Results 21 to 30 of about 493,772 (158)

Paraneoplastic Diseases of the Central Nervous System [version 1; peer review: 2 approved]

F1000Research, 2020
Paraneoplastic neurological syndromes are nonmetastatic complications of malignancy secondary to immune-mediated neuronal dysfunction or death. Pathogenesis may occur from cell surface binding of antineuronal antibodies leading to dysfunction of the ...
Jonathan Galli, John Greenlee
doaj   +1 more source

Cerebellar long-term depression and auto-immune target of auto-antibodies: the concept of LTDpathies

Molecular Biomedicine, 2021
There is general agreement that auto-antibodies against ion channels and synaptic machinery proteins can induce limbic encephalitis. In immune-mediated cerebellar ataxias (IMCAs), various synaptic proteins, such as GAD65, voltage-gated Ca channel (VGCC),
Hiroshi Mitoma, Jerome Honnorat, Kazuhiko Yamaguchi, Mario Manto   +3 more
doaj   +1 more source

Immune checkpoint inhibitor neurotoxicity: long-term outcomes with focus on 1-year neurological sequelae

Journal for ImmunoTherapy of Cancer
Background Data on the long-term course of neurological immune-related adverse events (n-irAEs) are limited by the size of studies as well as short and heterogeneous follow-up durations.
Dimitri Psimaras, Bastien Joubert, Geraldine Picard, Jerome Honnorat, Jerome Aupy, Giovanni Corazza, Véronique Bourg, Marie Rafiq, Macarena Villagrán-García, Antonio Farina, Marie Benaiteau, Amna Abichou-Klich, Tifanie Alberto, Aurélien Maureille   +13 more
doaj   +1 more source

Antibodies to TRIM46 are associated with paraneoplastic neurological syndromes. [PDF]

Ann Clin Transl Neurol, 2017
Paraneoplastic neurological syndromes (PNS) are often characterized by the presence of antineuronal antibodies in patient serum or cerebrospinal fluid.
van Coevorden-Hameete MH, van Beuningen SFB, Perrenoud M, Will LM, Hulsenboom E, Demonet JF, Sabater L, Kros JM, Verschuuren JJGM, Titulaer MJ, de Graaff E, Sillevis Smitt PAE, Hoogenraad CC.   +12 more
europepmc   +3 more sources

Comparison of commercial and in-house tissue-based and cell-based assays for the detection of autoantibodies targeting neuronal surface proteins: a prospective cohort study

Frontiers in Immunology
IntroductionThe detection of antibodies targeting neuronal antigens is a keystone for the diagnosis of autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS).
David Goncalves, Marie Benaiteau, Marie Benaiteau, Véronique Rogemond, Véronique Rogemond, Sterenn Closs, Sterenn Closs, Anne-Laurie Pinto, Anne-Laurie Pinto, Maroua Dhairi, Maroua Dhairi, Marine Villard, Marine Villard, Géraldine Picard, Géraldine Picard, Nicole Fabien, Jérôme Honnorat, Jérôme Honnorat   +17 more
doaj   +1 more source

Paraneoplastic antigens as biomarkers for early diagnosis of ovarian cancer

Gynecologic Oncology Reports, 2017
Paraneoplastic syndromes are a group of rare disorders that can be triggered by an abnormal immune response to proteins from tumors of the lung, ovary, lymphatics, or breast. Paraneoplastic clinical syndromes affect
Madhumita Chatterjee, Laura C. Hurley, Michael A. Tainsky   +2 more
doaj   +1 more source

Neurological paraneoplastic syndromes.

, 1997
Paraneoplastic neurological syndromes are uncommon, however, their diagnosis is of major practical importance. The identification of antibodies in the serum or cerebrospinal fluid in central nervous system paraneoplastic syndromes confirms the clinical ...
Grant, R, Nath, U
core   +1 more source

Psychiatric manifestations of paraneoplastic syndromes

European Psychiatry, 2022
Introduction Paraneoplastic syndromes (PS) result from indirect effects of neoplasms. In 50% of the cases the symptoms precede the diagnosis and run independently.
M. Lemos, A. Lourenço, M. Ribeiro
doaj   +1 more source

A rare case of concomitant Lambert–Eaton myasthenic syndrome and syndrome of inappropriate antidiuretic hormone secretion in a patient with small cell lung carcinoma

Respiratory Medicine Case Reports, 2023
Small cell lung carcinoma (SCLC) is a neuroendocrine carcinoma with a poor prognosis and is a common cause of paraneoplastic syndromes. Paraneoplastic syndromes are characterized by neurological and endocrinological problems in patients with malignancy ...
Yasuharu Oda, Hironobu Tsubouchi, Nobuyuki Ishii, Aya Kitamura, Eiji Moriyama, Eriko Mitsutome, Katsuya Sakai, Kazutaka Shiomi, Shigehisa Yanagi, Taiga Miyazaki   +9 more
doaj   +1 more source

Autonomic paraneoplastic neurological syndromes

, 2007
Autonomic paraneoplastic neurological syndromes (PNS) typically present as chronic gastrointestinal pseudo-obstruction or orthostatic hypotension and usually occur in association with other PNS rather than in isolation.
HART IK, RICEVUTI, GIOVANNI, FERRARI D, LORUSSO L, NGONGA GK, GASPARETTO C   +5 more
core   +1 more source