Results 41 to 50 of about 774,131 (288)

Identification of cutaneous fungi and mites in adult atopic dermatitis: analysis by targeted 18S rRNA amplicon sequencing

open access: yesBMC Microbiology, 2021
Background Atopic dermatitis (AD) patients have an altered skin bacterial community, with an abundance of Staphylococcus aureus associated with flares, highlighting that microbial organisms may be important for disease exacerbation.
Sofie Marie Edslev   +6 more
doaj   +1 more source

Effects of Ostertagia circumcincta larvae and adult parasites on abomasal and intestinal tissues in sheep : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology [PDF]

open access: yes, 1994
Ostertagia circumcincta parasites infect the abomasum of sheep causing damage to the abomasal tissues and significant production losses to the sheep farming industry.
Hodgkinson, Suzanne Marie
core  

Crowdsourcing malaria parasite quantification: an online game for analyzing images of infected thick blood smears [PDF]

open access: yes, 2012
Background: There are 600,000 new malaria cases daily worldwide. The gold standard for estimating the parasite burden and the corresponding severity of the disease consists in manually counting the number of parasites in blood smears through a microscope,
Abt, C   +10 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

High quality transcriptome profiling confirms the transcriptional landscape of Treponema pallidum subsp. pallidum

open access: yesScientific Reports
Syphilis remains a critical global health challenge due to its potential for severe complications and the increase in its incidence rate over recent years. Until recently, the infectious agent of syphilis, Treponema pallidum subsp.
Linda Grillová   +3 more
doaj   +1 more source

GeneDB and Wikidata [version 2; peer review: 2 approved]

open access: yesWellcome Open Research, 2019
Publishing authoritative genomic annotation data, keeping it up to date, linking it to related information, and allowing community annotation is difficult and hard to support with limited resources. Here, we show how importing GeneDB annotation data into
Magnus Manske   +3 more
doaj   +1 more source

The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]

open access: yes, 2019
Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K.   +2 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Molecular characterization and epidemiology of Streptococcus pneumoniae serotype 8 in Denmark

open access: yesBMC Infectious Diseases, 2021
Background Streptococcus pneumoniae serotype 8 incidence has increased in Denmark after the introduction of pneumococcal conjugated vaccines (PCV). The mechanism behind the serotype 8 replacement is not well understood. In this study, we aimed to present
Camilla Bülow Hansen   +5 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

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