Results 21 to 30 of about 279,153 (249)

CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum

mBio, 2020
The human malaria parasite Plasmodium falciparum uses mutually exclusive expression of the PfEMP1-encoding var gene family to evade the host immune system. Despite progress in the molecular understanding of the default silencing mechanism, the activation
Anna Barcons-Simon, Carlos Cordon-Obras, Julien Guizetti, Jessica M. Bryant, Artur Scherf   +4 more
doaj   +1 more source

Resolving the infection process reveals striking differences in the contribution of environment, genetics and phylogeny to host-parasite interactions [PDF]

, 2011
Background Infection processes consist of a sequence of steps, each critical for the interaction between host and parasite. Studies of host-parasite interactions rarely take into account the fact that different steps might be influenced by different ...
Ebert, Dieter, Dieter Ebert, Ben-Ami, Frida, Laforsch Christian, Duneau David, Ebert Dieter, David Duneau, Laforsch, C., Luijckx Pepijn, Duneau, David, Luijckx, P., Ben-Ami, F., Luijckx, Pepijn, Frida Ben-Ami, Pepijn Luijckx, Duneau, D., Ben-Ami Frida, Christian Laforsch, Laforsch, Christian, Ebert D, Laforsch C, Ben-Ami F, Luijckx P, Duneau D   +23 more
core   +1 more source

The prophenoloxidase system and in vitro interaction of Trypanosoma rangeli with Rhodnius prolixus and Triatoma infestans haemolymph

, 1991
The presence of the prophenoloxidase (proPO) system in the haemolymph of Rhodnius prolixus and Triatoma infestans and the role played by Trypanosoma rangeli in the in vitro activation of proPO were tested. Both R. prolixus and T.
Gregório, E. A., Ratcliffe, N. A.
core   +3 more sources

Biochemical characterization of Plasmodium falciparum parasite specific helicase 1 (PfPSH1)

FEBS Open Bio, 2019
Malaria, a disease caused by infection with parasites of the genus Plasmodium, causes millions of deaths worldwide annually. Of the five Plasmodium species that can infect humans, Plasmodium falciparum causes the most serious parasitic infection.
Manish Chauhan, Suman Sourabh, Rahena Yasmin, Isha Pahuja, Renu Tuteja   +4 more
doaj   +1 more source

Differential expression of immune defences is associated with specific host-parasite interactions in insects [PDF]

, 2009
Recent ecological studies in invertebrates show that the outcome of an infection is dependent on the specific pairing of host and parasite. Such specificity contrasts the long-held view that invertebrate innate immunity depends on a broadspectrum ...
Carolyn Riddell, Riddell, Carolyn, Eamonn B. Mallon (7514327), Adams, Sally, Sally Adams, Schmid-Hempel, Paul, Mallon Eamonn B., Schmid-Hempel Paul, Carolyn Riddell (257705), Paul Schmid-Hempel, S. Adams (1469704), Mallon, Eamonn B., Eamonn B Mallon, Adams Sally, Riddell Carolyn, Ridell, Carolyn, P. Schmid-Hempel (7607216)   +16 more
core   +2 more sources

Parasites

Microbiology Spectrum, 2016
ABSTRACT Parasites are an important cause of human disease worldwide. The clinical severity and outcome of parasitic disease is often dependent on the immune status of the host. Specific parasitic diseases discussed in this chapter are amebiasis, giardiasis, cryptosporidiosis, cyclosporiasis, cystoisosporiasis, microsporidosis, granulomatous ...
Elitza S, Theel, Bobbi S, Pritt
openaire   +2 more sources

Pathophysiology of Cerebral Malaria: Implications of MSCs as A Regenerative Medicinal Tool

Bioengineering, 2022
The severe form of malaria, i.e., cerebral malaria caused by Plasmodium falciparum, is a complex neurological syndrome. Surviving persons have a risk of behavioral difficulties, cognitive disorders, and epilepsy.
Amrendra Chaudhary, Poonam Kataria, Neha Surela, Jyoti Das   +3 more
doaj   +1 more source

microRNAs in parasites and parasite infection [PDF]

RNA Biology, 2013
miRNAs, a subclass of small regulatory RNAs, are present from ancient unicellular protozoans to parasitic helminths and parasitic arthropods. The miRNA-silencing mechanism appears, however, to be absent in a number of protozoan parasites. Protozoan miRNAs and components of their silencing machinery possess features different from other eukaryotes ...
Yadong, Zheng, Xuepeng, Cai, Janette E, Bradley   +2 more
openaire   +2 more sources

Evolutionary analysis of the most polymorphic gene family in falciparum malaria [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research, 2019
The var gene family of the human malaria parasite Plasmodium falciparum encode proteins that are crucial determinants of both pathogenesis and immune evasion and are highly polymorphic.
Thomas D. Otto, Sammy A. Assefa, Ulrike Böhme, Mandy J. Sanders, Dominic Kwiatkowski, Pf3k consortium, Matt Berriman, Chris Newbold   +7 more
doaj   +1 more source

Benefits of host genetic diversity for resistance to infection depend on parasite diversity [PDF]

, 2010
Host populations with high genetic diversity are predicted to have lower levels of infection prevalence. This theory assumes that host genetic diversity results in variation in susceptibility and that parasites exhibit variation in infectivity. Empirical
Ganz, H., Ebert, Dieter, Ganz, Holly H., Ebert D, Ganz HH   +4 more
core   +1 more source