Results 41 to 50 of about 2,092 (204)

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

ChemistryEurope, Volume 3, Issue 4, July 14, 2025.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

Butorphanol or a Combination of Ketamine and Xylazine Do Not Interfere With Arrhythmogenic Parameters in Agoutis (Dasyprocta prymnolopha) Obtained Through High‐Resolution Electrocardiogram

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 343, Issue 6, Page 693-702, July 2025.
ABSTRACT Introduction/Objectives: Agoutis is a medium‐sized wild rodent with potential for use as an experimental model. This study aimed to evaluate physiological parameters of arrhythmogenesis in this species, by HR‐ECG and VCG techniques, under physical and pharmacological containment (ketamine‐xylazine and butorphanol). Materials and methods: Eight
Charlys Rhands Coelho de Moura, Hermínio José da Rocha Neto, Regina Lucia dos Santos Silva, Nayla Maria da Silva Rezende Amorim, José Lindenberg Rocha Sarmento, Miguel Ferreira Cavalcante Filho, Wanderson Gabriel Gomes de Melo, Dayseanny de Oliveira Bezerra, Maria Acelina Martins Carvalho, Napoleão Martins Argolo Neto   +9 more
wiley   +1 more source

Male infertility [PDF]

, 2012
published_or_final_versio
Ho, PC, Lee, VCY, Ng, EHY
core  

Feed‐induced hypersalivation in horses from Austria, Germany and Switzerland

Equine Veterinary Journal, Volume 57, Issue 4, Page 1035-1043, July 2025.
Abstract Background While previous reports come mostly from the southern Americas, several outbreaks of hypersalivation in horses were observed in Middle Europe from 2016 to 2018. Objective To describe feed‐induced hypersalivation in European horses. Study design Analysis of feedstuffs.
Linda Franziska Böswald, Christoph Gottschalk, Florian Kaltner, Joana Merk, Karin Schwaiger, Ellen Kienzle   +5 more
wiley   +1 more source

Characteristics of Drug Poisonings Presenting to the Emergency Department: An Electronic Medical Record Database Analysis [PDF]

, 2021
Rationale: Drug poisonings are a frequent diagnosis in the Emergency Department (ED), requiring patient management from multiple services. Although there is considerable research detailing the fatal opioid overdose epidemic, little is known about drug ...
Bell, Matthew, Hanel, Erich, Holbrook, Anne, Rigg, Kaitlynn, Wallace, Christine   +4 more
core  

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

Advanced Functional Materials, Volume 35, Issue 23, June 5, 2025.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Seon Yeong Chae, Min Jae Kim, Ki Jun Yu, Hwa Kyoung Shin, Suck Won Hong   +7 more
wiley   +1 more source

Acute and persistent changes in neural oscillatory activity predict development of epilepsy following acute organophosphate intoxication in adult rats

Epilepsia, Volume 66, Issue 4, Page 1329-1342, April 2025.
Abstract Objective Acute organophosphate (OP) intoxication affects a significant number of individuals worldwide. Those who survive OP‐induced cholinergic crisis, which includes status epilepticus, often develop neurological morbidities. Here, we provide a rigorous characterization of the acute and delayed electrophysiological responses to OP ...
Jeremy A. MacMahon, Peter M. Andrew, Ali Izadi, Donald A. Bruun, Naomi H. Saito, Daniel J. Tancredi, Amy Brooks‐Kayal, Pamela J. Lein, Gene G. Gurkoff   +8 more
wiley   +1 more source

IAT4, a New Indolamine N‐Acetyltransferase in Saccharomyces cerevisiae Involved in Melatonin Biosynthesis

Journal of Pineal Research, Volume 77, Issue 3, April 2025.
ABSTRACT Melatonin synthesis by yeast has been described on several occasions, mainly in a fermentative context. However, the genetic determinants involved in its synthesis remain undefined. Understanding melatonin synthesis in yeast is important because it can provide insights into the broader mechanisms of indolamine production, which has ...
Andrés Planells‐Cárcel, Sandra Sánchez‐Martí, Sara Muñiz‐Calvo, José Manuel Guillamon   +3 more
wiley   +1 more source

Comparison of Fissure Healing and The Incidence of Headache Among the Patients Treated with Endo- and Perianal Application of 0.2% Glyceryl Trinitrate for Chronic Anal Fissure [PDF]

, 2016
Introduction: Chronic anal fissure is associated with significant morbidity and reduction in quality of life mostly in young healthy adults. Glyceryl Trinitrate, a most commonly used agent for treatment, is associated with incidence of headache causing ...
Mukund Raj Joshi, Shail Rupakheti, Tanka Prasad Bohara   +2 more
core   +2 more sources

Allopregnanolone as an Adjunct Therapy to Midazolam is More Effective Than Midazolam Alone in Suppressing Soman‐Induced Status Epilepticus in Male Rats

CNS Neuroscience &Therapeutics, Volume 31, Issue 3, March 2025.
Acute poisoning with the organophosphate, soman, triggers status epilepticus that rapidly becomes refractory to standard of care treatment with midazolam (MDZ). Combined treatment with MDZ and allopregnanolone (ALLO) significantly suppresses seizure activity, which is associated with attenuated neurodegeneration and neuroinflammation.
Peter M. Andrew, Jeremy A. MacMahon, Xiuzhen Liu, Naomi H. Saito, Kyle E. Berger, Julia E. Morgan, Ashish Dhir, Danielle J. Harvey, Hilary S. McCarren, Michael A. Rogawski, Pamela J. Lein   +10 more
wiley   +1 more source