Results 41 to 50 of about 2,106 (208)

Feed‐induced hypersalivation in horses from Austria, Germany and Switzerland

open access: yesEquine Veterinary Journal, Volume 57, Issue 4, Page 1035-1043, July 2025.
Abstract Background While previous reports come mostly from the southern Americas, several outbreaks of hypersalivation in horses were observed in Middle Europe from 2016 to 2018. Objective To describe feed‐induced hypersalivation in European horses. Study design Analysis of feedstuffs.
Linda Franziska Böswald   +5 more
wiley   +1 more source

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

open access: yesAdvanced Functional Materials, Volume 35, Issue 23, June 5, 2025.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong   +7 more
wiley   +1 more source

Characteristics of Drug Poisonings Presenting to the Emergency Department: An Electronic Medical Record Database Analysis [PDF]

open access: yes, 2021
Rationale: Drug poisonings are a frequent diagnosis in the Emergency Department (ED), requiring patient management from multiple services. Although there is considerable research detailing the fatal opioid overdose epidemic, little is known about drug ...
Bell, Matthew   +4 more
core  

Acute and persistent changes in neural oscillatory activity predict development of epilepsy following acute organophosphate intoxication in adult rats

open access: yesEpilepsia, Volume 66, Issue 4, Page 1329-1342, April 2025.
Abstract Objective Acute organophosphate (OP) intoxication affects a significant number of individuals worldwide. Those who survive OP‐induced cholinergic crisis, which includes status epilepticus, often develop neurological morbidities. Here, we provide a rigorous characterization of the acute and delayed electrophysiological responses to OP ...
Jeremy A. MacMahon   +8 more
wiley   +1 more source

IAT4, a New Indolamine N‐Acetyltransferase in Saccharomyces cerevisiae Involved in Melatonin Biosynthesis

open access: yesJournal of Pineal Research, Volume 77, Issue 3, April 2025.
ABSTRACT Melatonin synthesis by yeast has been described on several occasions, mainly in a fermentative context. However, the genetic determinants involved in its synthesis remain undefined. Understanding melatonin synthesis in yeast is important because it can provide insights into the broader mechanisms of indolamine production, which has ...
Andrés Planells‐Cárcel   +3 more
wiley   +1 more source

Allopregnanolone as an Adjunct Therapy to Midazolam is More Effective Than Midazolam Alone in Suppressing Soman‐Induced Status Epilepticus in Male Rats

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 3, March 2025.
Acute poisoning with the organophosphate, soman, triggers status epilepticus that rapidly becomes refractory to standard of care treatment with midazolam (MDZ). Combined treatment with MDZ and allopregnanolone (ALLO) significantly suppresses seizure activity, which is associated with attenuated neurodegeneration and neuroinflammation.
Peter M. Andrew   +10 more
wiley   +1 more source

Comparison of Fissure Healing and The Incidence of Headache Among the Patients Treated with Endo- and Perianal Application of 0.2% Glyceryl Trinitrate for Chronic Anal Fissure [PDF]

open access: yes, 2016
Introduction: Chronic anal fissure is associated with significant morbidity and reduction in quality of life mostly in young healthy adults. Glyceryl Trinitrate, a most commonly used agent for treatment, is associated with incidence of headache causing ...
Mukund Raj Joshi   +2 more
core   +2 more sources

Bayliss Starling Prize Lecture 2023: Neuropeptide‐Y being ‘unsympathetic’ to the broken hearted

open access: yesThe Journal of Physiology, Volume 603, Issue 7, Page 1841-1864, 31 March 2025.
Abstract figure legend The hallmark of cardiac disease is autonomic dysregulation, characterised by a state of chronic sympathoexcitation. Neuropeptide‐Y (NPY) is a sympathetic co‐transmitter that is released by sympathetic neurons and circulating venous levels are elevated in a range of cardiac disease, such as myocardial infarction and chronic heart ...
Benjamin Bussmann   +4 more
wiley   +1 more source

Modelling neurocardiac physiology and diseases using human pluripotent stem cells: current progress and future prospects

open access: yesThe Journal of Physiology, Volume 603, Issue 7, Page 1865-1885, 31 March 2025.
Abstract figure legend Summary of strategies in modelling neurocardiac interactions using human pluripotent stem cells. Abstract Throughout our lifetime the heart executes cycles of contraction and relaxation to meet the body's ever‐changing metabolic needs. This vital function is continuously regulated by the autonomic nervous system.
Hsueh‐Fu Wu   +4 more
wiley   +1 more source

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