Results 121 to 130 of about 115,825 (254)

Different parts of the mussel Gigantidas haimaensis holobiont responded differently to deep‐sea sampling stress

open access: yesIntegrative Zoology, EarlyView.
Symbiotic gill and nonsymbiotic mantle of mussel Gigantidas haimaensis responded differently to deep‐sea sampling stress caused by acute environmental changes. Sharply increased transcription factors potentially play key roles in initiating the response of sampled deep‐sea macrobenthos to the sampling stress.
Guoyong YAN   +4 more
wiley   +1 more source

Organ Specificity and Commonality of Epigenetic Aging in Low‐ and High‐Running Capacity Rats

open access: yesAging Cell, EarlyView.
Cardiorespiratory fitness (CRF) is not associated with epigenetic clocks, including newly developed ones. On the other hand, CRF is associated with global methylation profiles and promoter methylation in organ‐specific and organ‐common manner. ABSTRACT Epigenetic drift, which is gradual age‐related changes in DNA methylation patterns, plays a ...
Takuji Kawamura   +15 more
wiley   +1 more source

Parathyroid Adenoma in a Child Presenting as Rickets [PDF]

open access: bronze, 1958
B. S. B. Wood   +2 more
openalex   +1 more source

Circadian Gene BMAL1 Regulation of Cellular Senescence in Thyroid Aging

open access: yesAging Cell, EarlyView.
BMAL1 downregulation during aging reduces NFKBIA expression, accelerating thyroid cellular senescence and impairing hormone synthesis. Circadian rhythm disruption exacerbates thyroid functional decline, highlighting the BMAL1‐NFKBIA axis as a key mediator of aging‐related thyroid dysfunction and offering insights for stabilizing thyroid health in aging
Dandan Zong   +4 more
wiley   +1 more source

Safety concerns of paternal drug exposure on fertility, pregnancy and offspring: An analysis based on the FDA adverse event reporting system

open access: yesAndrology, EarlyView.
Abstract Background Growing evidence indicates that paternal condition significantly influences pregnancy outcomes and offspring health. However, assessing the safety of paternal drug exposure via randomized controlled trials poses ethical challenges, and relevant clinical studies consume a lot of resources to evaluate only a few drugs.
Yanbin Zeng, Wanlong Lin, Wei Zhuang
wiley   +1 more source

Stroke Mimicking Thalamotomy in Primary Familial Brain Calcification

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Jaakko Kungshamn   +4 more
wiley   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

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