Results 11 to 20 of about 49,678 (216)

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth, Bruce Robinson, Valentina Boni, Daniel S.W. Tan, Caroline McCoach, Erminia Massarelli, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Vivek Subbiah   +10 more
wiley   +1 more source

Lung adenocarcinoma presenting with eosinophilic erythroderma associated with anti‐KRT6B antibodies: Case report

JEADV Clinical Practice, 2023
Paraneoplastic erythroderma (PE) is a rare and potentially life‐threatening inflammatory condition associated with malignancy. PE may potentially develop due to antibodies produced against tumoral antigens that cross‐react with epidermal structures.
Nihan Erden, Saba Khoshbakht, Arda Yaycioglu, Ali Kizilirmak, Özgecan Kayalar, Cüyan Demirkesen, Ibrahim Kulaç, Nazlı Ezgi Özkan Küçük, Nurhan Ozlu, Thomas Ruzicka, Andreas Wollenberg, Seçil Vural   +11 more
doaj   +1 more source

Autoimmune Encephalitis: A Physician’s Guide to the Clinical Spectrum Diagnosis and Management

Brain Sciences, 2022
The rapidly expanding spectrum of autoimmune encephalitis in the last fifteen years is largely due to ongoing discovery of many neuronal autoantibodies.
Arpan Patel, Yue Meng, Amanda Najjar, Fred Lado, Souhel Najjar   +4 more
doaj   +1 more source

Remitting Seronegative Symmetrical Synovitis with Pitting Oedema as the First Manifestation of an Adenocarcinoma of the Caecum

European Journal of Case Reports in Internal Medicine, 2018
Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) is a rare syndrome that affects the elderly. Although the aetiology is not fully understood, it has been related to multiple diseases including cancer.
Edgar Pratas, João Carvalho, Isabel Domingues, João Fonseca, Teresa Carvalho, Gabriela Sousa, Manuel Teixeira Veríssimo   +6 more
doaj   +1 more source

Dermatomyositis: A Rare Presentation of Metastatic Prostate Cancer

Journal of Scientific Innovation in Medicine, 2021
Background: Dermatomyositis (DM) is an idiopathic inflammatory myopathy with various cutaneous manifestations. There is a strong association between DM and malignancy with an estimated 5–7 fold increase in cancer incidence in DM patients compared to the ...
Iman Makki, Binbin Zheng-Lin, Clare Bryce, Sadhna Ahuja, Sridevi Rajeeve, Vaibhav Patel   +5 more
doaj   +1 more source

Rare case of upper urinary tract squamous cell carcinoma presenting with significant paraneoplastic syndrome

Urology Annals, 2020
Squamous cell carcinoma of the upper urinary tract is a rare entity associated with rapidly progressive disease and poor outcomes. Here, we describe a case of a squamous cell carcinoma of the upper urinary tract associated with significant progression ...
Sandra S.Y. Kim, Ricardo A Rendon, Myuran Thana, Lori Wood, Cheng Wang, Ross J Mason   +5 more
doaj   +1 more source

Seronegative Paraneoplastic Opsoclonus–Myoclonus–Ataxia Syndrome Secondary to Low Volume Endocrine-Sensitive Malignancy of Likely Breast Origin

Current Oncology
A 51-year-old female presented to the emergency department with vertigo, visual disturbances, involuntary rapid repetitive eye movements, incoordination, and imbalance.
Geraint Berger, Caitlin Jackson-Tarlton, Daniel Rayson, Alexander Silver, Mark Walsh, Ashley Drohan   +5 more
doaj   +1 more source

AQP4‐IgG positive paraneoplastic NMOSD: A case report and review

Brain and Behavior, 2021
Introduction Neuromyelitis optica spectrum disorder (NMOSD; also known as Devic syndrome) is a clinical syndrome of central nervous system characterized by immune mediated attacks of acute optic neuritis and myelitis. Paraneoplastic neurological syndrome
Manqiu Ding, Yue Lang, Li Cui
doaj   +1 more source

A rare clinical presentation of Hodgkin's disease

Journal of Applied Hematology, 2022
Hodgkin's disease or Hodgkin's lymphoma (HL) is a hematolymphoid neoplasm of B-cell lineage that has unique histologic, immunophenotypic, and clinical features.
Prashanth Parameswaran, Dilip Harindran Vallathol, Narayanankutty Warrier, Sajna V Kutty   +3 more
doaj   +1 more source

Gastroesophageal reflux disease and paraneoplastic neurological syndrome associated with long‐term survival in limited stage small‐cell lung cancer

Thoracic Cancer, 2022
Introduction Patients with small‐cell lung cancer (SCLC) have a very poor prognosis. However, a subset of SCLC achieves long‐term survival. The objective of this study was to investigate factors and pattern of long‐term survival in patients with limited ...
Vinicius Ernani, Lin Du, Helen J. Ross, Joanne E. Yi, Jason A. Wampfler, Steven E. Schild, Hao Xie, Karen L. Swanson, Henry D. Tazelaar, Ping Yang   +9 more
doaj   +1 more source