Results 101 to 110 of about 380,244 (316)

A Pleural Solitary Fibrous Tumor, Multiple Gastrointestinal Stromal Tumors, Moyamoya Disease, and Hyperparathyroidism in a Patient Associated with NF1 [PDF]

, 2015
Neurofibromatosis type 1 (NF1), also called von Recklinghausen’s disease, is a multisystemic disease caused by an alteration of the NF1 gene, a tumor suppressor located on the long arm of chromosome 17 (17q11.2). Loss of the gene function, due to a point
Ken Kodama, Masashi Takeda, Shigekazu Yokoyama, Shintaro Michishita, Yoko Yamamoto   +4 more
core   +3 more sources

Lactobacillus johnsonii Generates Cyclo(pro‐trp) and Promotes Intestinal Ca2+ Absorption to Alleviate CKD–SHPT

Advanced Science, EarlyView.
The mechanism map of how L.johnsonii generates cyclo(pro‐trp) to alleviate CKD–SHPT by promoting the expression of CaSR and TRPV4 in IECs, enhancing Ca2+ absorption, and negatively feedback inhibiting iPTH secretion. Abstract Patients with chronic kidney disease (CKD) are at a high risk of developing secondary hyperparathyroidism (SHPT), which may ...
Xiong Zeng, Lihua Sun, Huichao Xie, Shenhai Gong, Caibao Lu, Zhongwei Xu, Haidi Guan, Ben Han, Wei Wang, Zhengmin Zhang, Jieying Zhou, Shuai Wang, Yihui Chen, Weidong Xiao   +13 more
wiley   +1 more source

Large parathyroid adenomas: Potential mechanisms to reconcile adenoma size and disease phenotype

Frontiers in Endocrinology, 2023
Parathyroid adenomas weighing more than 3.5 g are reported variously as “atypical”, “large” or “giant” parathyroid adenomas. All such adenomas are rare variants accounting for no more than 1.5% of all parathyroid adenomas.
Arti Bhan, Shobana Athimulam, Poonam Kumari, Rimesh Pal, Sanjay Kumar Bhadada, Bernard C. Cook, Shijing Qiu, Sudhaker D. Rao, Sudhaker D. Rao   +8 more
doaj   +1 more source

Identification of NIBAN2‐Regulated RUNX2 Alternative Splicing Presents Novel Strategies for Antagonizing Osteoporosis

Advanced Science, EarlyView.
NIBAN2 interacts with the HNRNPU‐cored spliceosome complex and alters its components to regulate the alternative splicing of RUNX2, which ultimately cause an increase in functional RUNX2 (nuclear localization sequence complete) but a decrease in dysfunctional Runx2 (exon 6‐exclusive) isoforms to reinforce osteoblast differentiation.
Sheng Zhang, Zhiqiang Yang, Yuanlong Xie, Yufeng Zhang, Zhe Chen, Xuan Lv, Zhouming Deng, Zan Huang, Lin Cai, Renxiong Wei   +9 more
wiley   +1 more source

Adult Ectopic Cervical Thymic Tissue in relation to a Parathyroid Adenoma and a Papillary Thyroid Carcinoma: A Report of Two Cases

Case Reports in Otolaryngology, 2020
Ectopic cervical thymus is a rare congenital anomaly, which results because of the failure of complete descent of the thymus. They are incidental findings in the young and may disappear during the early years of life; however, they have rarely been ...
Vijay Shrawan Nijhawan, Roopali Sehrawat, Neeti Goyal, Manish Gupta   +3 more
doaj   +1 more source

Parathyroid carcinoma [PDF]

Vojnosanitetski Pregled, 2006
Background. Parathyroid carcinoma is the least frequent malignancy among endocrine tumors. In the most reported series of patients with primary hyperparathyroidism the incidence of carcinoma is less than 1%.
Filipović Aleksandar, Paunović Ivan, Savjak Dragutin, Živković Tamara   +3 more
doaj   +1 more source

Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery [PDF]

, 2016
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of intraoperative neuromonitoring (IONM) versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults ...
Abraha, Iosief, Arezzo, Alberto, Avenia, Nicola, Barczyñski, Marcin, Cirocchi, Roberto, D'ANDREA, Vito, Passera, Roberto, Randolph, Justus   +7 more
core   +1 more source

Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection

Animal Models and Experimental Medicine, EarlyView.
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang, Yibai Xiong, Zhiqi Song, Yanhong Li, Ling Zhang, Chuan Qin   +5 more
wiley   +1 more source

Genetics and Epigenetics of Parathyroid Carcinoma

Frontiers in Endocrinology, 2022
Parathyroid carcinoma (PC) is an extremely rare malignancy, accounting less than 1% of all parathyroid neoplasms, and an uncommon cause of primary hyperparathyroidism (PHPT), characterized by an excessive secretion of parathyroid hormone (PTH) and severe
Francesca Marini, Francesca Marini, Francesca Giusti, Gaia Palmini, Giuliano Perigli, Roberto Santoro, Maria Luisa Brandi   +6 more
doaj   +1 more source

Hierarchical Phenotyping and Graph Modeling of Spatial Architecture in Lymphoid Neoplasms [PDF]

arXiv, 2021
The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the first to hybridize local and global graph methods to profile orchestration and interaction of cellular components.
arxiv