jiqing Chen, Fengchong Lan
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Impact of stent graft geometry on hemodynamics in superior mesenteric artery reconstruction after fenestrated/branched endovascular aneurysm repair

open access: yesFrontiers in Bioengineering and Biotechnology
BackgroundDuring visceral artery reconstruction in fenestrated/branched endovascular aneurysm repair (F/B-EVAR), the superior mesenteric artery (SMA) plays a critical role in intestinal perfusion and often exhibits complex postoperative geometry. In this
ShuTing Gao   +7 more
doaj   +1 more source

Parametric energy modeling tool for climate dependent guidelines [PDF]

open access: yes, 2013
textThe purpose of this thesis is to develop a simple tool that can help designers and researchers obtain general guidelines for buildings in terms of energy usage and LCC.
Morales, Cristian Enrique
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Open Source HBIM and OpenAI: Review and New Analyses on LLMs Integration

open access: yesHeritage
This work concentrates on an experimental project for the integration of Large Language Models (LLMs) inside a Historic Building Information Modeling (HBIM) workflow.
Filippo Diara
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

A 3D Parameterized BIM-Modeling Method for Complex Engineering Structures in Building Construction Projects

open access: yesBuildings
The structural components of large-scale public construction projects are more complex than those of ordinary residential buildings, with irregular and diverse components, as well as a large number of repetitive structural elements, which increase the ...
Lijun Yang   +4 more
doaj   +1 more source

3D modeling for environmental informatics parametric manifold of an object under different viewing directions

open access: yes, 2017
3D modeling plays an important role in the field of computer vision and image processing. It provides a convenient tool set for many environmental informatics tasks, such as taxonomy and species identification.
Gao, Y, Zhang, X
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

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