Results 71 to 80 of about 161,142 (265)

New Numerical Solution for Two Parametric Surfaces Intersection Dragging Problem

International Journal of Analysis and Applications, 2021
The problem of intersecting two parametric surfaces has been one of the main technical challenges in computer-aided design, computer graphics, solid modeling, and geometrics.
Ramadhan A. M. Alsaidi
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Spatial Resolution of Attenuation Imaging

Archives of Acoustics, 2014
The attenuating properties of biological tissue are of great importance in ultrasonic examination even though its anatomical variability limits diagnostics effectiveness.
Ziemowit KLIMONDA, Jerzy LITNIEWSKI, Andrzej NOWICKI   +2 more
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

基于UG/OPEN API的蜗杆传动参数化系统开发

Jixie chuandong, 2008
A method to exploit worm gear and worm parametric system with UG/OPEN API was introduced.Under the VC environment,worm gear tooth contact strength and tooth root bending strength were checked,and a database system about worm gear and worm material and ...
周卿, 赵韩, 吴振华, 张建国
doaj  

Three-dimensional joint bright, gray, and black blood magnetic resonance imaging technique for multi-parametric imaging of carotid artery: A feasibility and repeatability study

Journal of Cardiovascular Magnetic Resonance
: Background: Multi-parametric imaging of the carotid artery enables quantitative characterization of vulnerable atherosclerotic plaques, which is crucial for preventing ischemic stroke.
Ning Xu, Shuo Chen, Ziming Xu, Zihan Ning, Shuwan Yu, Guimei Liu, Tao Wang, Yanbo Ma, Xiaomei Sun, Xiufeng Meng, Yazheng Chen, Jiachen Liu, Qinxin Wang, Huiyu Qiao, Xihai Zhao   +14 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Real Time Acceleration Tracking of Electro-Hydraulic Shake Tables Combining Inverse Compensation Technique and Neural-Based Adaptive Controller

IEEE Access, 2017
Electro-hydraulic shake table (EHST) is vital seismic testing equipment in earthquake engineering for the assessment of structures subject to dynamic vibration excitations.
Yu Tang, Zhencai Zhu, Gang Shen, Wenjuan Zhang   +3 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source