Results 51 to 60 of about 26,209 (245)

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Clinicopathological insights into primary hyperparathyroidism: a comprehensive single-center retrospective study

Endokrynologia Polska
INTRODUCTION: Primary hyperparathyroidism (PHPT) is caused by excessive hormone secretion from one or more parathyroid glands. Based on their morphological and immunophenotypic characteristics, parathyroid glands can be considered as neuroendocrine ...
Dorota Anna Brodowska-Kania, Marek Saracyn, Natalia Osial, Adrianna Mróz, Bartłomiej Grala, Olga Remyzovska, Adam Daniel Durma, Michał Wiłkojć, Piotr Kowalewski, Piotr Zięcina, Maciej Kołodziej, Grzegorz Kamiński   +11 more
doaj   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Tertiary hyperparathyroidism masking an atypical parathyroid tumor

Clinical Case Reports
Key Clinical Message Atypical parathyroid tumors represent a group of parathyroid neoplasms of uncertain malignant potential. In view of preoperative diagnostic difficulties, suspicious features for malignancy may guide the surgeon to perform a radical ...
Styliani Laskou, Ismini Kountouri, Eleni Paschou, Christos Topalidis, Paraskevi Axi, Georgios Petrakis, Christoforos Kosmidis, Konstantinos Sapalidis   +7 more
doaj   +1 more source

Adult Ectopic Cervical Thymic Tissue in relation to a Parathyroid Adenoma and a Papillary Thyroid Carcinoma: A Report of Two Cases

Case Reports in Otolaryngology, 2020
Ectopic cervical thymus is a rare congenital anomaly, which results because of the failure of complete descent of the thymus. They are incidental findings in the young and may disappear during the early years of life; however, they have rarely been ...
Vijay Shrawan Nijhawan, Roopali Sehrawat, Neeti Goyal, Manish Gupta   +3 more
doaj   +1 more source

P53 mutations in human adrenocortical neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Allolio, B., Chrousos, G. P., Karl, M., Linehan, M., Mastorakis, G., Reincke, Martin, Travis, W.   +6 more
core  

Parathyroid Retrospective Analysis of Neoplasms Incidence (pTRANI Study): An Italian Multicenter Study on Parathyroid Carcinoma and Atypical Parathyroid Tumour

Journal of Clinical Medicine, 2023
Background: Parathyroid cancer (PC) is a rare sporadic or hereditary malignancy whose histologic features were redefined with the 2022 WHO classification. A total of 24 Italian institutions designed this multicenter study to specify PC incidence, describe its clinical, functional, and imaging characteristics and improve its differentiation from the ...
Gurrado A., Pasculli A., Avenia N., Bellantone R., Boniardi M., Boschin I. M., Calo P. G., Camandona M., Cavallaro G., Cianchi F., Conzo G., Dandrea V., De Crea C., De Pasquale L., Del Rio P., Di Meo G., Dionigi G., Dobrinja C., Docimo G., Fama F., Galimberti A., Giacomelli L., Graceffa G., Iacobone M., Innaro N., Lombardi C. P., Materazzi G., Medas F., Mullineris B., Oragano L., Palestini N., Perigli G., Pezzolla A., Prete F. P., Raffaelli M., Renzulli G., Rosato L., Scerrino G., Sgaramella L. I., Sorrenti S., Testini C., Veroux M., Gasparri G., Testini M., Andreani S., Bonati E., Canu G. L., Clemente L., Dabbicco D., Frattini F., Freddi M., Gervasi R., Giliberti G., Lavermicocca W., Massara A., Melcarne R., Palagi S., Patrone R., Pennestri F., Poli E., Rossi L., Sisto G., Toma A., Torresan F., Vallon G.   +64 more
openaire   +7 more sources

Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Do Not Arrest Bone Loss in Patients With Rheumatoid Arthritis: A Long‐Term Multicenter Observational Study

Arthritis &Rheumatology, EarlyView.
Objective Osteoporosis causes fractures that further increase the disease burden of rheumatoid arthritis (RA); however, osteoporosis treatment rates remain low. Although several studies have reported that biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) can prevent or improve osteoporosis in RA, our large‐scale, real ...
Takafumi Aritomi, Koshiro Sonomoto, Shingo Nakayamada, Hiroaki Tanaka, Atsushi Nagayasu, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Naoaki Ohkubo, Yasuyuki Todoroki, Yurie Satoh‐Kanda, Masanobu Ueno, Ryuichiro Kanda, Yuya Fujita, Masashi Funada, Hidenori Sakai, Satsuki Matsunaga, Hiroaki Tanaka, Masayuki Shinojima, Hiroki Kawamura, Kazuki Takahashi, Miyabi Ando, Kazuki Haru, Yusuke Miyazaki, Kentaro Hanami, Masao Nawata, Shunsuke Fukuyo, Keisuke Nakatsuka, Mikiko Tokunaga, Kazuyoshi Saito, Yoshiya Tanaka   +30 more
wiley   +1 more source

Carcinoma of the parathyroid gland: a case report

Liječnički vjesnik, 2023
Carcinoma of the parathyroid gland causes 0.005% of all malignancies. Although the etiology remains unknown, possible contributing factors include neck radiation, chronic secondary hyperparathyroidism due to kidney failure, and vitamin D deficiencies. It
Matea Kostić, Andrea Kostić, Maja Baretić   +2 more
doaj   +1 more source