Results 31 to 40 of about 4,843 (183)

Clinical pathophysiology of human T-lymphotropic virus-type1-associated myelopathy/tropical spastic paraparesis

Frontiers in Microbiology, 2012
Human T-lymphotropic virus type 1 (HTLV-1), a human retrovirus, is the causative agent of a progressive neurological disease termed HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Yoshihisa eYamano, Tomoo eSato
doaj   +2 more sources

Morbidity and Mortality Among People Living With HTLV-1: A 30-Year Retrospective Analysis in a Brazilian Cohort. [PDF]

J Med Virol
ABSTRACT HTLV‐1 infection is a chronic condition associated with the development of malignancies, inflammatory, and neurological disorders. In this study, the causes of hospitalization and mortality were assessed in a cohort of 508 individuals living with HTLV‐1 followed over a 30‐year period. Overall mortality was 8.5% in this population and increased
Neves ES, Espíndola OM, Oliveira RVC, Leite ACCB, Lima MASD, Silva MTT, Osellame R, Guimarães PAP, Batista RV, Oliveira ALA, Araújo AQC.   +10 more
europepmc   +2 more sources

Proprioceptive neuromuscular facilitation in HTLV-I-associated myelopathy/tropical spastic paraparesis

Revista da Sociedade Brasileira de Medicina Tropical, 2014
Introduction: Human T cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) can impact the independence and motricity of patients.
Vera Lúcia Santos de Britto, Rosalie Correa, Maurice Borges Vincent   +2 more
doaj   +2 more sources

Clinical Characteristics of Parkinsonism in HTLV-1-Associated Myelopathy. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Dozono M, Nozuma S, Hirakata S, Yoshida T, Kodama D, Tanaka M, Matsuura E, Kubota R, Takashima H.   +8 more
europepmc   +2 more sources

The Barriers of Coping with HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Content Analysis Study [PDF]

Journal of Evidence-Based Care, 2023
Background: HTLV-1-associated myelopathy is associated with constant stress, so it is very important to cope with this disease. To improve the coping of patients with this disease, it is necessary to deeply identify its barriers.Aim: The present study ...
Malihe Davoudi, Reza Boostani, Zahra Sadat Manzari   +2 more
doaj   +1 more source

Tropical spastic paraparesis / HTLV-associated myelopathy (TSP/HAM). Case reports in Colombian pacific coast

Revista de la Facultad de Ciencias de la Salud, 2013
Hospital-ship San Raffael of the Italian-Colombian Foundation of Monte Tabor develops a social and humanitarian function in the departments of Colombian pacific coast under the support of the Facultad de Ciencias de la Salud of University del Cauca.
Alonso Arturo Ruíz-Perea, Luis Eduardo Ramírez-Bejarano   +1 more
doaj   +3 more sources

Cerebrospinal Fluid From Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) With Rapid Evolution Affects Mitochondrial DNA Transcription and Network Organization in Human Glioblastoma Cells. [PDF]

J Med Virol
ABSTRACT Human T‐lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurodegenerative disease affecting motor and sensory functions. While alterations in cerebrospinal fluid (CSF) have been used to identify disease biomarkers, the effects of such modified CSF on CNS cells remain unexplored.
Gomes YCP, Bongers A, Jeannin P, Vicente ACP, Gessain A, Afonso PV, Espindola OM.   +6 more
europepmc   +2 more sources

Gut Microbiome Dysbiosis is Associated With Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection and Disease Progression to HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Cross-Sectional Study. [PDF]

Smart Med
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Fernandes LA, de Souza AO, Nukui Y, Marcusso RM, de Oliveira ACP, Casseb J, Clissa PB, Villas-Boas SG, Sanabani SS.   +8 more
europepmc   +2 more sources

Intravesical injection of onabotulinumtoxinA in neurogenic overactive bladder patients with human T‐cell leukemia virus type 1‐associated myelopathy: A single‐institution case series

IJU Case Reports, 2021
Introduction Neurogenic overactive bladder is a main feature of human T‐cell leukemia virus type 1‐associated myelopathy/tropical spastic paraparesis. We successfully performed intravesical onabotulinumtoxinA therapy for refractory neurogenic overactive ...
Tomohiro Matsuo, Tatsufumi Nakamura, Katsuya Sato, Yasuyoshi Miyata, Hideki Sakai   +4 more
doaj   +1 more source

Human T-Lymphotropic Virus Type 1-Associated Myelopathy With Autoimmune Cholangiopathy: An Unusual Immune Conundrum in a Young Patient. [PDF]

Case Rep Infect Dis
Human​ T‐lymphotropic virus type 1 (HTLV‐1), the first oncogenic retrovirus discovered in humans, is primarily associated with two disease entities: adult T cell leukemia‐lymphoma and HTLV‐1‐associated myelopathy‐tropical spastic paresis. HTLV‐1 has also been implicated in the pathogenesis of various autoimmune rheumatic diseases, and its association ...
Saad A, Jadoon Y, Sabir R.
europepmc   +2 more sources