Results 61 to 70 of about 57,490 (237)

Parathyroid hormone alleviates non-alcoholic liver steatosis via activating the hepatic cAMP/PKA/CREB pathway

open access: yesFrontiers in Endocrinology, 2022
Non-alcoholic fatty liver disease (NAFLD), hallmarked by liver steatosis, is becoming a global concern, but effective and safe drugs for NAFLD are still lacking at present.
Xu Feng   +7 more
doaj   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

open access: yesPediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil   +2 more
wiley   +1 more source

Gene therapy of hypoparathyroidism with TheraCyte-encapsulated stem cells [PDF]

open access: yes, 2010
The parathyroid hormone (PTH) (1-34) gene was inserted into a pcDNA3 promoter and E. coli competent cells were used to amplify the cDNA. C3H/10T1/2 stem cells were transfected with PTH (1-34) cDNA using Lipofectamine reagents.
Shun-Chen Huang   +5 more
core   +1 more source

Parathyroid Carcinoma and Ectopic Secretion of Parathyroid hormone [PDF]

open access: yes, 2021
: The most common causes of hypercalcemia are primary hyperparathyroidism (PHPT) and malignancy. Parathyroid carcinoma (PC), causing a severe PHPT, is the rarest parathyroid tumor.
Pardi E., Cetani F., Marcocci C.
core   +1 more source

Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone

open access: yesPediatric Investigation, EarlyView.
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu   +6 more
wiley   +1 more source

Parathyroid Hormone Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin [PDF]

open access: yesJournal of Investigative Dermatology, 2006
In developing organs, parathyroid hormone (PTH)/parathyroid hormone-related protein (PTHrP) receptor (PPR) signaling inhibits proliferation and differentiation of mesenchyme-derived cell types resulting in control of morphogenic events. Previous studies using PPR agonists and antagonists as well as transgenic overexpression of the PPR ligand PTHrP have
Godwin Diamond, A.   +7 more
openaire   +2 more sources

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

open access: yesVIEW, EarlyView.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin   +5 more
wiley   +1 more source

Parathyroid adenoma with rare severe pathological osteolytic lesion: a case report and literature review

open access: yesFrontiers in Oncology, 2023
Parathyroid adenomas are benign proliferative disorders of parathyroid glands. Patients typically exhibit hyperparathyroidism and elevated serum calcium levels due to elevated levels of parathyroid hormone (PTH).
Jia Chen   +3 more
doaj   +1 more source

Effect of antagonism of the parathyroid hormone (PTH)/PTH-related protein receptor on decidualization in rat uterus [PDF]

open access: yes, 1998
Effect of antagonism of the parathyroid hormone (PTH)/PTH-related protein receptor on decidualization in rat ...
ED Williams (9893567)   +4 more
core  

Parathyroid hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]

open access: yes, 2019
The parathyroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Parathyroid Hormone Receptors [47]) are family B G protein-coupled receptors.
Vilardaga, Jean-Pierre   +11 more
core   +2 more sources

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