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Molecular Genetic Analysis of Orf Virus: A Poxvirus That Has Adapted to Skin
Orf virus is the type species of the Parapoxvirus genus of the family Poxviridae. It induces acute pustular skin lesions in sheep and goats and is transmissible to humans. The genome is G+C rich, 138 kbp and encodes 132 genes.
Stephen B. Fleming +2 more
doaj +1 more source
Hematological and biochemical evaluation of goats naturally infected with contagious ecthyma [PDF]
Contagious ecthyma (CE) is a zoonotic skin disease of small ruminants, caused by an epitheliotropic parapoxvirus and has a worldwide distribution with significant economic importance.
Seyed Amin Kazemi Asl +3 more
doaj +1 more source
Seal parapoxvirus (SPPV) infection has been reported among pinnipeds in aquaria in Japan; however, its seroprevalence is unknown. Therefore, an enzyme-linked immunosorbent assay (ELISA) was developed for serological diagnosis of SPPV infection.
Badr Yassien +9 more
doaj +1 more source
Structural conservation and functional diversity of the Poxvirus Immune Evasion (PIE) domain superfamily [PDF]
Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any ...
Alcami +40 more
core +3 more sources
European red squirrel population dynamics driven by squirrelpox at a gray squirrel invasion interface [PDF]
European red squirrel population dynamics driven by squirrelpox at a gray squirrel invasion ...
core +3 more sources
Parapoxvirus real-time PCR v2 [PDF]
A real-time PCR for Parapoxvirus targeting the DNA polymerase. It is used to screen human samples where Parapoxvirus is suspected. This protocol is based on the published RVSS assay by Das et al 2017. Oligonucleotides have been modified and a different PCR kit is used.
Judy A Northill, Ian M Mackay
openaire +1 more source
Background: Previous serological screenings have indicated that Eurasian semi-domesticated tundra reindeer (Rangifer tarandus tarandus) in Finnmark, Northern Norway, are exposed to alphaherpesvirus, gammaherpesvirus and pestivirus. Alphaherpesvirus (i.e.,
Morten Tryland +10 more
doaj +1 more source
Parapoxvirus of red deer in New Zealand (PVNZ) is a species of the Parapoxvirus genus that causes pustular dermatitis. We identified a cluster of genes in PVNZ that encode three unique chemokine-binding proteins (CBPs) namely ORF112.0, ORF112.3 and ...
Saeed Sharif +7 more
doaj +1 more source
Detection of myxoma viruses encoding a defective M135R gene from clinical cases of myxomatosis; possible implications for the role of the M135R protein as a virulence factor [PDF]
Background: Myxoma virus is a member of the Poxviridae and causes disease in European rabbits. Laboratory confirmation of the clinical disease, which occurs in the autumn of most years in Denmark, has been achieved previously using antigen ELISA and ...
Graham J Belsham +25 more
core +2 more sources
Orf parapoxvirus infection from a cat scratch
A 53-year-old woman presented with an enlarging, tender, ulcerated nodule on her dorsal hand after being scratched by a stray kitten. Histology was consistent with orf parapoxvirus infection. The lesion resolved without scarring after several weeks of treatment with imiquimod 5 percent cream. Orf is a zoonosis transmitted to humans from sheep and goats
Frandsen, Jonathan +2 more
openaire +4 more sources

