Results 71 to 80 of about 3,862 (200)

Protective immune response against Rhodococcus equi: An innate immunity‐focused review

Equine Veterinary Journal, Volume 57, Issue 3, Page 563-586, May 2025.
Abstract Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune
Bibiana Petri da Silveira, Noah D. Cohen, Sara D. Lawhon, Robert O. Watson, Angela I. Bordin   +4 more
wiley   +1 more source

Novel Multi-Antigen Orf-Virus-Derived Vaccine Elicits Protective Anti-SARS-CoV-2 Response in Monovalent and Bivalent Formats

Vaccines
Prime-2-CoV_Beta is a novel Orf virus (ORFV)-based COVID-19 vaccine candidate expressing both the nucleocapsid and spike proteins of SARS-CoV-2 with the receptor-binding domain (RBD) of the Beta strain. This candidate was shown to be safe and immunogenic
Dominique Julien Burri, Louis Renz, Melanie Mueller, Felix Pagallies, Ute Klinkhardt, Ralf Amann, Madiha Derouazi   +6 more
doaj   +1 more source

Detection of pseudocowpox virus in water buffalo (Bubalus bubalis) with vesicular disease in the state of São Paulo, Brazil, in 2016

Veterinary Quarterly, 2017
Background: Parapoxviruses are zoonotic viruses that infect cattle, goats and sheep; there have also been reports of infections in camels, domestic cats and seals. Objective: The objective of this report was to describe a case of vesicular disease caused
Mateus Laguardia-Nascimento, Ana Paula Ferreira de Oliveira, Fernanda Rodas Pires Fernandes, Anselmo Vasconcelos Rivetti, Marcelo Fernandes Camargos, Antônio Augusto Fonseca Júnior   +5 more
doaj   +1 more source

Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity

Nature Communications, 2023
Oncolytic viruses are able to target tumours and thought to induce apoptosis while remodelling the tumour immune microenvironment. Here authors show in an oncolytic parapoxvirus ovis model that pyroptosis, a highly immunogenic Gasdermin-E-dependent cell ...
Jing Lin, Shihui Sun, Kui Zhao, Fei Gao, Renling Wang, Qi Li, Yanlong Zhou, Jing Zhang, Yue Li, Xinyue Wang, Le Du, Shuai Wang, Zi Li, Huijun Lu, Yungang Lan, Deguang Song, Wei Guo, Yujia Chen, Feng Gao, Yicheng Zhao, Rongrong Fan, Jiyu Guan, Wenqi He   +22 more
doaj   +1 more source

Characterisation and Sensitivity of a Canine Mast Cell Tumour Line to Oncolytic Viruses

Veterinary and Comparative Oncology, Volume 23, Issue 1, Page 42-51, March 2025.
ABSTRACT Canine mast cell tumours (MCTs) are one of the most common skin cancers of dogs. Surgical removal is the primary treatment, but recurrence and metastasis can occur even with low‐grade tumours. As a result, new treatment strategies are being sought.
Yeganeh Mehrani, Julia E. Kakish, Christina Napoleoni, Jennifer Jane Thompson, Jason P. Knapp, Jessica A. Minott, Jacob G. E. Yates, Deirdre Stuart, Brenda L. Coomber, Robert A. Foster, Byram W. Bridle, Khalil Karimi   +11 more
wiley   +1 more source

РІДКІСНА ПРОФЕСІЙНА ІНФЕКЦІЯ: ДВА ВИПАДКИ ПАРАВАКЦИНИ - ВІРУСНОЇ ХВОРОБИ ДОЯРОК НА БУКОВИНІ [PDF]

, 2018
У представленій статті наведено два клінічні випадки рідкісної зоонозної професійної вірусної інфекційної хвороби, викликаної ДНК-вмісним парапоксвірусом, який передається безпосередньо під час контакту, найчастіше при доїнні корів, що й спричинило ...
Богачик, Н.А., Венгловська, Я.В., Каспрук, Н.А., Олійник, О.М., Рандюк, Ю.О., Сидорчук, А.С., Сокол, А.М., Тимощук, В.Л.   +7 more
core  

The ovarian cancer oncobiome. [PDF]

, 2017
Humans and other mammals are colonized by microbial agents across the kingdom which can represent a unique microbiome pattern. Dysbiosis of the microbiome has been associated with pathology including cancer.
Alwine, J.C., Banerjee, S., Coukos, G., Feldman, M.D., Robertson, E.S., Shih, N., Tian, T., Wei, Z.   +7 more
core   +2 more sources

Sorting Out Pandora’s Box: Discerning the Dynamic Roles of Liver Microenvironment in Oncolytic Virus Therapy for Hepatocellular Carcinoma [PDF]

, 2014
Oncolytic viral therapies have recently found their way into clinical application for hepatocellular carcinoma (HCC), a disease with limited treatment options and poor prognosis. Adding to the many intrinsic challenges of in vivo oncolytic viral therapy,
Jennifer Altomonte, Oliver Ebert
core   +3 more sources

Next‐Generation Vaccines for Co‐Circulating PEDV and TGEV: Integrating Nucleic Acid Platforms, Mucosal Delivery, and AI–Driven Antigen Design

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) are causative agents of acute enteric diseases in pigs and have a high contagion potential. These coronaviruses (CoVs) impose substantial economic losses on global pork production, particularly affecting lactating piglets where coinfections occur. Although traditional
Xiaojun Hu, Zhenshan Wang, Shen Wang, Hongyu Sun, Na Feng, Entao Li, Xianzhu Xia, Guixue Hu, Feihu Yan, Bin Li   +9 more
wiley   +1 more source

Molecular epidemiology of camel contagious ecthyma in Arero district, Ethiopia

Bulletin of the National Research Centre, 2022
Background While dromedary camels (Camelus dromedarius) were traditionally believed to be resistant to most livestock diseases, research has demonstrated that they are susceptible to a large number of infectious agents.
Bareda Diba, Benti Deresa Gelalcha, Birhanu Ayele, Bedane Adane, Paul J. Plummer   +4 more
doaj   +1 more source