SPG10 is a rare cause of spastic paraplegia in European families [PDF]
, 2008 Background: SPG10 is an autosomal dominant form of hereditary spastic paraplegia (HSP), which is caused by mutations in the neural kinesin heavy chain KIF5A gene, the neuronal motor of fast anterograde axonal transport.
Auer-Grumbach, M. +10 more
core +13 more sources
Hereditary spastic paraplegia type 5: natural history, biomarkers and a randomized controlled trial
Brain, 2017 Ludger Schöls +2 more
exaly +2 more sources
Magnetic Resonance Imaging of Trunk Musculature and Intervertebral Discs in Patients with Spinal Cord Injury with Thoracolumbar Vertebral Fractures: A Prospective Study [PDF]
Asian Spine Journal, 2020 Study Design This study is a prospective clinical study. Purpose This study aims to evaluate the characteristics of trunk musculature and intervertebral discs by using magnetic resonance imaging in patients with spinal cord injuries (SCIs) with thoracic ...
Roop Singh +4 more
doaj +1 more source
Spine Surgery and Related Research, 2023 Introduction: Conventional magnetic resonance imaging findings frequently do not correlate with the symptoms of lumbar disc herniation (LDH). Diffusion-weighted imaging can reveal important details about the microstructure of tissues. This study assessed
Roop Singh +5 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2021 Background To explore the therapeutic effect of early surgical intervention for active thoracic spinal tuberculosis (TB) patients with paraparesis and paraplegia.
Weiwei Li +6 more
semanticscholar +1 more source
Outcome of Pedicle Screw Fixation and Monosegmental Fusion in Patients with Fresh Thoracolumbar Fractures [PDF]
Asian Spine Journal, 2014 Study DesignProspective clinical study.PurposeThe present prospective study aims to evaluate the clinical, radiological, and functional and quality of life outcomes in patients with fresh thoracolumbar fractures managed by posterior instrumentation of ...
Roop Singh +4 more
doaj +1 more source
Limited Laminectomy and Restorative Spinoplasty in Spinal Canal Stenosis [PDF]
Asian Spine Journal, 2014 Study DesignProspective cohort study.PurposeEvaluation of the clinico-radiological outcome and complications of limited laminectomy and restorative spinoplasty in spinal canal stenosis.Overview of LiteratureIt is critical to achieve adequate spinal ...
Sukhbir Singh Sangwan +5 more
doaj +1 more source
Evaluation of the Behavior of Spinal Deformities in Tuberculosis of the Spine in Adults [PDF]
Asian Spine Journal, 2015 Study DesignA prospective clinical study.PurposeThe objective of the present study was to evaluate the behavior of spinal deformities in tuberculosis (TB) of the spine during the initial 2 years and to suggest remedial measures.Overview of ...
Roop Singh, Narender Kumar Magu
doaj +1 more source
Effects of Resistance Circuit Training on Health-Related Physical Fitness in People With Paraplegia: A Pilot Randomized Controlled Trial [PDF]
Annals of Rehabilitation Medicine, 2022 Objective To evaluate the efficacy and safety of 8 weeks of resistance circuit training in people with paraplegia due to spinal cord injury. Methods Participants were randomized into experimental and control groups. Although the intensity and sequence of
Minkyoung Son +8 more
doaj +1 more source
Journal of Orthopaedics, Trauma and Rehabilitation, 2023 Objectives: Studies in the past were not able to find any definitive correlation between disc parameters and LBP. The objectives of the current study were to evaluate the association of the lumbar disc parameters with LBP and to find the quantitative ...
Roop Singh +5 more
doaj +1 more source