Results 41 to 50 of about 77,736 (278)

Defective axonal transport in motor neuron disease [PDF]

open access: yes, 2007
Several recent studies have highlighted the role of axonal transport in the pathogenesis of motor neuron diseases. Mutations in genes that control microtubule regulation and dynamics have been shown to cause motor neuron degeneration in mice and in a ...
Baas   +77 more
core   +1 more source

Pain in paraplegia [PDF]

open access: yesSpinal Cord, 1973
A clinical impression of a significant difference in the incidence of pain among spinal paralytics at two Spinal Centres, one in Australia, the other in the United States, has been substantiated by a survey of the patients of the two Centres. A detailed analysis of the possible factors explaining this difference in the incidence of pain was carried out
openaire   +3 more sources

Rescue axonal defects by targeting mitochondrial dynamics in hereditary spastic paraplegias

open access: yesNeural Regeneration Research, 2019
Impaired axonal development and degeneration underlie debilitating neurodegenerative diseases including hereditary spastic paraplegia, a large group of inherited diseases.
Yongchao Mou, Xue-Jun Li
doaj   +1 more source

Personal, family and societal educational needs assessment of individuals with spinal cord injury in Iran [PDF]

open access: yes, 2018
Objectives: To explore individuals’ perception of the personal, family and societal educational needs following a spinal cord injury. Methods: Sixty-one patients who sustained a traumatic SCI between March 2015 and June 2016 referred to Brain and Spinal ...
Abd-Mousavi, Afsaneh   +8 more
core   +2 more sources

Biomechanics of Pediatric Manual Wheelchair Mobility [PDF]

open access: yes, 2015
Currently, there is limited research of the biomechanics of pediatric manual wheelchair mobility. Specifically, the biomechanics of functional tasks and their relationship to joint pain and health is not well understood.
Aurit, Christine M.   +5 more
core   +3 more sources

Further supporting evidence for REEP1 phenotypic and allelic heterogeneity. [PDF]

open access: yes, 2019
Heterozygous mutations in REEP1 (MIM #609139) encoding the receptor expression-enhancing protein 1 (REEP1) are a well-recognized and relatively frequent cause of autosomal dominant hereditary spastic paraplegia (HSP), SPG31.1 REEP1 localizes in the ...
Behnam, M   +5 more
core   +3 more sources

Paraplegia in women [PDF]

open access: yesSpinal Cord, 1983
In the period 1965-80, 125 women were treated because of paralysis or paresis of the lower extremities resulting from spinal trauma. In this report the causes of trauma, as well as the clinical and functional treatment of this group are discussed. The most frequent causes of trauma were falls from heights, from a tree, a ladder, a horse-cart as well as
Shaban H Ahmad, Kiwerski J
openaire   +3 more sources

Fra‐1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury

open access: yesBrain Pathology, Volume 33, Issue 1, January 2023., 2023
Schematic illustration depicting the mechanism by which Fra‐1‐mediated S100A8/TLR4/NF‐κB and ERK signaling in the regulation of apoptosis and neuroinflammation during spinal I/R. Abstract Spinal cord ischemia/reperfusion injury (SCII) is a severe complication driven by apoptosis and neuroinflammation. An increase in the expression of c‐Fos, a member of
Ying Chen   +6 more
wiley   +1 more source

Efeito do treinamento físico de membros superiores aeróbio de curta duração no deficiente físico com hipertensão leve [PDF]

open access: yesArquivos Brasileiros de Cardiologia, 1997
OBJETIVO: Verificar as alterações provocadas pelo treinamento físico (TF), com membros superiores (MMSS), em condição aeróbia de curta duração, sobre variáveis dos sistemas cardiovascular e metabólico. MÉTODOS: Foram estudados 11 deficientes físicos (DF)
Sandra Haddad   +3 more
doaj   +1 more source

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