Results 11 to 20 of about 6,578 (194)

Tropical spastic paraparesis in Northeastern Brazil [PDF]

Arquivos de Neuro-Psiquiatria, 1989
Ten possible cases of tropical spastic paraparesis (TSP) in Northeastern Brazil (Ceará) are presented. They show the typical symptoms and signs of TSP consisting of weakness of the lower limbs, spastic gait, hiperreflexia, bladder dysfunction and ...
C. M. de Castro Costa, M. R. Salgueiro, H. Carton, O. C. do Vale, A. M. de Arruda   +4 more
doaj   +4 more sources

Early-Onset HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis [PDF]

Pathogens, 2020
Background: Vertical transmission of HTLV-1 could lead to the early development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). This significantly affects quality of life and increases morbimortality.
Alvaro Schwalb, Valeria Pérez-Muto, Rodrigo Cachay, Martín Tipismana, Carolina Álvarez, Fernando Mejía, Elsa González-Lagos, Eduardo Gotuzzo   +7 more
doaj   +4 more sources

Brazilian studies on tropical spastic paraparesis: a meta-analysis [PDF]

Arquivos de Neuro-Psiquiatria, 1994
Tropical spastic paraparesis (TSP) is a chronic progressive myelopathy and in most of the cases has a retroviral (HTLV-1) etiology, when it is denominated HTLV-1 associated-mielopathy (HAM/TSP).
C.M. de Castro Costa, H. Carton, P. Goubau, J.A.C. D'Almeida   +3 more
doaj   +4 more sources

Clinical Characteristics of Parkinsonism in HTLV-1-Associated Myelopathy. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Dozono M, Nozuma S, Hirakata S, Yoshida T, Kodama D, Tanaka M, Matsuura E, Kubota R, Takashima H.   +8 more
europepmc   +2 more sources

Cerebrospinal Fluid From Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) With Rapid Evolution Affects Mitochondrial DNA Transcription and Network Organization in Human Glioblastoma Cells. [PDF]

J Med Virol
ABSTRACT Human T‐lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurodegenerative disease affecting motor and sensory functions. While alterations in cerebrospinal fluid (CSF) have been used to identify disease biomarkers, the effects of such modified CSF on CNS cells remain unexplored.
Gomes YCP, Bongers A, Jeannin P, Vicente ACP, Gessain A, Afonso PV, Espindola OM.   +6 more
europepmc   +2 more sources

Gut Microbiome Dysbiosis is Associated With Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection and Disease Progression to HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Cross-Sectional Study. [PDF]

Smart Med
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Fernandes LA, de Souza AO, Nukui Y, Marcusso RM, de Oliveira ACP, Casseb J, Clissa PB, Villas-Boas SG, Sanabani SS.   +8 more
europepmc   +2 more sources

Human T-Lymphotropic Virus Type 1-Associated Myelopathy With Autoimmune Cholangiopathy: An Unusual Immune Conundrum in a Young Patient. [PDF]

Case Rep Infect Dis
Human​ T‐lymphotropic virus type 1 (HTLV‐1), the first oncogenic retrovirus discovered in humans, is primarily associated with two disease entities: adult T cell leukemia‐lymphoma and HTLV‐1‐associated myelopathy‐tropical spastic paresis. HTLV‐1 has also been implicated in the pathogenesis of various autoimmune rheumatic diseases, and its association ...
Saad A, Jadoon Y, Sabir R.
europepmc   +2 more sources

Physiotherapy Methods Applied in the Prevention of Functional Loss Associated with Human T-Lymphotropic Virus 1 Infection: An Overview

Infectious Disease Reports, 2023
To achieve the objective of this study, we conducted a narrative review on physical therapeutic modalities applied to prevent functional losses associated with human T-lymphotropic virus 1 (HTLV-1) infections to promote health education and viable and ...
Izabela Mendonça de Assis, Bianca Callegari, Maisa Silva de Sousa   +2 more
doaj   +1 more source

Strengthening awareness and response to HTLV-1 infection in Africa: A neglected threat to blood safety and public health. [PDF]

Hemasphere
HemaSphere, Volume 9, Issue 10, October 2025.
Twizere JC, Rosadas C, Kidiga M, Djalo F, Murphy EL, Mouinga-Ondeme A, Vermeulen M, Morrell L, Diop S, Maseko S, Sebulime P, Agbleke AA, Fundisi B, Umumararungu E, Watber P, Hlela C, Nhavene E, Chidarikire T, Hermine O, Gessain A.   +19 more
europepmc   +2 more sources

High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. [PDF]

, 2015
BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL).
A Gessain, A Gessain, AH Smith, AM Vine, CR Bangham, D Weycker, E Gotuzzo, EL Murphy, F Okada, Graham P Taylor, H Kawai, H Merle, H Nakamura, IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, J Crofton, JR Orland, K Nishioka, L Einsiedel, L Einsiedel, L Einsiedel, L LaGrenade, M Nagai, M Nakagawa, M Osame, M Sugimoto, M Sugimoto, MA Demontis, MG Flynn, OS Morgan, PJ McShane, S Mita, S Mori, Shohreh Honarbakhsh, T Arakaki, T Kondo, T Matsuda, T Yamashiro, W Matsuyama   +37 more
core   +1 more source