Results 21 to 30 of about 8,347 (150)

Paraneoplastic Diseases of the Central Nervous System [version 1; peer review: 2 approved]

F1000Research, 2020
Paraneoplastic neurological syndromes are nonmetastatic complications of malignancy secondary to immune-mediated neuronal dysfunction or death. Pathogenesis may occur from cell surface binding of antineuronal antibodies leading to dysfunction of the ...
Jonathan Galli, John Greenlee
doaj   +1 more source

Cerebellar long-term depression and auto-immune target of auto-antibodies: the concept of LTDpathies

Molecular Biomedicine, 2021
There is general agreement that auto-antibodies against ion channels and synaptic machinery proteins can induce limbic encephalitis. In immune-mediated cerebellar ataxias (IMCAs), various synaptic proteins, such as GAD65, voltage-gated Ca channel (VGCC),
Hiroshi Mitoma, Jerome Honnorat, Kazuhiko Yamaguchi, Mario Manto   +3 more
doaj   +1 more source

Update on neurological paraneoplastic syndromes [PDF]

Current Opinion in Oncology, 2015
To provide an update on paraneoplastic neurologic syndromes (PNS), the involved tumors, and types of immune responses.PNS are a diverse group of syndromes that may present as a relatively isolated syndrome such as predominant cerebellar degeneration or limbic encephalitis, or with more complex phenotypes such as diffuse encephalomyelitis that affects ...
Romana, Höftberger, Myrna R, Rosenfeld, Josep, Dalmau   +2 more
openaire   +2 more sources

Paraneoplastic endocrine-metabolic syndromes

Italian Journal of Medicine, 2013
BACKGROUND The paraneoplastic syndromes (PS) are characterized by the presence of biochemical alterations, signs and symptoms expressive of cancer distance action into the patient’s organism.
Marco Grandi, Carla Sacchetti, Stefano Pederzoli, Cinzia Torri, Ilaria Sgarbi, Giovanni Partesotti, Massimiliano Nicolini, Chiara Casarini, Elena Romagnani, Chiara Benatti, Federica Vecchi, Claudio Gollini, Bruno Manni, Giacinto Sirotti, Maria Ernesta Leone, Rita Pasqualini, Antonio Pedrazzi   +16 more
doaj   +1 more source

Comparison of commercial and in-house tissue-based and cell-based assays for the detection of autoantibodies targeting neuronal surface proteins: a prospective cohort study

Frontiers in Immunology
IntroductionThe detection of antibodies targeting neuronal antigens is a keystone for the diagnosis of autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS).
David Goncalves, Marie Benaiteau, Marie Benaiteau, Véronique Rogemond, Véronique Rogemond, Sterenn Closs, Sterenn Closs, Anne-Laurie Pinto, Anne-Laurie Pinto, Maroua Dhairi, Maroua Dhairi, Marine Villard, Marine Villard, Géraldine Picard, Géraldine Picard, Nicole Fabien, Jérôme Honnorat, Jérôme Honnorat   +17 more
doaj   +1 more source

Paraneoplastic antigens as biomarkers for early diagnosis of ovarian cancer

Gynecologic Oncology Reports, 2017
Paraneoplastic syndromes are a group of rare disorders that can be triggered by an abnormal immune response to proteins from tumors of the lung, ovary, lymphatics, or breast. Paraneoplastic clinical syndromes affect
Madhumita Chatterjee, Laura C. Hurley, Michael A. Tainsky   +2 more
doaj   +1 more source

Psychiatric manifestations of paraneoplastic syndromes

European Psychiatry, 2022
Introduction Paraneoplastic syndromes (PS) result from indirect effects of neoplasms. In 50% of the cases the symptoms precede the diagnosis and run independently.
M. Lemos, A. Lourenço, M. Ribeiro
doaj   +1 more source

A rare case of concomitant Lambert–Eaton myasthenic syndrome and syndrome of inappropriate antidiuretic hormone secretion in a patient with small cell lung carcinoma

Respiratory Medicine Case Reports, 2023
Small cell lung carcinoma (SCLC) is a neuroendocrine carcinoma with a poor prognosis and is a common cause of paraneoplastic syndromes. Paraneoplastic syndromes are characterized by neurological and endocrinological problems in patients with malignancy ...
Yasuharu Oda, Hironobu Tsubouchi, Nobuyuki Ishii, Aya Kitamura, Eiji Moriyama, Eriko Mitsutome, Katsuya Sakai, Kazutaka Shiomi, Shigehisa Yanagi, Taiga Miyazaki   +9 more
doaj   +1 more source

Paraneoplastic syndromes associated with tumors of the digestive system

Universidad Médica Pinareña, 2021
Introduction: paraneoplastic syndromes are sets of signs and symptoms affecting cancer patients, which do not depend directly on the tumor. Objective: to describe paraneoplastic syndromes associated with digestive system tumors.
Roxana Vitón-Moreno, Alain Areces-López   +1 more
doaj  

Autoimmunity in Paraneoplastic Neurological Syndromes

Brain Pathology, 1999
In patients with Paraneoplastic Neurological Disorders, the researcher detected several autoanti‐bodies reacting with neuronal antigens and tumors; their characteristics supported the hypothesis that autoimmunity plays a part in these diseases and gave impetus to the study of these neurological disorders.The relationship between detection of anti ...
Giometto B, Taraloto B, Graus F
openaire   +4 more sources