Results 31 to 40 of about 121,783 (270)
SAGE Open Medical Case Reports, 2022 We report on the case of a patient with dysgerminoma, a rare germ cell tumor, which showed hypercalcemia with an elevation of 1α,25-dihydroxycholecalciferol (calcitriol). A 27-year-old nulliparous woman presented with hypercalcemia during the examination
Natsuko Hara +11 more
doaj +1 more source
Multiple actions of parathyroid hormone‐related protein in breast cancer bone metastasis
British Journal of Pharmacology, 2019 The sequence similarity within the amino‐terminal regions of parathyroid hormone (PTH) and PTH‐related protein (PTHrP) allows the two to share actions at a common site, the PTH1 receptor. A number of biological activities have been ascribed to actions of
T. Martin, Rachelle W. Johnson
semanticscholar +1 more source
Journal of Medical Case Reports, 2010 Introduction Hypercalcemia is the major electrolyte abnormality in patients with malignant tumors. It can be due to localized osteolytic hypercalcemia or elaboration of humoral substances such as parathyroid hormone-related protein from tumoral cells. In
Tirgari Farrokh +9 more
doaj +1 more source
Parathyroid Hormone-Related Protein Promotes Rat Stem Leydig Cell Differentiation
Frontiers in Physiology, 2017 The regulatory factors for stem Leydig cell development are largely unknown. Herein, we reported that parathyroid hormone-related protein (PTHrP) may be a factor to regulate this process.
Tiantian Song +11 more
doaj +1 more source
Activated effects of parathyroid hormone-related protein on human hepatic stellate cells. [PDF]
PLoS ONE, 2013 BACKGROUND & AIMS: After years of experiments and clinical studies, parathyroid hormone-related protein(PTHrP) has been shown to be a bone formation promoter that elicits rapid effects with limited adverse reaction.
Fen-Fen Liang +6 more
doaj +1 more source
Кубанский научный медицинский вестник, 2018 Aim. Based on the analysis of the scientific literature sources, the authors aimed to summarize and present the existing information about the role of parathyroid hormone-related protein (PTHrP) in pathogenesis of disorders of bladder contractile ...
V. I. Medvedev, A. N. Kurzanov
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) are two peptides that regulate mineral ion homeostasis, skeletal development, and bone turnover by activating parathyroid hormone 1 receptor (PTH1R). PTH1R signaling is of profound
Ping Lyu +7 more
doaj +1 more source
Positioning novel biologicals in CKD-mineral and bone disorders [PDF]
, 2017 Renal osteodystrophy (ROD), the histologic bone lesions of chronic kidney disease (CKD), is now included in a wider syndrome with laboratory abnormalities of mineral metabolism and extra-skeletal calcifications or CKD-mineral and bone disorders (CKD-MBD),
Covic, Adrian +5 more
core +1 more source
Kaposiform hemangioendothelioma with fatal income: Kasabach–Merritt phenomenon and hypercalcemia
Clinical Case Reports, 2022 Kaposiform hemangioendothelioma is a rare, borderline tumor that typically occurs during early childhood. Kasabach–Merritt phenomenon is a complication characterized by a consumptive coagulopathy resulting from the localized intravascular coagulation ...
Baklouti Massara +9 more
doaj +1 more source
PLoS ONE, 2016 Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients, but with an accelerated timeframe. This rapid effect on weight-bearing bones is also observed in astronauts who can lose up to 2%
A. Camirand +5 more
semanticscholar +1 more source