Results 31 to 40 of about 60,049 (296)

Efektivitas Kombinasi Artesunat-Klindamisin dengan Kinin-Klindamisin pada Pengobatan Malaria FalciparumTanpa Komplikasi pada Anak

open access: yesSari Pediatri, 2016
Latar belakang. Kombinasi antimalaria termasuk artemisinin sering tidak sesuai secara farmakokinetika sehingga berpotensi untuk resistensi. Untuk itu penilaian terhadap kombinasi artemisinin dengan obat yang mempunyai waktu paruh yang pendek diperlukan
Erika S. Panjaitan   +5 more
doaj   +1 more source

Rocaglates as dual-targeting agents for experimental cerebral malaria [PDF]

open access: yes, 2018
Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity.
Ayi, Kodjo   +12 more
core   +1 more source

The Consequences of Treating Asymptomatic Malaria Parasitemia [PDF]

open access: yesClinical Infectious Diseases, 2017
Editorial Commentary: Immunity to malaria is hard won and yet it is imperfect.
openaire   +4 more sources

Analysis of slow (theta) oscillations as a potential temporal reference frame for information coding in sensory cortices [PDF]

open access: yes, 2012
While sensory neurons carry behaviorally relevant information in responses that often extend over hundreds of milliseconds, the key units of neural information likely consist of much shorter and temporally precise spike patterns.
Christoph Kayser   +3 more
core   +3 more sources

Biannual mass azithromycin distributions and malaria parasitemia in pre-school children in Niger: A cluster-randomized, placebo-controlled trial

open access: yesPLoS Medicine, 2019
Background Mass azithromycin distributions have been shown to reduce mortality in preschool children, although the factors mediating this mortality reduction are not clear.
Ahmed M. Arzika   +12 more
semanticscholar   +1 more source

Quantitative Detection of Plasmodium falciparum Using, LUNA-FL, A Fluorescent Cell Counter

open access: yesMicroorganisms, 2020
The microscopic examination of Giemsa-stained thin and/or thick blood films (Giemsa microscopy) is the standard method of malaria diagnosis. However, the results of the diagnosis significantly depend on the skills of clinical technicians.
Muneaki Hashimoto   +11 more
doaj   +1 more source

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]

open access: yes, 2016
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida   +48 more
core   +2 more sources

Impact of microscopic and submicroscopic parasitemia during pregnancy on placental malaria in a high-transmission setting in Uganda.

open access: yesJournal of Infectious Diseases, 2019
BACKGROUND Placental malaria is a major cause of adverse birth outcomes. However, data are limited on the relationships between longitudinal measures of parasitemia during pregnancy and placental malaria.
J. Briggs   +11 more
semanticscholar   +1 more source

The role of submicroscopic parasitemia in malaria transmission: what is the evidence?

open access: yesTrends in Parasitology, 2014
Achieving malaria elimination requires targeting the human reservoir of infection, including those with asymptomatic infection. Smear-positive asymptomatic infections detectable by microscopy are an important reservoir because they often persist for months and harbor gametocytes, the parasite stage infectious to mosquitoes.
Jessica T. Lin, D. Saunders, S. Meshnick
semanticscholar   +4 more sources

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

open access: yesAngewandte Chemie, EarlyView.
AZD0156, an ATM kinase inhibitor in clinical development, shows promising multistage antiplasmodial activity by targeting Plasmodium falciparum phosphatidylinositol 4‐kinase (PfPI4Kβ). With an improved specificity profile relative to other PfPI4Kβ inhibitors and moderate efficacy in a P.
John G. Woodland   +33 more
wiley   +2 more sources

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