Modulation of NF-kappaB activation in Theileria annulata-infected cloned cell lines is associated with detection of parasite-dependent IKK signalosomes and disruption of the actin cytoskeleton [PDF]
, 2010 Apicomplexan parasites within the genus <i>Theileria</i> have the ability to induce continuous proliferation and prevent apoptosis of the infected bovine leukocyte.
Weir, W. +8 more
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Pathophysiology of Cerebral Malaria: Implications of MSCs as A Regenerative Medicinal Tool
Bioengineering, 2022 The severe form of malaria, i.e., cerebral malaria caused by Plasmodium falciparum, is a complex neurological syndrome. Surviving persons have a risk of behavioral difficulties, cognitive disorders, and epilepsy.
Amrendra Chaudhary +3 more
doaj +1 more source
Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress. [PDF]
, 2013 The malaria parasite replicates within an intraerythrocytic parasitophorous vacuole (PV). Eventually, in a tightly regulated process called egress, proteins of the PV and intracellular merozoite surface are modified by an essential parasite serine ...
Baker, David A +30 more
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Microbiology Spectrum, 2016 ABSTRACT Parasites are an important cause of human disease worldwide. The clinical severity and outcome of parasitic disease is often dependent on the immune status of the host. Specific parasitic diseases discussed in this chapter are amebiasis, giardiasis, cryptosporidiosis, cyclosporiasis, cystoisosporiasis, microsporidosis, granulomatous ...
Elitza S, Theel, Bobbi S, Pritt
openaire +2 more sources
microRNAs in parasites and parasite infection [PDF]
RNA Biology, 2013 miRNAs, a subclass of small regulatory RNAs, are present from ancient unicellular protozoans to parasitic helminths and parasitic arthropods. The miRNA-silencing mechanism appears, however, to be absent in a number of protozoan parasites. Protozoan miRNAs and components of their silencing machinery possess features different from other eukaryotes ...
Yadong, Zheng +2 more
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Resolving the infection process reveals striking differences in the contribution of environment, genetics and phylogeny to host-parasite interactions [PDF]
, 2011 Background Infection processes consist of a sequence of steps, each critical for the interaction between host and parasite. Studies of host-parasite interactions rarely take into account the fact that different steps might be influenced by different ...
Ebert, Dieter +18 more
core +1 more source
Wellcome Open Research, 2019 The var gene family of the human malaria parasite Plasmodium falciparum encode proteins that are crucial determinants of both pathogenesis and immune evasion and are highly polymorphic.
Thomas D. Otto +7 more
doaj +1 more source
CD4+ICOS+Foxp3+: a sub-population of regulatory T cells contribute to malaria pathogenesis
Malaria Journal, 2022 Background Regulatory T cells are known to play a key role to counter balance the protective immune response and immune mediated pathology. However, the role of naturally occurring regulatory cells CD4+CD25+Foxp3 + in malaria infection during the disease
Rubika Chauhan +5 more
doaj +1 more source
Dietary supply with polyunsaturated fatty acids and resulting maternal effects influence host -- parasite interactions [PDF]
, 2013 Interactions between hosts and parasites can be substantially modulated by host nutrition. Polyunsaturated fatty acids (PUFAs) are essential dietary nutrients; they are indispensable as structural components of cell membranes and as precursors for ...
Ebert, Dieter +5 more
core +1 more source
Prospective identification of malaria parasite genes under balancing selection. [PDF]
, 2009 BACKGROUND: Endemic human pathogens are subject to strong immune selection, and interrogation of pathogen genome variation for signatures of balancing selection can identify important target antigens.
Conway, David J +31 more
core +1 more source