Results 1 to 10 of about 60,049 (296)

Biological and Molecular Characterization of Five Trypanosoma cruzi (Chagas, 1909) (Kinetoplastida, Trypanosomatidae) Isolates from the State of Hidalgo, Mexico [PDF]

Tropical Medicine and Infectious Disease
Trypanosoma cruzi, the causal agent of Chagas disease, exhibits great genetic diversity, which has been related to its biological properties. However, these are poorly known in strains from the endemic area of Hidalgo. To assess the parasite’s virulence,
Yessenia Montes-Vergara, Alberto Antonio-Campos, José Miguel Padilla-Valdez, Erick Abraham Contreras-López, Julio Cesar Noguez-García, Nancy Rivas, Ricardo Alejandre-Aguilar   +6 more
doaj   +2 more sources

Reciprocal positive effects on parasitemia between coinfecting haemosporidian parasites in house sparrows

BMC Ecology and Evolution, 2022
Background Hosts are often simultaneously infected with several parasite species. These co-infections can lead to within-host interactions of parasites, including mutualism and competition, which may affect both virulence and transmission.
L. García‐Longoria, S. Magallanes, Xi Huang, A. Drews, L. Råberg, A. Marzal, S. Bensch, H. Westerdahl   +7 more
semanticscholar   +1 more source

Epidemiological characteristics of P. vivax asymptomatic infections in the Peruvian Amazon

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionHerein, we tested the hypothesis that Asymptomatic P. vivax (Pv) infected individuals (Asym) feature different epidemiological, clinical and biochemical characteristics, as well as hematological parameters, potentially predictive of clinical ...
Elizabeth Villasis, Elizabeth Villasis, Stefano S. Garcia Castillo, Mitchel Guzman, Mitchel Guzman, Julian Torres, Joaquin Gomez, Katherine Garro, Ana Maria Cordova, Carolina Reategui, Caroline Abanto, Joseph Vinetz, Joseph Vinetz, Dionicia Gamboa, Dionicia Gamboa, Dionicia Gamboa, Katherine Torres, Katherine Torres   +17 more
doaj   +1 more source

PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controlled human malaria infection

PLoS Pathogens, 2021
PfSPZ-CVac combines ‘PfSPZ Challenge’, which consists of infectious Plasmodium falciparum sporozoites (PfSPZ), with concurrent antimalarial chemoprophylaxis.
S. Murphy, G. Deye, B. Sim, S. Galbiati, J. Kennedy, Kristen W. Cohen, S. Chakravarty, Natasha K C, Y. Abebe, E. James, J. Kublin, S. Hoffman, T. Richie, L. Jackson   +13 more
semanticscholar   +1 more source

Annona muricata Linn and Khaya grandifoliola C.DC. Reduce Oxidative Stress In Vitro and Ameliorate Plasmodium berghei-Induced Parasitemia and Cytokines in BALB/c Mice

Journal of Evidence-Based Integrative Medicine, 2021
Background. Annona muricata and Khaya grandifoliola are ethnomedicinally used for the treatment of malaria and have been experimentally shown to have an anti-plasmodial effect, but the mechanisms involved are not fully understood. This study investigated
H. Onohuean, A. Alagbonsi, I. Usman, Keneth Iceland Kasozi, A. Alexiou, R. Badr, G. Batiha, Joseph O. C. Ezeonwumelu   +7 more
semanticscholar   +1 more source

How to improve the early diagnosis of Trypanosoma cruzi infection: Relationship between validated conventional diagnosis and quantitative DNA amplification in congenitally infected children [PDF]

, 2013
BACKGROUND: According to the Chagas congenital transmission guides, the diagnosis of infants, born to Trypanosoma cruzi infected mothers, relies on the detection of parasites by INP micromethod, and/or the persistence of T. cruzi specific antibody titers
Bua, Jacqueline Elena, Cardoni, Rita Liliana, de Rissio, Ana María, Perrone, Alina Elizabeth, Ruiz, Andrés Mariano, Scollo, Karenina, Velázquez, Elsa Beatriz, Volta, Bibiana Julieta   +7 more
core   +7 more sources

Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]

, 2020
Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan, Obishakin, Emmanuel Tumininu, Pinto Torres, Joar Esteban, Radwanska, Magdalena   +3 more
core   +1 more source

Increased tumor necrosis factor alpha and interleukin-6 serum levels and their correlation with laboratory parameters in patients with imported malaria [PDF]

Archives of Biological Sciences, 2012
In malaria, blood concentrations of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-α) and interleukin (IL)-6, are increased. In a study which included 34 patients, TNF-α and IL-6 were examined in two phases, immediately after the ...
Poluga Jasmina, Dopsaj Violeta, Veljković Milena, Maksić N., Stojaković Sonja, Dunjić Radica, Dakić Zorica, Pavlović Milorad   +7 more
doaj   +1 more source

Mannose inhibits Plasmodium parasite growth and cerebral malaria development via regulation of host immune responses

Frontiers in Immunology, 2022
D-mannose can be transported into a variety of cells via glucose transporter (GLUT), and supraphysiological levels of D-mannose impairs tumor growth and modulates immune cell function through mechanisms such as interference with glycolysis and induction ...
Li Lv, Zihao Xu, Meichen Zhao, Jian Gao, Rumeng Jiang, Qian Wang, Qian Wang, Xiaoyu Shi   +7 more
doaj   +1 more source

Trypanosoma brucei brucei is more pathogenic in rats compared to mice, making rats a better candidate for the relevant research studies [PDF]

The Iranian Journal of Veterinary Science and Technology, 2021
Trypanosomosis is an economically important disease that has raised great and diverse kinds of research using different types of animals. Hence, this study is aimed at determining the better laboratory animal between the Swiss albino mice and Wistar ...
Karimat Hussain, Shola Ola-Fadunsin, Idris Lawal, Sani Adamu, Saliu Ameen   +4 more
doaj   +1 more source