Results 61 to 70 of about 4,843 (183)

From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma

Cancer Science, Volume 117, Issue 2, Page 289-296, February 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley   +1 more source

Tropical spastic paraparesis in Kerala, South India

, 2003
Tropical Spastic Paraparesis (TSP) is an uncommon myeloneuropathy with an insular geographic distribution. In 1985, Human T-lymphotropic virus type I (HTLV-1) was reported to be a possible etiological factor.1 We did an epidemiological, clinical and ...
A. Oomman, M. Madhusoodanan
core   +2 more sources

PERFORMANCE OF THE GAIT IN INDIVIDUALS WITH HTLV-1: SYSTEMATIC REVIEW

Revista Pesquisa em Fisioterapia, 2017
HTLV-1 is frequently associated with myelopathy/tropical spastic paraparesis (HAM/TSP), which in turn brings several functional alterations to the individual, including changes in gait.
Mateus Evangelista do Amparo Santana, Livia Aguiar Pereira, Rafael Monteiro, Erika Pedreira Fonseca   +3 more
doaj   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source

The Relevance of HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis in Iran: A Review Study [PDF]

Reviews in Clinical Medicine, 2019
Human T-cell lymphotropic virus type I (HTLV-I) is a retrovirus, which is the causative agent of adult T-cell leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Masoud Keikha, mohsen Karbalaei Zadeh Babaki, Luiz Augusto Marcondes Fonseca, Jorge Casseb   +3 more
doaj   +1 more source

Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report)

Arquivos de Neuro-Psiquiatria, 1992
We investigated the efficacy of danazol treatment in eight patients with HTLV-l associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 ...
Ailton Melo, Luciana Moura, Ana Meireles, Gerçonita Costa   +3 more
doaj   +1 more source

Drivers of Grass Pea (Lathyrus sativus L.) Market Supply and Its Sustainability Payoffs: Evidence From Jama District, Ethiopia

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT Grass pea (Lathyrus sativus L.) is a climate‐smart legume crop widely grown in Ethiopia, well‐known for its resilience to abiotic stresses, and serves as an insurance crop. Despite its ecological and agronomic benefits, the crop's market supply remains underexplored from both economic and sustainability perspectives.
Yosef Worku Yigezu, Zenebu Shewakena Sidell, Tessema Astatkie   +2 more
wiley   +1 more source

Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis. [PDF]

, 2020
INTRODUCTION: In patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) gait disturbance is a predominant feature that leads to falls and fractures, which can further aggravate disability.
Tipismana, Martín, Schwalb, Alvaro, Alvarez, Carolina, Cachay, Rodrigo, González-Lagos, Elsa, Julca-Copello, Pablo, Gotuzzo, Eduardo, Mejía, Fernando   +7 more
core   +1 more source

Epidural labour anaesthesia in a patient with tropical spastic paraparesis

, 2023
Human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM), also called tropical spastic paraparesis (TSP), is a medical condition that is associated with symptoms including muscle spasms, sensory disturbances causing paraparesis, and ...
Suzanne Lilker (16732163), Savannah Grodecki (16732160), Dimitrios Dimitrakoudis (16732165), Jose Carvalho (1585417), Arvind Khambla (16732167), Joseph Bremang (16732164)   +5 more
core   +1 more source

Tropical spastic paraparesis.

Folia neuropathologica, 2002
Human T-cell lymphotropic virus type I (HTLV-I) is the cause of endemic tropical spastic paraparesis (TSP) or HTLV-I-associated myelopathy (HAM). Because TSP/HAM is not a fatal disease, the neuropathology of this disease, albeit relatively well understood, is based on the examination of just a few incidental cases.
J, Buczyński, R, Yanagihara, C, Mora, L, Cartier, A, Verdugo, F, Araya, L, Castillo, C J, Gibbs, C D, Gajdusek, P, Rogers-Johnson, P P, Liberski   +10 more
openaire   +1 more source