Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in rats
Paraneoplastic neurological syndromes arise from autoimmune reactions against nervous system antigens due to a maladaptive immune response to a peripheral cancer.
Laurent Martin +19 more
doaj +1 more source
PurposeParaneoplastic neurological syndromes associated with autoantibodies are rare diseases that cause abnormal manifestations of the nervous system.
Sizhu Gong +5 more
doaj +1 more source
‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 2: Anti-PKC-gamma, anti-GluR-delta2, anti-Ca/ARHGAP26 and anti-VGCC [PDF]
Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis.
Jarius, Sven, Wildemann, Brigitte
core +1 more source
Vascular Supply of Laryngeal Paragangliomas: Case Report and Systematic Review
ABSTRACT Objective Laryngeal paragangliomas are rare, highly vascularized, neuroendocrine tumors. Although surgical resection of these vascular neoplasms is associated with a known risk of significant hemorrhage, the vascular supply of laryngeal paragangliomas has been poorly characterized. Data Sources MEDLINE Ovid, Embase, Scopus, and Google Scholar.
Jane Y. Tong +3 more
wiley +1 more source
Anti-Ma2 Antibody-Associated Paraneoplastic Neurological Syndromes: A Pilot Study
Paraneoplastic neurologic syndromes (PNSs) are a heterogeneous group of disorders caused by the remote effects of cancer with immune-mediated pathogenesis.
Yi Guo +5 more
doaj +1 more source
Exploring the interdependencies of research funders in the UK [PDF]
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P +13 more
core +1 more source
The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu +2 more
wiley +1 more source
Leptomeningeal Carcinomatosis: A Clinical Dilemma in Neuroendocrine Neoplasms
Central nervous system (CNS) involvement by paraneoplastic syndromes, brain metastases, or leptomeningeal carcinomatosis (LC) in patients with neuroendocrine neoplasms (NEN) has only been described in individual case reports.
Leonidas Apostolidis +4 more
doaj +1 more source
Neurological Peculiarities of POEMS Syndrome: Experience From a Brazilian University Center
ABSTRACT Aim Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is a rare paraneoplastic syndrome associated with significant neurologic morbidity. Better understanding of the manifestations of this disease is crucial to early diagnosis and improvement of prognosis.
Renan Fabri Rosenstein +5 more
wiley +1 more source
Multiple cranial neuropathies as a manifestation of paraneoplastic syndrome in thymoma
Neurological symptoms could be a manifestation of cancer both with direct involvement of the nervous system (tumor invasion, metastasis, compression of nerve tissue by neoplasm) and its mediated damage in patients with paraneoplastic syndromes ...
G. R. Ramazanov +5 more
doaj +1 more source

