Results 11 to 20 of about 62,191 (215)

Copine-4 Paraneoplastic Autoimmune Encephalitis. [PDF]

open access: yesAnn Clin Transl Neurol
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Fang MS   +12 more
europepmc   +2 more sources

Paraneoplastic Syndrome

open access: yes, 2020
Myenteric ganglionitis Inflammation of the myenteric plexus observed during paraneoplastic gastrointestinal motility disorders. Histopathology shows a dense T cell-lymphocytic and plasma cell infiltrate that is primarily confined to the myenteric ...
Caio, Giacomo   +10 more
core   +4 more sources

Paraneoplastic glomerular disease. Case study

open access: yes, 2022
The case of membranous nephropathy manifested in nephrotic syndrome in a patient, newly diagnosed with lung cancer, is reported. Brief data on the paraneoplastic glomerular disease are provided, the need for cancer screening in elderly patients with ...
Ekaterina S. Stolyarevich   +5 more
core   +1 more source

Diagnosis and treatment of paraneoplastic neurological disorders [PDF]

open access: yes, 2004
In about two thirds of cases, patients with paraneoplastic neurological disorders present to the neurologist without a known tumor. Due to the ongoing immune response, this tumor tends to stay biologically relatively benign, and therefore difficult to ...
Voltz, R., Graus, F.
core   +1 more source

N-methyl-D-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes [PDF]

open access: yes, 2010
Antibodies to the N-methyl-d-aspartate subtype of glutamate receptor have been associated with a newly-described encephalopathy that has been mainly identified in young females with ovarian tumours.
Irani, Sarosh R.   +27 more
core   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth   +10 more
wiley   +1 more source

Clinical approach to neurological paraneoplastic syndromes. [PDF]

open access: yesIntern Med J
Neurological paraneoplastic syndromes are immune‐mediated disorders. The diagnosis of paraneoplastic syndromes is often difficult because they are rare and the onset of symptoms usually precedes detection of the underlying malignancy.
Anderson NE.
europepmc   +2 more sources

Paraneoplastic Syndrome [PDF]

open access: yes, 2015
Rare and diagnostically challenging, paraneoplastic syndromes can appear months to years before detection of their underlying neoplasms and are associated with rapidly progressive neurologic deficits, including cochleovestibulopathy and death.
Matsuoka, Akihiro J   +3 more
core   +1 more source

Rare case of upper urinary tract squamous cell carcinoma presenting with significant paraneoplastic syndrome

open access: yesUrology Annals, 2020
Squamous cell carcinoma of the upper urinary tract is a rare entity associated with rapidly progressive disease and poor outcomes. Here, we describe a case of a squamous cell carcinoma of the upper urinary tract associated with significant progression ...
Sandra S.Y. Kim   +5 more
doaj   +1 more source

Dermatomyositis: A Rare Presentation of Metastatic Prostate Cancer

open access: yesJournal of Scientific Innovation in Medicine, 2021
Background: Dermatomyositis (DM) is an idiopathic inflammatory myopathy with various cutaneous manifestations. There is a strong association between DM and malignancy with an estimated 5–7 fold increase in cancer incidence in DM patients compared to the ...
Iman Makki   +5 more
doaj   +1 more source

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