Results 11 to 20 of about 51,285 (216)

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth   +10 more
wiley   +1 more source

Cancer-associated retinopathy: an autoimmune retinopathy

open access: yesUniversa Medicina, 2016
Cancer-associated retinopathy (CAR) is a paraneoplastic syndrome most commonly associated with small-cell carcinoma of the lung, but also less frequently reported in patients with breast, endometrial, and other cancers. A paraneoplastic syndrome (PNS) is
Nurbuanto Tradjutrisno
doaj   +1 more source

Lung adenocarcinoma presenting with eosinophilic erythroderma associated with anti‐KRT6B antibodies: Case report

open access: yesJEADV Clinical Practice, 2023
Paraneoplastic erythroderma (PE) is a rare and potentially life‐threatening inflammatory condition associated with malignancy. PE may potentially develop due to antibodies produced against tumoral antigens that cross‐react with epidermal structures.
Nihan Erden   +11 more
doaj   +1 more source

Autoimmune Encephalitis: A Physician’s Guide to the Clinical Spectrum Diagnosis and Management

open access: yesBrain Sciences, 2022
The rapidly expanding spectrum of autoimmune encephalitis in the last fifteen years is largely due to ongoing discovery of many neuronal autoantibodies.
Arpan Patel   +4 more
doaj   +1 more source

Paraneoplastic Pemphigus

open access: yes, 2022
Paraneoplastic pemphigus is a rare but severe potentially fatal autoimmune disease characterized by severe stomatitis and a variety of cutaneous manifestations in association with an underlying neoplasia. Pulmonary involvement may also occur. The pathogenesis involves the production of autoantibodies against desmogleins, plakins and the protease ...
Poot, Angelique M.   +4 more
openaire   +2 more sources

Remitting Seronegative Symmetrical Synovitis with Pitting Oedema as the First Manifestation of an Adenocarcinoma of the Caecum

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2018
Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) is a rare syndrome that affects the elderly. Although the aetiology is not fully understood, it has been related to multiple diseases including cancer.
Edgar Pratas   +6 more
doaj   +1 more source

Paraneoplastic sacroiliitis

open access: yesBMJ Case Reports, 2023
A man in his early 70s presented with stiffness and aching in the shoulder and pelvic girdles. His C reactive protein level was elevated at 116 mg/L, leading to an initial diagnosis of polymyalgia rheumatica. Treatment with prednisone at 20 mg/day provided limited improvement and relapses recurred despite concomitant immunosuppressive agents. Extensive
Uri Arad, Charles Werren, Douglas White
openaire   +3 more sources

Rare case of upper urinary tract squamous cell carcinoma presenting with significant paraneoplastic syndrome

open access: yesUrology Annals, 2020
Squamous cell carcinoma of the upper urinary tract is a rare entity associated with rapidly progressive disease and poor outcomes. Here, we describe a case of a squamous cell carcinoma of the upper urinary tract associated with significant progression ...
Sandra S.Y. Kim   +5 more
doaj   +1 more source

Dermatomyositis: A Rare Presentation of Metastatic Prostate Cancer

open access: yesJournal of Scientific Innovation in Medicine, 2021
Background: Dermatomyositis (DM) is an idiopathic inflammatory myopathy with various cutaneous manifestations. There is a strong association between DM and malignancy with an estimated 5–7 fold increase in cancer incidence in DM patients compared to the ...
Iman Makki   +5 more
doaj   +1 more source

Comparison of commercial and in-house tissue-based and cell-based assays for the detection of autoantibodies targeting neuronal surface proteins: a prospective cohort study

open access: yesFrontiers in Immunology
IntroductionThe detection of antibodies targeting neuronal antigens is a keystone for the diagnosis of autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS).
David Goncalves   +17 more
doaj   +1 more source

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