Interactions of sclerostin with FGF23, soluble klotho and vitamin D in renal transplantation [PDF]
, 2017 Relationships of Sclerostin, a bone anti-anabolic protein, with biomarkers of mineral bone disorders in chronic kidney disease are still unsettled, in particular in kidney transplant (KTR).
Farcomeni, Alessio +7 more
core +14 more sources
Frontiers in Cardiovascular Medicine, 2022 Parathyroid hormone is the main endocrine regulator of extracellular calcium and phosphorus levels. Secondary hyperparathyroidism–induced endothelial dysfunction may be related to calcium homeostasis disorders.
Shuhao Wang +10 more
doaj +1 more source
The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]
, 2013 The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves +3 more
core +1 more source
PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases. [PDF]
, 2018 Metastatic breast cancer (BrCa) is currently incurable despite great improvements in treatment of primary BrCa. The incidence of skeletal metastases in advanced BrCa occurs up to 70%.
Wang, Bin, Yang, Yanmei
core +2 more sources
PARATHYROID HORMONE-RELATED PROTEIN AND PROSTATE CANCER
Кубанский научный медицинский вестник, 2017 The survey presents the existing arguments and facts about the parathyroid hormone-related protein (PTHrP) and its role in pathophysiological and pathobio-chemical mechanisms that are related to onco-transformation of prostate.
V. L. MEDVEDEV +2 more
doaj +1 more source
Parathyroid hormone-related protein as predictor of urolithiasis disease development
Инновационная медицина Кубани, 2020 Background. The present article studies a possible role of parathyroid hormone-related protein (PTHrP) in urolithiasis pathogenesis.Aim. To consider PTHrP level as a predictor of the urolithiasis development.Material and Methods. We presented an analysis
A. A. Budanov +5 more
doaj +1 more source
PTHrP treatment of colon cancer cells promotes tumor associated-angiogenesis by the effect of VEGF [PDF]
, 2019 We showed that Parathyroid Hormone-related Peptide (PTHrP) induces proliferation, migration, survival and chemoresistance via MAPKs and PI3K/AKT pathways in colorectal cancer (CRC) cells.
Calvo, Natalia Graciela +4 more
core +1 more source
Parathyroid hormone-related protein in teleost fish [PDF]
General and Comparative Endocrinology, 2007 A brief description is given of the discovery of PTHrP and the roles of the peptide in mammalian physiology. Next, the occurrence of PTHrP in the earliest vertebrates, sharks, skates and fishes, is reviewed and the calciotropic functions of PTHrP are addressed more specifically in fishes.
Abbink, W., Flik, G.
openaire +4 more sources
Calcitriol-mediated hypercalcemia in a patient with bilateral adrenal non-Hodgkin's B-cell lymphoma case report [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2016 Calcitriol-mediated hypercalcemia is a frequent manifestation of hematological malignancies. However, there are a few reports of cases presenting with increased angiotensin-converting enzyme (ACE) level, which suggests a possible mechanism similar to ...
Ana Abaroa-Salvatierra +4 more
doaj +1 more source
Active vitamin D (1,25-dihydroxyvitamin D) and bone health in middle-aged and elderly men: the European male aging study (EMAS) [PDF]
, 2013 <p>Context: There is little information on the potential impact of serum 1,25-dihydroxyvitamin D [1,25(OH)2D] on bone health including turnover.</p> <p>Objective: The objective of the study was to determine the influence of 1,25(OH ...
Akhter +67 more
core +3 more sources