BackgroundSome human poxvirus infections can be acquired through zoonotic transmission. We report a previously unknown poxvirus infection in 2 patients, 1 of whom was immunocompromised; both patients had known equine contact.MethodsThe patients were ...
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Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor [PDF]
Viruses have long been studied not only for their pathology and associated disease but also as model systems for understanding cellular and immunological processes. Rodent herpesvirus Peru (RHVP) is a recently characterized rhadinovirus related to murine
Alcami +58 more
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ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus Therapeutic
Replicating viruses for the treatment of cancer have a number of advantages over traditional therapeutic modalities. They are highly targeted, self-amplifying, and have the added potential to act as both gene-therapy delivery vehicles and oncolytic agents.
Rintoul, Julia L +14 more
openaire +2 more sources
Comparative and retrospective molecular analysis of Parapoxvirus (PPV) isolates
Species members of the genus Parapoxvirus (PPV) within the family Poxviridae cause contagious pustular dermatitis in small ruminants (Orf virus, ORFV) and mostly mild localized inflammation in cattle (bovine papular stomatitis virus, BPSV and pseudocowpox virus, PCPV).
Schirin, Friederichs +6 more
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A Case of Orf Disease Complicated with Erythema Multiforme and Bullous Pemphigoid-Like Eruptions
Parapoxvirus infection in sheep and goats is usually referred to as contagious pustular dermatitis/ecthyma, or orf, and the corresponding human infection is referred to as orf.
Shahriar Alian +2 more
doaj +1 more source
Emerging infectious disease implications of invasive mammalian species : the greater white-toothed shrew (Crocidura russula) is associated with a novel serovar of pathogenic Leptospira in Ireland [PDF]
The greater white-toothed shrew (Crocidura russula) is an invasive mammalian species that was first recorded in Ireland in 2007. It currently occupies an area of approximately 7,600 km2 on the island. C. russula is normally distributed in Northern Africa
A Mayer-Scholl +73 more
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Polarised VEGFA Signalling at Vascular Blood–Neural Barriers [PDF]
At blood–neural barriers, endothelial VEGFA signalling is highly polarised, with entirely different responses being triggered by luminal or abluminal stimulation. These recent findings were made in a field which is still in its mechanistic infancy. For a
Dragoni, S, Turowski, P
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Feast of Sacrifice and Orf, Milan, Italy, 2015–2018
Orf (ecthyma contagiosum) is an infection of the skin caused by a DNA virus belonging to the genus Parapoxvirus. We recently observed 7 cases of orf in Muslim men living in the metropolitan area of Milan, Italy, who acquired the infection after the Feast
Stefano Veraldi +4 more
doaj +1 more source
Characterization of immunostimulatory components of orf virus (parapoxvirus ovis)
Inactivated orf virus (ORFV, parapoxvirus ovis) induces antiviral activity in animal models of acute and chronic viral infections and exerts strong effects on human immune cells. ORFV activates antigen presenting cells (APC) via CD14 and, probably, Toll-like receptor signalling, and triggers the release of IFN-γ that has been identified as the key ...
Astrid, Friebe +9 more
openaire +2 more sources
Rare human skin infection with Corynebacterium ulcerans: transmission by a domestic cat [PDF]
Corynebacterium ulcerans is mainly known for its ability to cause animal infections. Some strains of C. ulcerans produce diphtheria toxin, which can cause life-threatening cardiopathies and neuropathies in humans. Human cutaneous C. ulcerans infection is
Bloemberg, G. +6 more
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