Pancreatic Adenocarcinoma Producing Parathyroid Hormone-Related Protein [PDF]
Case Reports in Oncological Medicine, 2017 A 48-year-old woman presented to our hospital with a 1-year history of a continuous high fever. She was diagnosed with metastatic pancreatic adenocarcinoma accompanied by leukocytosis without infection.
Reiko Yamada +12 more
doaj +5 more sources
Physiological roles of parathyroid hormone-related protein. [PDF]
Acta Biomed, 2019 Background: Parathyroid hormone related peptide (PTHrP) is widely expressed in a variety of normal fetal and adult tissues. Aim of work: Review of these normal physiologic functions of PTHrP in each of these tissues.
Lai NK, Martinez D.
europepmc +4 more sources
Role of Parathyroid Hormone and Parathyroid Hormone-Related Protein in Protein-Energy Malnutrition
Frontiers in Bioscience-Landmark, 2023 Parathyroid hormone (PTH) is an endocrine peptide found exclusively in the parathyroid glands, whereas parathyroid hormone-related protein (PTHrP) is expressed in a wide range of tissues and organs and exerts endocrine, paracrine, and autocrine actions ...
Praopilad Srisuwarn +1 more
doaj +2 more sources
The Parathyroid Hormone-Related Protein/Parathyroid Hormone 1 Receptor Axis in Adipose Tissue [PDF]
Biomolecules, 2021 Adipose tissue is an organ that shows great plasticity and is able to adapt to the conditions to which the body is subdued. It participates in the regulation of energetic homeostasis and has endocrine functions.
Adriana Izquierdo-Lahuerta
doaj +2 more sources
Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia. [PDF]
Cell Death Dis, 2021 Cancer cachexia is a metabolic disorder characterized by skeletal muscle wasting and white adipose tissue browning. Specific functions of several hormones, growth factors, and cytokines derived from tumors can trigger cachexia.
Hu W +13 more
europepmc +2 more sources
Parathyroid Hormone Related Protein (PTHrP)-Associated Molecular Signatures in Tissue Differentiation and Non-Tumoral Diseases [PDF]
Biology, 2023 Parathyroid-hormone-related protein (PTHrP) is encoded by the PTHLH gene which, via alternative promoter usage and splicing mechanisms, can give rise to at least three isoforms of 139, 141, and 173 amino acids with distinct C-terminals.
Mariangela Librizzi +4 more
doaj +2 more sources
Roles of Parathyroid Hormone-Related Protein (PTHrP) and Its Receptor (PTHR1) in Normal and Tumor Tissues: Focus on Their Roles in Osteosarcoma [PDF]
Frontiers in Veterinary Science, 2021 Osteosarcoma (OS) is the most common primary bone tumor and originates from bone forming mesenchymal cells and primarily affects children and adolescents.
Awf A. Al-Khan +6 more
doaj +2 more sources
A case of extrapulmonary tuberculosis in a patient with end-stage renal disease with elevated parathyroid hormone–related protein [PDF]
SAGE Open Medical Case Reports, 2020 The diagnosis of extrapulmonary tuberculosis in patients with end-stage renal disease can be challenging as the signs and symptoms are often non-specific.
Shreya Podder +2 more
doaj +2 more sources
Parathyroid hormone–related protein is a therapeutic target in idiopathic pulmonary fibrosis [PDF]
Signal Transduction and Targeted TherapyThe crosstalk between immune or alveolar epithelial cells and fibroblasts mediated by paracrine signaling molecules is associated with the pathogenesis of idiopathic pulmonary fibrosis (IPF).
Xue-Quan Fang +18 more
doaj +2 more sources
JBMR Plus, 2019 Intermittent administration of parathyroid hormone (PTH) stimulates skeletal remodeling and is a potent anabolic agent in bone. PTH‐related protein (PTHrP) is anabolic acting on the same PTH1 receptor and is in therapeutic use for osteoporosis.
Junro Yamashita, Laurie K McCauley
doaj +2 more sources