Results 31 to 40 of about 279,153 (249)

CD4+ICOS+Foxp3+: a sub-population of regulatory T cells contribute to malaria pathogenesis

Malaria Journal, 2022
Background Regulatory T cells are known to play a key role to counter balance the protective immune response and immune mediated pathology. However, the role of naturally occurring regulatory cells CD4+CD25+Foxp3 + in malaria infection during the disease
Rubika Chauhan, Vikky Awasthi, Reva Sharan Thakur, Veena Pande, Debprasad Chattopadhyay, Jyoti Das   +5 more
doaj   +1 more source

Variations in the parasite fauna of the three-spined stickleback related to salinity and other parameters [PDF]

, 1972
PhDAlthough the three-spined stickleback Gasterosteus aculeatus L, is a common euryhaline fish, the salinity tolerances of its parasites have not been studied. The present survey was undertaken to remedy this.
Dartnall, Herbert John Graham
core   +2 more sources

Insecticide resistance of Anopheles sinensis after elimination of malaria in Henan Province, China

Parasites & Vectors, 2023
Background Historically, malaria due to Plasmodium vivax has been epidemic in Henan Province, China, with Anopheles sinensis as the main vector. The most effective measures to prevent malaria transmission are based on vector control through the use of ...
Zhi-quan He, Ya-bo Hu, Dan Wang, Yu-ting Liu, Cheng-yun Yang, Dan Qian, Rui-min Zhou, De-ling Lu, Su-hua Li, Ying Liu, Hong-wei Zhang   +10 more
doaj   +1 more source

Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress. [PDF]

, 2013
The malaria parasite replicates within an intraerythrocytic parasitophorous vacuole (PV). Eventually, in a tightly regulated process called egress, proteins of the PV and intracellular merozoite surface are modified by an essential parasite serine ...
Baker, David A, Strath Malcolm, Maria Penzo, David A Baker, Hackett Fiona, Penzo, Maria, Blackman, Michael J, Michael J Blackman, David A. Baker (122252), Christine R Collins, Fiona Hackett (27620), Christine R. Collins, Strath, Malcolm, Withers-Martinez, Chrislaine, David A. Baker, Michael J. Blackman, Malcolm Strath (411645), Withers-Martinez Chrislaine, Penzo Maria, Chrislaine Withers-Martinez, Malcolm Strath, Collins Christine R., Hackett, Fiona, Fiona Hackett, Chrislaine Withers-Martinez (27619), Baker David A., Collins, Christine R, Christine R. Collins (191982), Michael J. Blackman (192013), Blackman Michael J., Maria Penzo (411646)   +30 more
core   +1 more source

The spectrum of clinical biomarkers in severe malaria and new avenues for exploration

Virulence, 2022
Globally, malaria is a public health concern, with severe malaria (SM) contributing a major share of the disease burden in malaria endemic countries. In this context, identification and validation of SM biomarkers are essential in clinical practice. Some
Loick Pradel Kojom Foko, Geetika Narang, Suman Tamang, Joseph Hawadak, Jahnvi Jakhan, Amit Sharma, Vineeta Singh   +6 more
doaj   +1 more source

Estimating malaria parasite density: assumed white blood cell count of 10,000/μl of blood is appropriate measure in Central Ghana. [PDF]

, 2012
BACKGROUND: White blood cells count (WBCc) is a bedrock in the estimation of malaria parasite density in malaria field trials, interventions and patient management.
Mahama, Emmanuel, Kwaku Poku Asante, Adu-Gyasi Dennis, Adu-Gyasi, Dennis, Asante, Kwaku Poku, Adams, Mohammed, Owusu-Agyei, Seth, Seeba Amenga-Etego, Baiden Frank, Nsoh Maxwell, Sam Newton, Newton Sam, Nsoh, Maxwell, Mohammed Adams, Newton, Sam, Amenga-Etego, Seeba, Mahama Emmanuel, Amoako Sabastina, Frank Baiden, Emmanuel Mahama, Baiden, Frank, Seth Owusu-Agyei, Owusu-Agyei Seth, Asante Kwaku, Maxwell Nsoh, Amenga-Etego Seeba, Adams Mohammed, Sabastina Amoako, Amoako, Sabastina, Dennis Adu-Gyasi   +29 more
core   +1 more source

CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum

mBio, 2017
Plasmodium falciparum relies on monoallelic expression of 1 of 60 var virulence genes for antigenic variation and host immune evasion. Each var gene contains a conserved intron which has been implicated in previous studies in both activation and ...
Jessica M. Bryant, Clément Regnault, Christine Scheidig-Benatar, Sebastian Baumgarten, Julien Guizetti, Artur Scherf   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Kinetics of the local cellular response in the gastric lymph of immune and susceptible sheep to infection with Teladorsagia circumcincta [PDF]

, 2009
Groups of yearling sheep were trickle infected with Teladorsagia circumcincta for 8 weeks, then the infection cleared with anthelmintic and both these animals and a group of parasite naïve sheep were challenged with 50 000 infective T.
Halliday, A. M., Morrison, W. I., Smith, W. D., Smith, W.D., Halliday, A.M., Morrison, W.I.   +5 more
core   +1 more source

Comparison of the human-baited double net trap with the human landing catch for Aedes albopictus monitoring in Shanghai, China

Parasites & Vectors, 2018
Background Human landing catch (HLC) is the most efficient method for Aedes monitoring, but it is not ethical due to its high risk of human exposure to pathogens. We designed trials to assess the performance of an alternative human-baited double net trap
Qiang Gao, Fei Wang, Xihong Lv, Hui Cao, Jianjun Zhou, Fei Su, Chenglong Xiong, Peien Leng   +7 more
doaj   +1 more source