Results 21 to 30 of about 645,334 (303)

The multifunctional autophagy pathway in the human malaria parasite, Plasmodium falciparum. [PDF]

, 2013
Autophagy is a catabolic pathway typically induced by nutrient starvation to recycle amino acids, but can also function in removing damaged organelles. In addition, this pathway plays a key role in eukaryotic development. To date, not much is known about
Bunnik, Evelien M, Cervantes, Serena, Conner, Christopher M, Escalante, Aster, Florens, Laurence, Le Roch, Karine G, Ponts, Nadia, Prudhomme, Jacques, Saraf, Anita, Sardiu, Mihaela E   +9 more
core   +4 more sources

Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions [PDF]

, 2016
Babesia microti, a tick-transmitted, intraerythrocytic protozoan parasite circulating mainly among small mammals, is the primary cause of human babesiosis.
Ben Mamoun, Choukri, Brancato, Jana, Chibucos, Marcus, Colinge, Jacques, Cornillot, Emmanuel, Crabtree, Jonathan, Dwivedi, Ankit, Fraser, Claire M., Frutos, Roger, Gotia, Hanzel T., Hung, Chris, Ifeonu, Olukemi O., Krause, Peter J., Kumar, Vidya, Kumari, Priti, Lawres, Lauren, McCracken, Carrie, Molina, Douglas M., Orvis, Joshua, Ott, Sandy, Pablo, Jozelyn V., Pazzi, Joseph E., Reynes, Christelle, Sadzewicz, Lisa, Sengamalay, Naomi, Shetty, Amol C., Silva, Joana C., Su, Qi, Tallon, Luke, Tretina, Kyle, Usmani-Brown, Sahar, Virji, Azan Z.   +31 more
core   +3 more sources

CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum

mBio, 2020
The human malaria parasite Plasmodium falciparum uses mutually exclusive expression of the PfEMP1-encoding var gene family to evade the host immune system. Despite progress in the molecular understanding of the default silencing mechanism, the activation
Anna Barcons-Simon, Carlos Cordon-Obras, Julien Guizetti, Jessica M. Bryant, Artur Scherf   +4 more
doaj   +1 more source

Biochemical characterization of Plasmodium falciparum parasite specific helicase 1 (PfPSH1)

FEBS Open Bio, 2019
Malaria, a disease caused by infection with parasites of the genus Plasmodium, causes millions of deaths worldwide annually. Of the five Plasmodium species that can infect humans, Plasmodium falciparum causes the most serious parasitic infection.
Manish Chauhan, Suman Sourabh, Rahena Yasmin, Isha Pahuja, Renu Tuteja   +4 more
doaj   +1 more source

Pathophysiology of Cerebral Malaria: Implications of MSCs as A Regenerative Medicinal Tool

Bioengineering, 2022
The severe form of malaria, i.e., cerebral malaria caused by Plasmodium falciparum, is a complex neurological syndrome. Surviving persons have a risk of behavioral difficulties, cognitive disorders, and epilepsy.
Amrendra Chaudhary, Poonam Kataria, Neha Surela, Jyoti Das   +3 more
doaj   +1 more source

Parasites lead to evolution of robustness against gene loss in host signaling networks [PDF]

, 2008
Many biological networks can maintain their function against single gene loss. However, the evolutionary mechanisms responsible for such robustness remain unclear.
Marcel Salathé, Orkun S Soyer, Agrawal A, Anderson RM, Bell G, de Wit PJ, Jaenike J, Wagner A   +7 more
core   +2 more sources

Parasitic plants [PDF]

Current Biology, 2018
In this quick guide, Twyford introduces the reader to parasitic plants, explaining how they steal nutrients from host plants and how this lifestyle has evolved multiple times in plants.
openaire   +3 more sources

Assessing the risk of an emerging zoonosis of worldwide concern : anisakiasis [PDF]

, 2017
The authors sincerely thank the Biobanking platform at the PARASITE project (EU FP7 PARASITE project (GA no. 312068)) for providing host-parasite data.
Bao Dominguez, Miguel, Bušelić, Ivana, Cipriani, Paolo, González-Muñoz, Miguel, Mattiucci, Simonetta, Mladineo, Ivona, Pascual, Santiago, Pierce, Graham J, Strachan, Norval J. C.   +8 more
core   +2 more sources

Evolutionary analysis of the most polymorphic gene family in falciparum malaria [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research, 2019
The var gene family of the human malaria parasite Plasmodium falciparum encode proteins that are crucial determinants of both pathogenesis and immune evasion and are highly polymorphic.
Thomas D. Otto, Sammy A. Assefa, Ulrike Böhme, Mandy J. Sanders, Dominic Kwiatkowski, Pf3k consortium, Matt Berriman, Chris Newbold   +7 more
doaj   +1 more source

CD4+ICOS+Foxp3+: a sub-population of regulatory T cells contribute to malaria pathogenesis

Malaria Journal, 2022
Background Regulatory T cells are known to play a key role to counter balance the protective immune response and immune mediated pathology. However, the role of naturally occurring regulatory cells CD4+CD25+Foxp3 + in malaria infection during the disease
Rubika Chauhan, Vikky Awasthi, Reva Sharan Thakur, Veena Pande, Debprasad Chattopadhyay, Jyoti Das   +5 more
doaj   +1 more source