Are African primary physicians suspicious enough? Challenges of multiple myeloma diagnosis in Africa
Background Multiple myeloma is a hematological malignancy of plasma cells belonging to a spectrum of monoclonal protein-secreting disorders known as paraproteinemias.
Erick Thokerunga +2 more
doaj +1 more source
Bilateral Crystalline Corneal Deposits as First Clinical Manifestation of Monoclonal Gammopathy: A Case Report [PDF]
Aims: To report the clinical and diagnostic findings of a patient with bilateral corneal deposits caused by an underlying monoclonal gammopathy. Methods: Slit-lamp biomicroscopy, confocal microscopy and additional serological tests were performed on a 35-
Eddy, Mau-Thek +6 more
core +3 more sources
Plasmaferese em neurologia análise crítica da indicação e protocolos
Por ser a plasmaferese método terapêutico moderno e seguro, ela é cada vez mais indicada em doenças ligadas etiopatogenicamente à imunologia. Propomo-nos analisar suas indicações no âmbito da neurologia. Discutimos e analisamos sua indicação em miastenia
José Carlos Brant Seggia, Paulo Abreu
doaj +1 more source
Genetics and molecular epidemiology of multiple myeloma : the rationale for the IMMEnSE consortium (review) [PDF]
There is strong evidence suggesting the presence of a genetic component in the aetiology of multiple myeloma (MM). However no genetic risk factors have been unequivocally established so far.
Buda, Gabriele +19 more
core +1 more source
Contribution of the laboratory to a diagnosis process by sequential reflective testing: Paraprotein interference on a direct bilirubin assay [PDF]
Errors in laboratory medicine occur in the preanalytical, analytical, and postanalytical phases. The errors are mostly detected in the preanalytical period.
Gülbahar, Özlem +2 more
core +2 more sources
Recurrence of membranoproliferative glomerulonephritis (MPGN) is seen in 1965% cases of postrenal transplant resulting in graft loss in up to 35-50% of cases.
Umesh Lingaraj +5 more
doaj +1 more source
Monoclonal gammopathy of undetermined significance : natural course and comorbidities [PDF]
Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder characterized by an overproduction of monoclonal immunoglobulins.
Lindqvist, Ebba K
core +1 more source
Diffuse plane normolipemic xanthomatosis (DPNX) is a rare, non-inherited disease that is often associated with systemic diseases, mainly malignant hematological (especially multiple myeloma) or lymph proliferative disorders.
Aristóteles Rosmaninho +4 more
doaj +1 more source
Polymorphism of alpha-1-antitrypsin in hematological malignancies [PDF]
Alpha-1-antitrypsin (AAT) or serine protease inhibitor A1 (SERPINA1) is an important serine protease inhibitor in humans. The main physiological role of AAT is to inhibit neutrophil elastase (NE) released from triggered neutrophils, with an additional ...
Aleksandra Topic +27 more
core +4 more sources
ESCLEREDEMA DE BUSCHKE – A propósito de um caso clínico
RESUMO: O Escleredema de Buschke (EB) é uma doença rara do tecido conjuntivo, de etiologia desconhecida, caracterizada por espessamento e endurecimento da pele, geralmente localizado nas regiões proximais e posteriores do tronco e pescoço.
Jorge Henriques +3 more
doaj +1 more source

