Results 41 to 50 of about 44,736 (232)

Parathyroid-hormone-related protein in sarcoidosis [PDF]

, 1998
Parathyroid-hormone-related protein (PTHrP) is the main mediator of the humoral hypercalcemia of malignancy. It is also detected in many normal adult and fetal tissues.
Hards, DK (15482495), Zhou, H (5397815), Martin, TJ (15482507), Doery, JCG (15482498), Hunter, AN (15482501), Zeimer, HJ (15482489), Grill, V (15482510), Slavin, J (15482492), Duffield, A (15482504), Timothy Greenaway (14737912)   +9 more
core  

Receptor activity-modifying protein modulation of parathyroid hormone-1 receptor function and signaling

Frontiers in Pharmacology
IntroductionReceptor activity-modifying proteins (RAMPs) are known to modulate the pharmacology and function of several G-protein-coupled receptors (GPCRs), including the parathyroid hormone 1 receptor (PTH1R).
Paris Avgoustou, Ameera B. A. Jailani, Aditya J. Desai, David J. Roberts, Ewan R. Lilley, Grant W. Stothard, Timothy M. Skerry, Gareth O. Richards   +7 more
doaj   +1 more source

Emerging Therapies for Osteoporosis [PDF]

Endocrinology and Metabolism, 2015
Although several effective therapies are available for the treatment of osteoporosis in postmenopausal women and older men, there remains a need for the development of even more effective and acceptable drugs.
Michael R. McClung
doaj   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Urinary excretion of parathyroid hormone-related protein correlates with renal function in control rats and rats with cisplatin nephrotoxicity [PDF]

, 2019
Parathyroid hormone-related protein (PTHrP) and its receptor are abundantly expressed throughout the renal parenchyma, where PTHrP exerts a modulatory action on renal function.
Olea Herrero, Nuria, Vélez Vélez, Esperanza, Esbrit, Pedro, Bosch, Ricardo J., Lázaro Fernández, Alberto, Ortega, Arantxa, Arenas, María Isabel, Tejedor Jorge, Alberto, Múñoz Moreno, Carmen, Moreno Gómez Toledano, Rafael   +9 more
core   +1 more source

A Case of Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D in Small Cell Lung Carcinoma Presenting as Symptomatic Hypercalcemia

Annals of Internal Medicine: Clinical Cases
A 75-year-old man presented with altered mental status in the setting of hypercalcemia. Computed tomography imaging showed a new right upper lobe lung lesion and extensive metastatic disease of the spine.
John Pueringer, Danich Qadir, James Love, Ryan Knodle, Michael Gianarakis, Gabriela Mendez, Frank Weinberg   +6 more
doaj   +1 more source

Ovarian cancer presenting with hypercalcemia: two cases with similar manifestations but different mechanisms

Cancer Biology & Medicine, 2018
Hypercalcemia presenting in ovarian cancer is uncommon in the clinic. Here, two cases of ovarian epithelial carcinoma that presented with severe hypercalcemia were reported, with a review of the literature.
Xuegong Ma, Yingmei Wang, Xuhong Zhang, Mengting Dong, Wen Yang, Fengxia Xue   +5 more
doaj   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

Parathyroid hormone-related protein: Hormone and cytokine [PDF]

, 1997
Parathyroid hormone-related protein: Hormone and ...
ED Williams (9893567), TJ Martin (15477635), JM Moseley (15876185)   +2 more
core  

Parathyroid hormone receptors in GtoPdb v.2021.3 [PDF]

, 2021
The parathyroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Parathyroid Hormone Receptors [49]) are class B G protein-coupled receptors.
Jueppner, H, Silve, C, Usdin, TB, Chorev, M, Vilardaga, J-P, Gardella, T, Martin, TJ, Hills, R, Bisello, A, Potts, Jr., JT, Friedman, PA, Nissenson, RA   +11 more
core   +1 more source