Results 131 to 140 of about 8,175 (178)

Paraneoplastic Syndromes of the Nervous System

cclm, 2000
Abstract Paraneoplastic syndromes affecting the nervous system are unique among immune-mediated disorders in that the trigger of the immune response is known: tumor expression of proteins normally restricted to neurons (or other immunoprivileged sites, such as testis) but ectopically expressed in some cancers results in an immunological ...
J B, Posner, J O, Dalmau
openaire   +2 more sources

Paraneoplastic nervous system syndromes

Current Opinion in Oncology, 1996
Recent progress in the understanding of the paraneoplastic neurologic syndromes has included further deliniation of the clinical syndromes and their treatment, attempts at standardization of the diagnostic nomenclature, investigations of pathogenetic mechanisms, and molecular characterization of the paraneoplastic antigens with implications as to their
openaire   +2 more sources

Autoantibody synthesis in the central nervous system of patients with paraneoplastic syndromes

Neurology, 1990
We measured the activity of 2 highly specific autoantibodies (anti-Yo associated with paraneoplastic cerebellar degeneration and anti-Hu associated with paraneoplastic sensory neuronopathy-encephalomyelitis) in simultaneously procured samples of serum and CSF of 18 patients.
H F, Furneaux, L, Reich, J B, Posner
openaire   +2 more sources

Paraneoplastic Syndromes of the Nervous System

2003
In patients with cancer the development of neurological symptoms usually represents metastatic involvement of the nervous system, or complications secondary to coagulopathy, infection, metabolic and nutritional deficits, and toxic effects of cancer therapy (1).
Myrna R. Rosenfeld, Josep Dalmau
openaire   +1 more source

[Paraneoplastic syndromes of the central nervous system].

La Clinica terapeutica, 2000
Paraneoplastic syndromes of central nervous system are rare neurologic syndromes caused by cancer but not secondary to metastases. The physiopathologic mechanisms underlying these syndromes are still under debate. We report the biological and clinical features of the most frequent paraneoplastic syndromes involving the central nervous system.
Silvestris N, Lucarelli A, Scaringella P, Di Ciaula A, Ambrosini S, Fata L   +5 more
openaire   +2 more sources

Paraneoplastic Syndromes of the Nervous System as Complications of Cancer

2017
In patients with cancer the development of neurological symptoms usually represents metastatic involvement of the nervous system or complications secondary to coagulopathy, infection, metabolic and nutritional deficits, and toxic effects of cancer therapy.
Myrna R. Rosenfeld, Josep Dalmau
openaire   +1 more source

Autonomic nervous system involvement in autoimmune encephalitis and paraneoplastic neurological syndromes

Revue Neurologique
In autoimmune neurological diseases, the autonomic nervous system can be the primary target of autoimmunity (e.g. autoimmune autonomic ganglionopathy), or, more frequently, be damaged together with other areas of the nervous system (e.g. Guillain-Barré syndrome).
M, Villagrán-García, A, Farina, L, Campetella, J, Arzalluz-Luque, J, Honnorat   +4 more
openaire   +2 more sources

Small Lymphocytic Lymphoma Presenting As a Paraneoplastic Syndrome With Acute Central Nervous System Demyelination

Clinical Lymphoma Myeloma and Leukemia, 2014
Chronic lymphocytic leukemia (CLL)/small lymphocytic lym-phoma (SLL) is a mature B-cell neoplasm characterized by accu-mulation of functionally incompetent clonal lymphocytes with thesame morphologic and immunophenotypic features. CLL and SLLhave the same cellular basis but SLL lacks significant peripheralblood (PB) lymphocytosis. CLL is the most common
Nicholas DeVito, Kit Mui, Yasir Jassam, Lynne Taylor, Monika Pilichowska, Furha Cossor   +5 more
openaire   +2 more sources

Paraneoplastic syndromes affecting the nervous system.

Seminars in oncology, 1997
Paraneoplastic syndromes can affect virtually any portion of the nervous system. Most paraneoplastic syndromes are believed to be caused by an autoimmune reaction to an "onconeural" antigen shared by the cancer and the nervous system. The immune reaction may retard growth of the cancer, but it also damages the nervous system.
J O, Dalmau, J B, Posner
openaire   +1 more source

Paraneoplastic Syndromes of the Central Nervous System

1984
The term paraneoplastic syndrome (PNS) includes muscular, peripheral and central nervous disorders arising in relation to malignancies, but resulting neither from direct infiltration by malignancies nor establishment of metastases. On the contrary, they are regarded as indirect sequelae.
openaire   +1 more source