Results 41 to 50 of about 2,882 (170)

Remaking State Power Through a Paraquat Ban in Malaysia

Journal of Agrarian Change, EarlyView.
ABSTRACT This paper examines the role of the state in its ability to enact environmental regulations. Specifically, this study investigates how Malaysian state actors changed, shifted and betrayed various, oftentimes competing interests to ban paraquat, an acutely toxic herbicide.
Caitlyn Sears
wiley   +1 more source

Pesticide Supply Chains From China to Australia: Examining Paraquat Amid the Global Pesticide Complex

Journal of Agrarian Change, EarlyView.
ABSTRACT Following recent calls to deepen understanding of the Global Pesticide Complex, this article delves into the China‐to‐Australia supply chain of a single herbicide—paraquat. First released in the United Kingdom in the 1960s, acutely toxic paraquat is now primarily produced in China.
Sarah Rogers, Yue Zhao, Sonia Graham, Brooke Wilmsen, Ju‐Han Zoe Wang   +4 more
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Evaluating the Suitability of HepaRG Cells for Regulatory Micronucleus Testing: Comparing Results for a Diverse Set of 28 Chemicals to Regulatory Accepted TK6 Cells

Environmental and Molecular Mutagenesis, Volume 67, Issue 5-7, June‐August 2026.
ABSTRACT There is growing interest in in vitro‐based new approach methodologies (NAMs) for assessing genotoxicity. These approaches are desirable for industries like cosmetics which are prohibited from animal testing due to regulatory restrictions, as well as “3R” considerations to avoid in vivo testing.
Ashley Allemang, Stefan Pfuhler
wiley   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source

Lethal mediastinal emphysema caused by inhalation of paraquat: a case report

BMC Pulmonary Medicine
This paper reports on a 22-year-old male presenting with persistent chest pain accompanied by mediastinal emphysema. We firstly considered mediastinal emphysema induced by community acquired pneumonia.
Qing Tang, Jiaqi Xu, Hao Wang, Lijun Wang   +3 more
doaj   +1 more source

When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich, Brent R. Stockwell, Marcelo Farina   +2 more
wiley   +1 more source

Treatment of Paraquat Poisoning with Cyclophosphamide / Dexamethasone Combination : The First Two Years Experience at Siriraj Hospital

Siriraj Medical Journal, 2004
While the mortality rate from paraquat is high, a proven treatment for paraquat poisoning is still lacked. In this article, we describe the outcome of the first two years of implementing a treatment protocol containing cyclophosphamide and dexamethasone ...
Summon Chomchai, Chulathida Chomchai, Teera Kolladarungkrai   +2 more
doaj  

Paraquat Poisoning: A Growing Homicidal Threat: Insights and Strategies

Journal of Medical Evidence
Paraquat is a widely used non-selective herbicide in Indian agriculture. It has gained popularity for its misuse in suicidal poisoning, primarily because it lacks an antidote, and ingestion often leads to death.
Kattamreddy Ananth Rupesh, Victor Ghosh
doaj   +1 more source

Re‐conceptualizing Parkinson's disease as a lifelong neurobiological trajectory: A framework for prevention

Neuroprotection, Volume 4, Issue 1, Page 14-29, March 2026.
Three‐panel graphical abstract showing the Lifelong Neurobiological Trajectory framework for Parkinson's disease: (1) Vulnerability pathway (top, red) showing how early adversity → epigenetic dysregulation, neuroinflammation, and mitochondrial dysfunction → ↑ PD risk; (2) Lifespan timeline (middle, purple) spanning prenatal/infancy → childhood ...
Ayodeji Johnson Ajibare, Abraham Olufemi Asuku, Olabode Oluwadare Akintoye   +2 more
wiley   +1 more source