Results 91 to 100 of about 1,180,111 (402)

PTH-related protein and cancer [PDF]

, 2019
The clinical significance of parathyroid hormone-related protein in humoral hypercalcemia of malignancy was investigated by determining the serum parathyroid hormone-related protein concentrations in 167 normal subjects, 56 patients with hematologic ...
Bando, Hiroshi, Nakamura, Yuriko, Saito, Shiro, Shintani, Yasumi, Yokogoshi, Yutaka   +4 more
core  

Identification of signaling pathways in early mammary gland development by mouse genetics [PDF]

, 2004
The mammary gland develops as an appendage of the ectoderm. The prenatal stage of mammary development is hormone independent and is regulated by sequential and reciprocal signaling between the epithelium and the mesenchyme.
A Yang, AA Mailleux, AA Mill, C van Genderen, DL Chapman, GW Robinson, H van Bokhoven, J Foley, J Laurikkala, J Laurikkala, JJ Wysolmerski, JJ Wysolmerski, JM Veltmaat, JM Veltmaat, L Hennighausen, M Bamshad, ME Dunbar, OT Oftedal, T Andl, T Mustonen, TG Davenport   +20 more
core   +2 more sources

Biomimetic Microstructured Scaffold with Release of Re‐Modified Teriparatide for Osteoporotic Tendon‐to‐Bone Regeneration via Balancing Bone Homeostasis

Advanced Science, EarlyView.
This study develops RPTH by re‐modifying teriparatide and designs a biomimetic microstructured scaffold (BMRP) loaded with RPTH to address osteoporotic tendon‐to‐bone interface repair. The BMRP restores tissue architecture by balancing bone homeostasis and remodeling the microstructure, achieving functional recovery in an osteoporotic rotator cuff tear
Chengzhong Xu, Sijie Qiu, Zhigen Yuan, Chongyin Qiu, Wenyu Xu, Jialiang Guo, Gen Wen, Shuai Liu, Wenjuan Yan, Haibing Xu, Honghao Hou, Dehong Yang   +11 more
wiley   +1 more source

Interaction between serum FGF-23 and PTH in renal phosphate excretion, a case-control study in hypoparathyroid patients

BMC Nephrology, 2020
Background phosphate homeostasis is mediated through complex counter regulatory feed-back balance between parathyroid hormone, FGF-23 and 1,25(OH)2D. Both parathyroid hormone and FGF-23 regulate proximal tubular phosphate excretion through signaling on ...
Forough Saki, Seyed Reza Kassaee, Azita Salehifar, Gholam Hossein Ranjbar Omrani   +3 more
doaj   +1 more source

Modeling of mouse experiments suggests that optimal anti-hormonal treatment for breast cancer is diet-dependent [PDF]

arXiv, 2023
Estrogen receptor positive breast cancer is frequently treated with anti-hormonal treatment such as aromatase inhibitors (AI). Interestingly, a high body mass index has been shown to have a negative impact on AI efficacy, most likely due to disturbances in steroid metabolism and adipokine production.
arxiv  

Aggregation Induced Emissive Liquid Crystals‐Polymer Composite Membrane for Dual‐Channel Analysis of Parathyroid Hormone

Aggregate, EarlyView.
We introduce TPE‐PPE into liquid crystal (LC)‐based sensor, creating aggregation‐induced emissive LC (AIE‐LC) with high fluorescence sensitivity to LC molecules alignment for quantitative parathyroid hormone (PTH) analysis. Incorporating pre‐polymer and UV irradiation forms an AIE‐LC‐polymer film, lowering the detection limit due to an amorphous ...
Yingping Tong, Birong Wang, Dongyu Zhao, Min Li, Ben Zhong Tang   +4 more
wiley   +1 more source

Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death and cardiovascular disease in individuals with chronic kidney disease: a systematic review and meta-analysis.

Journal of the American Medical Association (JAMA), 2011
CONTEXT Clinical practice guidelines on the management of mineral and bone disorders due to chronic kidney disease recommend specific treatment target levels for serum phosphorus, parathyroid hormone, and calcium.
S. Palmer, A. Hayen, P. Macaskill, F. Pellegrini, J. Craig, G. Elder, G. Strippoli   +6 more
semanticscholar   +1 more source

Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection

Animal Models and Experimental Medicine, EarlyView.
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang, Yibai Xiong, Zhiqi Song, Yanhong Li, Ling Zhang, Chuan Qin   +5 more
wiley   +1 more source

PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases. [PDF]

, 2018
Metastatic breast cancer (BrCa) is currently incurable despite great improvements in treatment of primary BrCa. The incidence of skeletal metastases in advanced BrCa occurs up to 70%.
Wang, Bin, Yang, Yanmei
core   +2 more sources

Intermittent parathyroid hormone administration converts quiescent lining cells to active osteoblasts

Journal of Bone and Mineral Research, 2012
Intermittent administration of parathyroid hormone (PTH) increases bone mass, at least in part, by increasing the number of osteoblasts. One possible source of osteoblasts might be conversion of inactive lining cells to osteoblasts, and indirect evidence
S. W. Kim, P. Pajevic, M. Selig, K. J. Barry, J. Yang, C. S. Shin, W. Baek, Jung-Eun Kim, H. Kronenberg   +8 more
semanticscholar   +1 more source