Results 51 to 60 of about 6,507 (208)
From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley +1 more source
The HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), a myelopathy with predominant involvement of the pyramidal tract with minimal sensory loss and associated with HTLV-I infection, endemic in tropical areas, has been identified in ...
Sérgio Roberto Haussen +1 more
doaj +1 more source
Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr. +20 more
wiley +1 more source
PERFORMANCE OF THE GAIT IN INDIVIDUALS WITH HTLV-1: SYSTEMATIC REVIEW
HTLV-1 is frequently associated with myelopathy/tropical spastic paraparesis (HAM/TSP), which in turn brings several functional alterations to the individual, including changes in gait.
Mateus Evangelista do Amparo Santana +3 more
doaj +1 more source
Status of soluble ST2 levels in serum of HTLV-1 infected individuals [PDF]
ST2 is a member of IL-1 receptor family expressed on Th2 cells and regulates Th2 responces. The gene of ST2 encodes soluble ST2 (sST2) and the transmembrane ST2 (ST2L) isoforms through alternative mRNA splicing.
Avval, Farnaz Zahedi +5 more
core +1 more source
Human T-cell lymphotropic virus type I (HTLV-I) is the cause of endemic tropical spastic paraparesis (TSP) or HTLV-I-associated myelopathy (HAM). Because TSP/HAM is not a fatal disease, the neuropathology of this disease, albeit relatively well understood, is based on the examination of just a few incidental cases.
J, Buczyński +10 more
openaire +1 more source
ABSTRACT Grass pea (Lathyrus sativus L.) is a climate‐smart legume crop widely grown in Ethiopia, well‐known for its resilience to abiotic stresses, and serves as an insurance crop. Despite its ecological and agronomic benefits, the crop's market supply remains underexplored from both economic and sustainability perspectives.
Yosef Worku Yigezu +2 more
wiley +1 more source
Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report)
We investigated the efficacy of danazol treatment in eight patients with HTLV-l associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 ...
Ailton Melo +3 more
doaj +1 more source
O autor disserta sobre a definição de Paraparesia Espástica Tropical desde suas primeiras descrições até o envolvimento etiológico do HTLV-1 em parte dos casos.
Carlos Maurício de Castro-Costa
doaj +1 more source
Balance assessment in HTLV-1 associated myelopathy or tropical spastic paraparesis
INTRODUCTION: A good rating of the device in people with HTLV-1 in this population is essential for accuracy in prescribing data (walking). Thus, this study aimed to analyze the counterpart assessment methods that are best suited to patients with human T-
Naiane Araújo Patrício +6 more
doaj +1 more source

