Results 21 to 30 of about 965 (154)
Advanced Functional Materials, Volume 35, Issue 23, June 5, 2025.Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong +7 more
wiley +1 more source
Epilepsia, Volume 66, Issue 4, Page 1329-1342, April 2025.Abstract Objective Acute organophosphate (OP) intoxication affects a significant number of individuals worldwide. Those who survive OP‐induced cholinergic crisis, which includes status epilepticus, often develop neurological morbidities. Here, we provide a rigorous characterization of the acute and delayed electrophysiological responses to OP ...
Jeremy A. MacMahon +8 more
wiley +1 more source
Pulverized Oral Nicotine Equivalent to One Cigarrette Reduces Parasympathomimetic Neurovegetative Tone and Increases the Physical Dependence in Smokers [PDF]
, 2021 Pascual Susana Calvo +2 more
openalex +1 more source
Journal of Pineal Research, Volume 77, Issue 3, April 2025.ABSTRACT Melatonin synthesis by yeast has been described on several occasions, mainly in a fermentative context. However, the genetic determinants involved in its synthesis remain undefined. Understanding melatonin synthesis in yeast is important because it can provide insights into the broader mechanisms of indolamine production, which has ...
Andrés Planells‐Cárcel +3 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 3, March 2025.Acute poisoning with the organophosphate, soman, triggers status epilepticus that rapidly becomes refractory to standard of care treatment with midazolam (MDZ). Combined treatment with MDZ and allopregnanolone (ALLO) significantly suppresses seizure activity, which is associated with attenuated neurodegeneration and neuroinflammation.
Peter M. Andrew +10 more
wiley +1 more source
Bayliss Starling Prize Lecture 2023: Neuropeptide‐Y being ‘unsympathetic’ to the broken hearted
The Journal of Physiology, Volume 603, Issue 7, Page 1841-1864, 31 March 2025.Abstract figure legend The hallmark of cardiac disease is autonomic dysregulation, characterised by a state of chronic sympathoexcitation. Neuropeptide‐Y (NPY) is a sympathetic co‐transmitter that is released by sympathetic neurons and circulating venous levels are elevated in a range of cardiac disease, such as myocardial infarction and chronic heart ...
Benjamin Bussmann +4 more
wiley +1 more source
The Journal of Physiology, Volume 603, Issue 7, Page 1865-1885, 31 March 2025.Abstract figure legend Summary of strategies in modelling neurocardiac interactions using human pluripotent stem cells. Abstract Throughout our lifetime the heart executes cycles of contraction and relaxation to meet the body's ever‐changing metabolic needs. This vital function is continuously regulated by the autonomic nervous system.
Hsueh‐Fu Wu +4 more
wiley +1 more source
Angewandte Chemie International Edition, Volume 63, Issue 52, December 20, 2024.l‐(+)‐Muscarine is one of the most toxic mushroom metabolites. We identified its congener 4’‐phosphomuscarine in the fool's funnel and in various fiber cap mushrooms, and chemically and pharmacologically characterized this new natural product. As hydrolysis of its ester releases muscarine, our results help estimate the true toxin content of these ...
Sebastian Dörner +7 more
wiley +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 23, Issue 6, November 2024.Abstract Food safety is crucial to attaining food security and sustainability. Unsafe foods for human and animal consumption lead to product recalls and rejection, negatively impacting the global economy and trade. Similarly, climate change can adversely affect the availability of safe and nutritious food at the table.
Rufielyn S. Gravador +6 more
wiley +1 more source
Topical glaucoma medications − Possible implications on the meibomian glands
Acta Ophthalmologica, Volume 102, Issue 7, Page 735-748, November 2024.Abstract One of the most common causes of blindness on a global scale is glaucoma. There is a strong association between glaucoma and increased intraocular pressure (IOP). Because of this, adequate IOP‐lowering is the most important treatment strategy, mostly through topical eyedrops.
Fredrik Fineide +6 more
wiley +1 more source