Results 21 to 30 of about 43,074 (235)

Mutations of the ret protooncogene in German multiple endocrine neoplasia families: Relation between genotype and phenotype. [PDF]

, 1996
It has been suggested that not only the position but also the nature of the mutations of the ret protooncogene strongly correlate with the clinical manifestation of the multiple endocrine neoplasm type 2 (MEN 2) syndrome.
Deckart, H. F., Dralle, H., Frank-Raue, K., Frilling, A., Haase, R., Hampel, R., Höppner, W., Kirchner, R., Klempa, J., Kotzerke, J., Mann, K., Raue, F., Rendl, J., Ritter, M. M., Scholz, G. H., Seif, F.   +15 more
core   +1 more source

Two case reports of parathyroid carcinoma and review of the literature

Journal of Oncological Sciences, 2017
Parathyroid carcinoma is an infrequent endocrine malignant neoplasm with an aggressive behavior. Two cases of parathyroid carcinoma are described, one with a late diagnosis after previous surgeries for parathyroid hyperplasia, and the other diagnosed ...
Juliana Maria de Almeida Vital, Terence Pires de Farias, Fernanda Vaisman, Juliana Fernandes, Arli Regina Lopes Moraes, Paulo José de Cavalcanti Siebra, José Gabriel Miranda da Paixão   +6 more
doaj   +1 more source

Parathyroid carcinoma in a 13-year-old girl with a long-term survival

Surgical Case Reports, 2020
Background Parathyroid carcinoma as a cause of primary hyperparathyroidism in children is extremely rare. We report a case of parathyroid carcinoma which occurred in a 13-year-old girl who survived for more than 45 years after the first operation.
Yoko Omi, Tomoko Yamamoto, Yoji Nagashima, Koichiro Abe, Kumiko Karasawa, Yukichi Tanaka, Takahiro Okamoto   +6 more
doaj   +1 more source

Metastatic parathyroid carcinoma: A tale of refractory hypercalcemia

Journal of Clinical and Translational Endocrinology Case Reports, 2023
Background/objective: Parathyroid carcinoma is a rare entity presenting as parathyroid hormone (PTH) dependent hypercalcemia. Our objective was to report a case of metastatic parathyroid carcinoma in a middle-aged woman, who presented with refractory ...
Johns T. Johnson, Arun George, Junita Rachel John, Nishok David, Ashish Singh, Deepak Abraham, Birla Roy Gnanamuthu, Nihal Thomas   +7 more
doaj   +1 more source

The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]

, 2013
The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves, D'Herde, Katharina, Diez Fraile, Araceli, Lammens, Tim   +3 more
core   +1 more source

Hypopituitarism due to a Large Osteoclastoma Arising from the Sphenoid Bone Invading the Pituitary Fossa in a Patient with Parathyroid Carcinoma

Case Reports in Endocrinology, 2023
Background. Parathyroid carcinoma accounts for
Leonardo Bandeira, Lucian Batista de Oliveira, Maria Vitória Silva de Lima, Daniella Rêgo, Luiz Griz, Francisco Bandeira   +5 more
doaj   +1 more source

Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]

, 2013
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher, Solomon, Daniel, Sosa, Julie Ann, Tuggle, Charles   +3 more
core   +1 more source

Radiation-Induced Synchronous Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Clinical, Morphological, and Genetic Insights. [PDF]

Int J Mol Sci
Iványi G, Christofi A, Sipka G, Zombori T, Kuthi L, Simon A, Dobi D, Lázár G, Valkusz Z, Iványi B.   +9 more
europepmc   +3 more sources

PIK3CA Mutational Analysis of Parathyroid Adenomas

JBMR Plus, 2020
Benign parathyroid adenoma is the most common cause of primary hyperparathyroidism, whereas malignant parathyroid carcinoma is exceedingly rare. Distinguishing parathyroid carcinoma from benign adenoma is often difficult, and may be considerably delayed ...
Aaliyah Riccardi, Carolina Lemos, Ryan Ramos, Justin Bellizzi, Kourosh Parham, Taylor C. Brown, Reju Korah, Tobias Carling, Jessica Costa‐Guda, Andrew Arnold   +9 more
doaj   +1 more source

Utility of 99mTc-Sestamibi SPECT/CT in the Early Localization of Metastatic Parathyroid Carcinoma [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2018
Parathyroid carcinoma is very rare, with only a few documented cases. Hence, metastatic lesions are infrequently documented on scintigraphic imaging. We present a case of a 63-year-old female presenting with elevated serum levels of ionized calcium and ...
Patrick Earl Fernando, Patricia Bautista
doaj   +1 more source