Results 81 to 90 of about 506,992 (270)

Short-term recovery in patients suffering hypoparathyroid after thyroidectomy: a case control study

BMC Surgery, 2021
Background Postoperative hypoparathyroidism is the main reason for outpatient follow-up and long-term oral calcium and calcitriol treatment. Our study investigated the influencing factors and powerful predictors of short-term postoperative parathyroid ...
Duntao Su, Fada Xia, Wanze Huang, Zhejia Zhang, Ning Bai, Di Wang, Xin Liao, Xinying Li   +7 more
doaj   +1 more source

Bone Health and Aging in Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Klinefelter syndrome (KS) is typically diagnosed in young adults, but advances in prenatal testing have led to its recognition at a much earlier age. Conversely, diagnosis in late adulthood remains uncommon, but still occurs. Independently from the age at diagnosis, KS individuals now receive more accurate and tailored care management than in ...
Filippo Vignali, Daniele Renda Livraghi, Francesco Costantino, Sara De Vincentis, Vincenzo Rochira   +4 more
wiley   +1 more source

Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: The Extracellular Calcium Receptor and an Innovative Medical Approach to Control Secondary Hyperparathyroidism by Calcimimetics

Journal of Pharmacological Sciences, 2005
Circulating levels of calcium ion (Ca2+) are maintained within a narrow physiological range mainly by the action of parathyroid hormone (PTH) secreted from parathyroid cells.
Nobuo Nagano, Edward F. Nemeth
doaj   +1 more source

Teriparatide Topical Delivery Supports Osseointegration in Ovariectomized Rats Receiving Cafeteria Diet and Bisphosphonate: An In Vivo Experimental Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Background Postmenopausal osteoporosis associated with cafeteria diet and bisphosphonate therapy may impair peri‐implant bone repair. Therefore, strategies to enhance osseointegration are needed. Aim This study investigated whether teriparatide‐coated implant surfaces enhance osseointegration in a rodent model of estrogen deficiency (OVX) and ...
Ana Cláudia Ervolino da Silva, Fábio Roberto de Souza Batista, Jaqueline Suemi Hassumi, Naara Gabriela Monteiro, Marina Santos Fernandes, Luana Marotta Reis Vasconcellos, Gabriel Mulinari‐Santos, Reinhard Gruber, Paulo Noronha Lisboa‐Filho, Roberta Okamoto   +9 more
wiley   +1 more source

TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

Nature Communications, 2019
Parathyroid hormone (PTH) is used to treat osteoporosis, but its therapeutic mechanism remains unclear. Here, the authors show that Tgif1 is a PTH target gene, and that its deletion impairs the function of osteoblasts and PTH-induced bone formation in ...
Hiroaki Saito, Andreas Gasser, Simona Bolamperti, Miki Maeda, Levi Matthies, Katharina Jähn, Courtney L. Long, Hartmut Schlüter, Marcel Kwiatkowski, Vaibhav Saini, Paola Divieti Pajevic, Teresita Bellido, Andre J. van Wijnen, Khalid S. Mohammad, Theresa A. Guise, Hanna Taipaleenmäki, Eric Hesse   +16 more
doaj   +1 more source

Hypophosphataemia in adults: approach to diagnosis and management

Internal Medicine Journal, EarlyView.
Abstract Hypophosphataemia is a common electrolyte disorder which can have clinically significant consequences for bone, muscle, neurological and haematological function. Its causes range from transient transcellular shifts in hospitalised patients to chronic renal phosphate‐wasting disorders mediated by fibroblast growth factor 23 (FGF23).
Kajanan Parameshwaran, Mawson Wang, Kirtan Ganda   +2 more
wiley   +1 more source

SIKs control osteocyte responses to parathyroid hormone

Nature Communications, 2016
Parathyroid hormone (PTH) is an endogenous hormone and osteoporosis therapeutic that suppresses sclerostin activity. Here the authors develop SIK inhibitors as potential therapeutic tools and use them to show that PTH-cAMP signalling in osteocytes ...
Marc N. Wein, Yanke Liang, Olga Goransson, Thomas B. Sundberg, Jinhua Wang, Elizabeth A. Williams, Maureen J. O’Meara, Nicolas Govea, Belinda Beqo, Shigeki Nishimori, Kenichi Nagano, Daniel J. Brooks, Janaina S. Martins, Braden Corbin, Anthony Anselmo, Ruslan Sadreyev, Joy Y. Wu, Kei Sakamoto, Marc Foretz, Ramnik J. Xavier, Roland Baron, Mary L. Bouxsein, Thomas J. Gardella, Paola Divieti-Pajevic, Nathanael S. Gray, Henry M. Kronenberg   +25 more
doaj   +1 more source

Parathyroid Hormone in Osteoporosis Treatment

, 2002
Parathyroid hormone stimulates bone formation, prevents or reverses bone loss, increases bone mass, bone strength and provides protection against fractures.
İ. Özkul
core  

Association between impaired cold perception threshold and serum calcium in patients with type 2 diabetes mellitus

Journal of Diabetes Investigation, EarlyView.
Serum calcium independently influences cold perception threshold in type 2 diabetes mellitus. Serum calcium levels show a positive dose–response relationship with cold perception thresholds in DPN patients. Serum calcium correlates with thermal thresholds only in neuropathy patients, not in diabetes alone.
Yexuan Hao, Qiaoli Cui, Lang Qin, Wanwan Sun, Shiwei Zhou, Yuanpin Zhang, Hangping Zheng, Lijin Ji, Xiaoxia Liu, Shuo Zhang, Yanpei Cao, Yiming Li, Xiaoming Zhu   +12 more
wiley   +1 more source

Intraoperative secretion of intact parathyroid hormone and amino-terminal parathyroid hormone fragments from normal parathyroid glands associated with solitary parathyroid adenoma

, 1997
The nonadenomatous parathyroid glands associated with parathyroid adenoma in patients with primary hyperparathyroidism (pHPT) are assumed to exhibit suppressed secretion of parathyroid hormone (PTH).
Ahrén, B, Bergenfelz, A, Ahrén, B,, Bergenfelz, A,, Lund University.   +4 more
core   +2 more sources