Results 71 to 80 of about 4,843 (183)

Inhibitors of Tax1‐PDZ Interactions Block HTLV‐1 Viral Transmission by Changing EV Composition

Journal of Extracellular Vesicles, Volume 14, Issue 8, August 2025.
ABSTRACT Extracellular vesicles (EVs) are known to facilitate infection by enveloped RNA viruses including the Human T‐cell leukemia virus type‐1 (HTLV‐1). HTLV‐1‐encoded proteins, like the transactivator and oncoprotein Tax‐1, are loaded into EVs but their precise impact on EV cargos is not yet known.
Jedidja Puttemans, Yasmine Brammerloo, Karim Blibek, Jeremy Blavier, Thandokuhle Ntombela, Inge Van Molle, Julie Joseph, Julien Olivet, Deeya Saha, Manon Degey, Malik Hamaidia, Pooja Jain, Piel Geraldine, Pascale Zimmermann, Dae‐Kyum Kim, Dominique Baiwir, Makon‐Sébastien Njock, Franck Dequiedt, Kourosh Salehi‐Ashtiani, Steven Ballet, Alexander N. Volkov, Jean‐Claude Twizere, Sibusiso B. Maseko   +22 more
wiley   +1 more source

A Contribution to Nutrition in cases of Tropical Spastic Paraparesis due to HTLV-I. [PDF]

, 2007
The objective of this study is to describe intestinal constipation for HTLV-I virus and to analyze the role of dietary fiber and hydric consumption in the prevention and/or treatment of constipation in this group.
Capelli, Jane, Rodrigues Amorim Adegboye, Amanda; id_orcid, Pereira, Silvia Eliza, de Moraes, Viviane, Toste, Fernanda P, Porte, Alexandre, da Costa, Paula, de Almeida, Maria Fernanda, Santos Cardoso, Claudia, Toste, Fabiane, dos Santos Cople Rodrigues, Claudia   +10 more
core   +1 more source

HTLV‐1 infection altered expression of CCR2, CXCR2, eNOS genes, and oxidative stress in aorta and heart of male mice

Physiological Reports, Volume 13, Issue 11, June 2025.
Abstract Viral infections are associated with the disruption of oxidative stress and the progression of inflammatory mechanisms that play pivotal roles in cardiovascular diseases. In the present study, several inflammatory and oxidative stress markers were examined in HTLV‐1‐infected male BALB/c mice.
Saeed Niazmand, S. A. Rahim Rezaee, Jamshid Gholizadeh Navashenaq, Nema Mohamadian Roshan, Mohsen Ghoryani, Houshang Rafatpanah, Maryam Mahmoudabady, Yousef Baghcheghi, Maryam Paseban, Mahdiyeh Hedayati‐Moghadam   +9 more
wiley   +1 more source

On the etiology of tropical spastic paraparesis and human T-cell lymphotropic virus I-—Associated myelopathy

, 1999
The purpose of this review is to present some concepts on the etiology of tropical spastic paraparesis or human T-cell lymphotropic virus-I (HTLV-I)-associated myelopathy (TSP/HAM).
Zaninovic, Vladimir
core   +1 more source

Enhancing Crop Nutrition in Arid and Semiarid Regions of Africa Through Genome Editing Using CRISPR/Cas

Food and Energy Security, Volume 14, Issue 3, May/June 2025.
ABSTRACT Food insecurity is a pressing issue in Africa, aggravated by escalating drought, jeopardizing the region's ability to meet nutritional requirements for human health. In arid and semiarid regions, crop yield is severely affected by drought and salinity.
Erick Amombo, Rita H. Mumm, Abdelaziz Nilahyane, Abdelaziz Hirich, Mohamed Hijri, Valentine Otang Ntui   +5 more
wiley   +1 more source

Rewired chromatin structure and epigenetic gene dysregulation during HTLV‐1 infection to leukemogenesis

Cancer Science, Volume 116, Issue 2, Page 513-523, February 2025.
We analyzed and evaluated cells infected with human T‐cell leukemia virus type 1 at different stages of infection in terms of gene expression and chromatin structure using ATAC sequencing and RNA sequencing. Our results revealed that infected cells exhibited significant changes in gene expression patterns from the polyclonal stage and before adult T ...
Jun Mizuike, Kako Suzuki, Shu Tosaka, Yuta Kuze, Seiichiro Kobayashi, Makoto Nakashima, Koji Jimbo, Yasuhito Nannya, Yutaka Suzuki, Kaoru Uchimaru, Makoto Yamagishi   +10 more
wiley   +1 more source

Clinical characteristics and pathogenesis of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) [PDF]

Human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic progressive myelopathy characterized by spastic paraparesis and sphincter dysfunction observed in a minority of HTLV-1 infected ...
斎藤, 峰輝, Saito, Mineki
core  

HTLV-I Associated uveitis, myelopathy, rheumatoid arthritis and Sjögren's syndrome Uveite, mielopatia, artrite reumatóide e sindrome de Sjogren associadas ao HTLV-I

Arquivos de Neuro-Psiquiatria, 1995
A 62 year-old white female presented with a 10-year-history of slowly progressive spastic paraparesis, pain and dysesthesia in the lower limbs and sphincter disturbance.
Sônia Regina A. A. Pinheiro, Marco Aurélio Lana-Peixoto, Anna B. Carneiro Proietti, Fernando Oréfice, Maria V. Lima-Martins, Fernando A. Proietti   +5 more
doaj   +1 more source

Epilepsia secundária a neurocisticercose: número de calcificações x tipos de crises [PDF]

, 2001
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Newton, Fábio Antunes
core  

Strengthening awareness and response to HTLV‐1 infection in Africa: A neglected threat to blood safety and public health

HemaSphere, Volume 9, Issue 10, October 2025.
Jean‐Claude Twizere, Carolina Rosadas, Maureen Kidiga, Fatumata Djalo, Edward L. Murphy, Augustin Mouinga‐Ondeme, Marion Vermeulen, Louine Morrell, Saliou Diop, Sibusiso Maseko, Peregrine Sebulime, Andrews Akwasi Agbleke, Boineelo Fundisi, Espérance Umumararungu, Patricia Watber, Carol Hlela, Egídio Nhavene, Thato Chidarikire, Olivier Hermine, Antoine Gessain   +19 more
wiley   +1 more source