Results 81 to 90 of about 1,155,277 (353)

The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone

Aging Cell, EarlyView.
scRNA‐seq analysis reveals age‐related changes in bone mesenchymal cells in male and female mice. Moreover, the comparison of aging and autophagy deficiency in bone mesenchymal cells shows overlap and suggests that age‐related decline in autophagy contributes to skeletal aging.
Melda Onal, Intawat Nookaew, Ana Resende‐Coelho, Olivia Reyes‐Castro, Adriana Marques‐Carvalho, Landon Gatrell, Alongkorn Kurilung, Alicen James, Aaron Warren, Ha‐Neui Kim, Jinhu Xiong, Charles A. O'Brien, Maria Almeida   +12 more
wiley   +1 more source

Protection of parathyroid function during thyroid surgery with a complete intermediate approach: a retrospective multicenter observational study

BMC Cancer
Background Iatrogenic injury of the parathyroid gland during thyroid surgery cannot be completely avoided. The lateral approach is the most commonly used surgical approach in traditional thyroid surgery, whereas the complete intermediate approach has ...
Jianming Yuan, Jianhua Gu, Min Ding, Xiaoli Jin, Dan Tan, Tingting Li, Wenjuan Xu, Shujing Wang, Yi Shen, Dongjie Shen, Dan Xu, Yaoxing Zeng, Guohui Xiao, Rongli Xie, Jian Fei   +14 more
doaj   +1 more source

Identification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism

Nature Communications, 2016
Hypoparathyroidism and osteoporosis can be treated with parathyroid hormone, but frequent injections are required. Here the authors develop a small-molecule agonist for the parathyroid hormone type I receptor that can be administered orally, and ...
Tatsuya Tamura, Hiroshi Noda, Eri Joyashiki, Maiko Hoshino, Tomoyuki Watanabe, Masahiko Kinosaki, Yoshikazu Nishimura, Tohru Esaki, Kotaro Ogawa, Taiji Miyake, Shinichi Arai, Masaru Shimizu, Hidetomo Kitamura, Haruhiko Sato, Yoshiki Kawabe   +14 more
doaj   +1 more source

Externalizing as a common genetic influence for a broad spectrum of substance use and behavioral conditions: A developmental perspective from the Avon Longitudinal Study of Parents and Children

Addiction, EarlyView.
Abstract Background and aims Recent large studies have established the genetic basis of several conceptually linked phenotypes of externalizing. Polygenic risk scores (PRSs) for these constructs are associated with a range of substance use and mental disorder phenotypes but have not been examined with both pharmacological and non‐pharmacological ...
Wei Q. Deng, Kyla Belisario, Amanda Doggett, Marie Pigeyre, Guillaume Pare, Marcus R. Munafò, James MacKillop   +6 more
wiley   +1 more source

Risk factors for hypocalcemia after total thyroidectomy: a narrative review [PDF]

PeerJ
Hypocalcemia is a frequent complication after total thyroidectomy and seriously affects patients’ postoperative quality of life and long-term prognosis.
Bohan Cao, Guangzhe Wu
doaj   +2 more sources

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

THE LOCUS OF ACTION OF THE PARATHYROID HORMONE: EXPERIMENTAL STUDIES WITH PARATHYROID EXTRACT ON NORMAL AND NEPHRECTOMIZED RATS 1 [PDF]

, 1943
Théodore H. Ingalls, Gordon Donaldson, Fuller Albright   +2 more
openalex   +1 more source

Aortic Pulse Wave Velocity and Extracellular Water Expansion in Hemodialysis Patients

Artificial Organs, EarlyView.
ABSTRACT Background Pulse wave velocity (PWV), a measurement of arterial stiffness, is a risk factor for cardiovascular mortality in hemodialysis patients. Debate continues as to whether PWV is increased by volume overload. As such, we reviewed the association between volume overload and PWV.
Roohi Chhabra, Andrew Davenport
wiley   +1 more source

Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis

Philippine Journal of Otolaryngology Head and Neck Surgery, 2015
Objective: To present a rare case of primary parathyroid carcinoma and discuss its clinical findings and management. Methods: Study Design:             Case Report Setting:                        Tertiary Government Hospital Patient:          
Ma. Melizza S. Villalon, Celso V. Ureta
doaj   +1 more source

Urinary Calcium and Phosphorus Excretion in Vitamin D‐Sufficient Preterm Infants: Establishing Age‐Specific Normative Data

Acta Paediatrica, EarlyView.
ABSTRACT Aim This study evaluated urinary calcium (Ca) and phosphorus (P) excretion in very low birth weight infants ( < 1500 g, VLBW) without severe morbidity, treated with methylxanthines. Methods Eighty‐one VLBW infants were analysed. Urinary Ca and P and their creatinine ratios were measured biweekly until day 56.
Tomas Matejek, Veronika Pokorna, Vojtech Drahy, Lenka Zaloudkova, Vladimir Palicka, Sylva Skalova   +5 more
wiley   +1 more source