Results 131 to 140 of about 381,589 (317)

Prognosis and Phenotypes of Advanced Head and Neck Carcinoma Associated With Hypercalcemia

Head &Neck, EarlyView.
ABSTRACT Purpose Hypercalcemia is the most common metabolic disorder in cancer, affecting 10%–20% of patients with advanced malignancies, including squamous cell carcinoma of the head and neck (HNSCC), though its prognostic significance remains poorly studied.
Elodie Mamou, Paul Gougis, Baptiste Abbar, Jean‐philippe Spano, Laetitia Morardet, Aurore Vozy   +5 more
wiley   +1 more source

Galectin-3. The impact on the clinical management of patients with thyroid nodules and future perspectives [PDF]

, 2018
Galectins (S-type lectins) are an evolutionarily-conserved family of lectin molecules, which can be expressed intracellularly and in the extracellular matrix, as well.
Bartolazzi, Armando, D’Alessandria, Calogero, Sciacchitano, Salvatore   +2 more
core   +2 more sources

Instant Intraoperative Histopathological Assessment of Fresh Parathyroid Tissue: Higher Harmonic Generation Microscopy as a Potential Alternative to Frozen Section

Head &Neck, EarlyView.
ABSTRACT Background Hypoparathyroidism is a complication associated with significant morbidity and results from inadvertent removal of the parathyroid during thyroid surgery. Therefore, intra‐operative identification of parathyroid tissue is essential to minimize the risk of hypoparathyroidism.
P. M. Rodriguez Schaap, S. van den Bosch, S. Spies, S. van Eeden, E. J. M. Nieveen van Dijkum, M. L. Groot, A. F. Engelsman   +6 more
wiley   +1 more source

Multiple ectopic parathyroid adenomas

São Paulo Medical Journal
CONTEXT: Primary hyperparathyroidism is the most common cause of hypercalcemia in unselected patients. The ectopic gland locations should be known for appropriate surgical exploration and for avoiding subsequent re-exploration that would represent higher
Rogério Aparecido Dedivitis, André Vicente Guimarães, Gustavo Bastos de Goes Pontes   +2 more
doaj   +1 more source

No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]

, 1933
G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P., Karl, M., Reincke, Martin, Travis, W.   +3 more
core  

Brown tumor of the jaw after pregnancy and lactation in a MEN1 patient [PDF]

, 2016
Skeletal manifestations of primary hyperparathyroidism (pHPT) include brown tumors (BT), which are osteoclastic focal lesions often localized in the jaws.
Alberola Ferranti, Margarita, Casteràs, Anna, Caubet, Enric, Darder, Lídia, Hueto Madrid, Juan Antonio, Mesa Manteca, Jordi, Universitat Autònoma de Barcelona. Departament de Cirurgia, Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques, Universitat Autònoma de Barcelona. Departament de Medicina, Zafon, Carles   +9 more
core   +2 more sources

Preoperative Vitamin D Supplementation to Reduce Hypocalcemia Following Total Thyroidectomy: Systematic Review and Meta‐Analysis of Randomized Clinical Trials

Head &Neck, EarlyView.
ABSTRACT Objective This study aims to determine whether preoperative supplementation of vitamin D reduces the incidence of hypocalcemia following total thyroidectomy. Methods Conducted in conformity with the PRISMA statement, a systematic review and meta‐analysis of randomized clinical trials (RCT) was performed assessing postoperative hypocalcemia and
Luca Canali, Gian Marco Pace, Marika D. Russell, Francesca Gaino, Luca Malvezzi, Gherardo Mazziotti, Andrea Lania, Giuseppe Spriano, Michael Mannstadt, Gregory W. Randolph, Giuseppe Mercante   +10 more
wiley   +1 more source

A Case of Advanced Renal Cell Carcinoma With Concomitant Development of Multiple Endocrine Neoplasia Type 1 That Affected Treatment Progress With Immunotherapy

IJU Case Reports, EarlyView.
ABSTRACT Introduction Hypercalcemia is a poor prognostic factor in advanced cancer. Case Presentation A patient with advanced clear cell renal carcinoma with hypercalcemia was treated with nivolumab+ipilimumab combination therapy. Treatment was discontinued after 4 months due to renal dysfunction.
Masataka Abe, Yoshiyuki Miyaji, Seitetsu Sugiyama, Kiwami Tsurui, Hirofumi Morinaka, Mikako Kaifu, Hiroyuki Kadoya, Wataru Saito, Koji Yoshida, Kazumasa Komura   +9 more
wiley   +1 more source

The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]

, 2014
G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin, Ivan, Michael E, Kaur, Gurvinder, Oh, Michael C, Oh, Taemin, Parsa, Andrew T, Safaee, Michael, Sayegh, Eli T, Sun, Matthew Z   +8 more
core   +2 more sources

Systematic in‐hospital screening and treatment for osteoporosis in a geriatric population with hip fractures

Journal of Hospital Medicine, EarlyView.
Abstract Background Low‐trauma fractures of the hip signify osteoporosis and increase the risk of a second fracture. However, screening for secondary osteoporosis and initiating osteoporosis treatment can be challenging in a geriatric population.
Jeppe B. Rosenbæk, Line B. Dalgaard, Anne Grauballe, Stella J. Wilfred, Mikkel W. Ibsen, Lene R. Madsen   +5 more
wiley   +1 more source