Results 101 to 110 of about 396,713 (282)

Spectrum of Neurologic Complications in Chronic Lymphocytic Leukemia [PDF]

, 2012
Neurologic disease is believed to be an unusual complication during the course of chronic lymphocytic leukemia. Nevertheless, it has already been proven in autopsy series that the incidence of occult nervous system infiltration is much higher than was ...
Lopes Silva, R
core   +1 more source

Revisiting the Incidence of Hypercalcemia in Contemporary Diagnoses of Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Hypercalcemia is rarely observed in pediatric patients with cancer. However, rare cases of renal insufficiency and osteoporosis have been reported as severe consequences. Published literature focuses predominantly on hypercalcemia in pediatric hematologic malignancies, precluding causative associations with solid tumor disease ...
Felicia Y. Ho, Dajana Alku, Chalinee Monsereenusorn, Nan Chen, Wendy B. London, Allison F. O'Neill   +5 more
wiley   +1 more source

Synchronous primary papillary breast cancer, medullary thyroid carcinoma and neuroendocrine tumor in postmenopausal woman. [PDF]

, 2016
Multiple endocrine neoplasia are syndromes involving two or more endocrine tissues, often correlated to RET proto-oncogene mutations. We herein present the first reported case of a 57-years-old woman with three synchronous primary cancers of breast ...
DE IULIIS, Francesca, Lanza, Rosina, Lunardi, Gianluigi, Menghi, Antonello, Pecorella, Irene, Rossi, Lorena, Scarpa, Susanna, Sini, Valentina   +7 more
core  

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna, Amitava Mitra, Matthew L. Zierhut, Lilly East, Chandra Durairaj   +4 more
wiley   +1 more source

Near‐infrared fluorescence imaging with indocyanine green to identify parathyroid glands in two dogs undergoing bilateral modified intracapsular thyroidectomy

Veterinary Record Case Reports, EarlyView.
Abstract This case report describes one dog that underwent bilateral thyroidectomy and another that underwent unilateral thyroidectomy using near‐infrared fluorescence imaging with indocyanine green to visualise the external parathyroid glands to aid in their preservation.
Christine J. Ruffin, Brittany A. Carson, Mary A. McLoughlin, Laura E. Selmic   +3 more
wiley   +1 more source

Clinical suspicion and parathyroid carcinoma management

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Adequate management of parathyroid carcinoma apparently relates to the surgeon’s ability to identify it at the first operation.
Fabio Luiz de Menezes Montenegro, Marcos Roberto Tavares, Marcelo Doria Durazzo, Claudio Roberto Cernea, Anói Castro Cordeiro, Alberto Rosseti Ferraz   +5 more
doaj   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Spinal cord compression secondary to brown tumour in a patient on long-term haemodialysis: a case report. [PDF]

, 2009
Brown tumours may occur secondary to hyperparathyroidism in patients with chronic renal failure (CRF). Diagnosing a spinal brown tumour causing cord compression requires a high index of suspicion.
Luk, KD, Mak, KC, Wong, YW
core   +1 more source

Downregulation of Chromosome 19 miRNA Cluster and the Tumor‐Suppressive Role of miR‐517a‐3p in Choriocarcinoma

Cancer Science, EarlyView.
Chromosome 19 microRNA cluster was downregulated in choriocarcinoma compared with complete hydatidiform mole. miR‐517a‐3p reduced the proliferation, migration, and invasion abilities of choriocarcinoma cell lines. Downregulation of SRSF1, targeted by miR‐517a‐3p, suppressed the malignant potential of choriocarcinoma cell lines. ABSTRACT Choriocarcinoma
Yuki Nishiko, Kosuke Yoshida, Yuko Yasui, Akira Yokoi, Masami Kitagawa, Eri Inami, Masato Yoshihara, Kazumasa Mogi, Yukari Nagao, Satoshi Tamauchi, Nobuhisa Yoshikawa, Kimihiro Nishino, Eiko Yamamoto, Kaoru Niimi, Hiroaki Kajiyama   +14 more
wiley   +1 more source

Nutritional Deficiencies Following Bariatric Surgery: A Rapid Systematic Review of Case Reports of Vitamin and Micronutrient Deficiencies Presenting More Than Two Years Post‐Surgery

Clinical Obesity, EarlyView.
ABSTRACT Bariatric surgery is the most clinically‐ and cost‐effective intervention for severe obesity. However, without adequate follow‐up, it can lead to nutritional deficiencies. Patients require life‐long nutritional supplements and follow‐up to prevent nutritional deficiencies from developing.
Sophie Haughton, Sarah Gentry, Helen M. Parretti   +2 more
wiley   +1 more source