Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration [PDF]
, 2018 Mutations in Cu/Zn superoxide dismutase 1 (SOD1) lead to Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease that disproportionately affects glutamatergic and cholinergic motor neurons.
Baskoylu, Saba N +10 more
core +3 more sources
Superoxide Dismutase of Micrococcus sp. S2 and Its Involve in Paraquat Detoxification
Indonesian Journal of Biotechnology, 2007 As an active ingredient of herbicide, paraquat will induce formation of superoxide radicals. The previous research succeeded in isolating paraquat degrading bacteria from peat soil, Micrococcus sp. S2, that tolerant to high concentration of paraquat.
Sebastian Margino +2 more
doaj +1 more source
Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin [PDF]
, 2010 Loss of the E3 ubiquitin ligase Parkin causes early onset Parkinson's disease, a neurodegenerative disorder of unknown etiology. Parkin has been linked to multiple cellular processes including protein degradation, mitochondrial homeostasis, and autophagy;
A. J. Whitworth +28 more
core +2 more sources
Food Safety, 2022 Food Safety Commission of Japan (FSCJ) conducted a risk assessment of a bipyridinium herbicide, paraquat (CAS No. 1910-42-5), based on results from various studies. Major adverse effects of paraquat in experimental animals were observed in body weight (suppressed weight gain), lungs (increased weight, alveolar epithelium hyperplasia, and pneumonia ...
openaire +2 more sources
Comment on "Medical Management and Outcome of Paraquat Poisoning in Ahvaz, Iran: A Hospital-Based Study" [PDF]
Asia Pacific Journal of Medical Toxicology, 2016 Dear editor, We read the recent article of Rahmani et al entitled "Medical Management and Outcome of Paraquat Poisoning in Ahvaz, Iran: A Hospital-Based Study" in your journal (1).
Arman Otroshi +2 more
doaj +1 more source
Environmental risk factors and their footprints in vivo – a proposal for the classification of oxidative stress biomarkers [PDF]
, 2020 Environmental agents, including socioeconomic condition, and host factors can act as causal agents and risk factors in disease. We use biomarkers and sociomarkers to study causal factors, such as overproduction of reactive oxygen species (ROS) which ...
Ghezzi, Pietro
core +1 more source
Controle químico de Lolium multiflorum: efeito do biótipo e da época de aplicação
Revista de Ciências Agroveterinárias, 2017 Testou-se diferentes herbicidas para controle de dois biótipos de Lolium multiflorum, importante planta daninha de cultivos anuais e perenes, aplicados nos estádios de 3-4 folhas e de pré-florescimento.
Liese de Vargas Pereira +2 more
doaj +1 more source
Superoxide Dismutase (SOD)-mimetic M40403 is protective in cell and fly models of paraquat toxicity: Implications for Parkinson disease [PDF]
, 2016 Parkinson disease is a debilitating and incurable neurodegenerative disorder affecting 3c1-2% of people over 65 years of age. Oxidative damage is considered to play a central role in the progression of Parkinson disease and strong evidence links chronic
Beltramini, Mariano +8 more
core +1 more source
p120 catenin is required for the stress response in Drosophila [PDF]
, 2013 p120ctn is a ubiquitously expressed core component of cadherin junctions and essential for vertebrate development. Surprisingly, Drosophila p120ctn (dp120ctn) is dispensable for adherens junctions and development, which has discouraged Drosophila ...
Bauer, Christin +2 more
core +9 more sources
Elimination of young erythrocytes from blood circulation and altered erythropoietic patterns during paraquat induced anemic phase in mice. [PDF]
PLoS ONE, 2014 Paraquat a widely used herbicide causes a variety of toxic effects on humans and animals. The present study is focused on the interaction of paraquat with the mouse erythroid system. Administration of paraquat (10 mg/kg body weight i.p. on alternate days
Nitin Bhardwaj, Rajiv K Saxena
doaj +1 more source