Results 91 to 100 of about 44,736 (232)

Inflammatory and Immunological Basis of Periodontal Diseases

open access: yesJournal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima   +3 more
wiley   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

open access: yesJournal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang   +3 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Parathyroid hormone-related protein activates HSCs via hedgehog signalling during liver fibrosis development

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Recently, we showed that parathyroid hormone-like hormone (PTHLH), a cytokine-like polyprotein, is critical for extracellular matrix (ECM) deposition through the activation of hepatic stellate cells (HSCs). Here, we show that N-terminal PTHLH is secreted
Shuying He   +7 more
doaj   +1 more source

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park   +5 more
wiley   +1 more source

Parathyroid Hormone Related Protein in Hypercalcemia Malignancies [PDF]

open access: yes
Background: Paraneoplastic syndromes encompass symptoms or signs caused by malignant tumors through humoral factors, such as hormones or cytokines, produced by tumor cells.
Suharto, Fadel Fikri   +1 more
core   +2 more sources

PTHLH (parathyroid hormone-like hormone) [PDF]

open access: yes, 2013
Review on PTHLH (parathyroid hormone-like hormone), with data on DNA, on the protein encoded, and where the gene is ...
Habra, MA, Yeung, SCJ
core   +1 more source

Induced Pluripotent Stem Cell‐Derived Parathyroid Organoids Resemble Parathyroid Morphology and Function

open access: yesAdvanced Science
The primary role of the parathyroid glands is to maintain calcium homeostasis through the secretion of parathyroid hormone (PTH). The limited proliferative capacity and differentiation of parathyroid cells hinder the generation of cell therapy options ...
Selinay Şenkal‐Turhan   +8 more
doaj   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

open access: yesPeriodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron   +8 more
wiley   +1 more source

Parathyroid hormone receptors in GtoPdb v.2025.3 [PDF]

open access: yes
The parathyroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Parathyroid Hormone Receptors [50]) are class B G protein-coupled receptors.
Vilardaga, Jean-Pierre   +11 more
core   +2 more sources

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