Results 21 to 30 of about 62,191 (215)

Immune checkpoint inhibitor neurotoxicity: long-term outcomes with focus on 1-year neurological sequelae

Journal for ImmunoTherapy of Cancer
Background Data on the long-term course of neurological immune-related adverse events (n-irAEs) are limited by the size of studies as well as short and heterogeneous follow-up durations.
Dimitri Psimaras, Bastien Joubert, Geraldine Picard, Jerome Honnorat, Jerome Aupy, Giovanni Corazza, Véronique Bourg, Marie Rafiq, Macarena Villagrán-García, Antonio Farina, Marie Benaiteau, Amna Abichou-Klich, Tifanie Alberto, Aurélien Maureille   +13 more
doaj   +1 more source

Comparison of commercial and in-house tissue-based and cell-based assays for the detection of autoantibodies targeting neuronal surface proteins: a prospective cohort study

Frontiers in Immunology
IntroductionThe detection of antibodies targeting neuronal antigens is a keystone for the diagnosis of autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS).
David Goncalves, Marie Benaiteau, Marie Benaiteau, Véronique Rogemond, Véronique Rogemond, Sterenn Closs, Sterenn Closs, Anne-Laurie Pinto, Anne-Laurie Pinto, Maroua Dhairi, Maroua Dhairi, Marine Villard, Marine Villard, Géraldine Picard, Géraldine Picard, Nicole Fabien, Jérôme Honnorat, Jérôme Honnorat   +17 more
doaj   +1 more source

AQP4‐IgG positive paraneoplastic NMOSD: A case report and review

Brain and Behavior, 2021
Introduction Neuromyelitis optica spectrum disorder (NMOSD; also known as Devic syndrome) is a clinical syndrome of central nervous system characterized by immune mediated attacks of acute optic neuritis and myelitis. Paraneoplastic neurological syndrome
Manqiu Ding, Yue Lang, Li Cui
doaj   +1 more source

Posterior Scleritis as a Paraneoplastic Syndrome in Colon Cancer: A Case Report

, 2020
This study presents a rare case of unilateral posterior scleritis as an ophthalmic manifestation of a paraneoplastic syndrome. A 61-year-old man presented to our department complaining of gradual worsening of vision in his left eye.
Dimitrios Kalogeropoulos, Konstantinos Katsikatsos, Chris Kalogeropoulos, Michail Mitsis   +3 more
core   +1 more source

Endocrine abnormality in paraneoplastic syndrome [PDF]

, 2022
Paraneoplastic syndromes denote rare but notable phenomena caused by the tumour mediated release of bioactive substances. Peptide and non-peptide hormone causes are explored with a particular focus on pathogenesis, symptoms, diagnosis and treatment ...
Onyema, Michael C., Dimitriadis, Georgios K., Drakou , Eftychia E.   +2 more
core   +1 more source

Gastroesophageal reflux disease and paraneoplastic neurological syndrome associated with long‐term survival in limited stage small‐cell lung cancer

Thoracic Cancer, 2022
Introduction Patients with small‐cell lung cancer (SCLC) have a very poor prognosis. However, a subset of SCLC achieves long‐term survival. The objective of this study was to investigate factors and pattern of long‐term survival in patients with limited ...
Vinicius Ernani, Lin Du, Helen J. Ross, Joanne E. Yi, Jason A. Wampfler, Steven E. Schild, Hao Xie, Karen L. Swanson, Henry D. Tazelaar, Ping Yang   +9 more
doaj   +1 more source

A rare clinical presentation of Hodgkin's disease

Journal of Applied Hematology, 2022
Hodgkin's disease or Hodgkin's lymphoma (HL) is a hematolymphoid neoplasm of B-cell lineage that has unique histologic, immunophenotypic, and clinical features.
Prashanth Parameswaran, Dilip Harindran Vallathol, Narayanankutty Warrier, Sajna V Kutty   +3 more
doaj   +1 more source

Seronegative Paraneoplastic Opsoclonus–Myoclonus–Ataxia Syndrome Secondary to Low Volume Endocrine-Sensitive Malignancy of Likely Breast Origin

Current Oncology
A 51-year-old female presented to the emergency department with vertigo, visual disturbances, involuntary rapid repetitive eye movements, incoordination, and imbalance.
Geraint Berger, Caitlin Jackson-Tarlton, Daniel Rayson, Alexander Silver, Mark Walsh, Ashley Drohan   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Longitudinal, Observational Analysis of Neuronal Injury Biomarkers in a Case Report of a Patient With Paraneoplastic Anti-CRMP5 Antibody-Associated Transverse Myelitis

Frontiers in Neurology, 2021
Biomarkers are needed to guide therapeutic decision making in autoimmune and paraneoplastic neurologic disorders. Here, we describe a case of paraneoplastic collapsing response-mediator protein-5 (CRMP5)-associated transverse myelitis (TM) where plasma ...
Christopher Mizenko, Jeffrey L. Bennett, Jeffrey L. Bennett, Gregory Owens, Timothy L. Vollmer, Amanda L. Piquet   +5 more
doaj   +1 more source