Results 61 to 70 of about 21,463 (235)

Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Do Not Arrest Bone Loss in Patients With Rheumatoid Arthritis: A Long‐Term Multicenter Observational Study

Arthritis &Rheumatology, EarlyView.
Objective Osteoporosis causes fractures that further increase the disease burden of rheumatoid arthritis (RA); however, osteoporosis treatment rates remain low. Although several studies have reported that biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) can prevent or improve osteoporosis in RA, our large‐scale, real ...
Takafumi Aritomi, Koshiro Sonomoto, Shingo Nakayamada, Hiroaki Tanaka, Atsushi Nagayasu, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Naoaki Ohkubo, Yasuyuki Todoroki, Yurie Satoh‐Kanda, Masanobu Ueno, Ryuichiro Kanda, Yuya Fujita, Masashi Funada, Hidenori Sakai, Satsuki Matsunaga, Hiroaki Tanaka, Masayuki Shinojima, Hiroki Kawamura, Kazuki Takahashi, Miyabi Ando, Kazuki Haru, Yusuke Miyazaki, Kentaro Hanami, Masao Nawata, Shunsuke Fukuyo, Keisuke Nakatsuka, Mikiko Tokunaga, Kazuyoshi Saito, Yoshiya Tanaka   +30 more
wiley   +1 more source

Impaired glucose metabolism and other metabolic disorders in patients with primary hyperparathyroidism

Сахарный диабет, 2021
The clinical picture of primary hyperparathyroidism (PHPT) which caused by parathyroid neoplasms often includes metabolic syndrome leading to the development of cardiovascular diseases.
Ekaterina E. Bibik, [Anna K. Eremkina, Julia A. Krupinova, Natalia V. Klementieva, Ekaterina A. Dobreva, Natalia G. Mokrysheva   +5 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Mice deleted for cell division cycle 73 gene develop parathyroid and uterine tumours:model for the hyperparathyroidism-jaw tumour syndrome [PDF]

, 2017
The hyperparathyroidism-jaw tumour (HPT-JT) syndrome is an autosomal dominant disorder characterized by occurrence of parathyroid tumours, often atypical adenomas and carcinomas, ossifying jaw fibromas, renal tumours and uterine benign and malignant ...
B O Williams, Jeyabalan, J, Harding, B, Bowl, Michael R., Newey, P J, Walls, GV, Bradley, KJ, Harding, Brian, K J Bradley, A A C Reed, Bradley, K J, Thakker, RV, Reed, AAC, Teh, BT, Manek, Sanjiv, M R Bowl, Lines, K E, Chen, J, Manek, S, K E Lines, Wang, P, P Wang, R V Thakker, Reed, A A C, B Harding, M Stevenson, Thakker, Rajesh V., Bowl, MR, P J Newey, Wang, P. Z., B T Teh, Jeyabalan, Jeshmi, Stevenson, M, G V Walls, J Chen, Newey, PJ, Lines, KE, Stevenson, Mark, J Jeyabalan, Williams, B O, Teh, B. T., Walls, Gerard V., S Manek, Williams, BO   +43 more
core   +1 more source

Carcinoma of the parathyroid gland: a case report

Liječnički vjesnik, 2023
Carcinoma of the parathyroid gland causes 0.005% of all malignancies. Although the etiology remains unknown, possible contributing factors include neck radiation, chronic secondary hyperparathyroidism due to kidney failure, and vitamin D deficiencies. It
Matea Kostić, Andrea Kostić, Maja Baretić   +2 more
doaj   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype [PDF]

, 2013
PubMed ID: 23555276This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
OCCHI, GIANLUCA, Pellegata, NS, Pardi E, Giampaolo Trivellin, Franco Mantero (392960), Cetani, F., Carla Scaroni, Sidarovich V, Carla Scaroni (392961), CIATO, DENIS, Sidarovich, V, Ciato, D., Franco Mantero, Denis Ciato (392953), Regazzo, D, Ferasin, S, Viktoryia Sidarovich, Quattrone, A., Giampaolo Trivellin (106006), Pardi, E, MANTERO, FRANCO, Francesca Boaretto (392952), Bobisse S, Pellegata NS, Denis Ciato, SCARONI, CARLA, Korbonits M, Márta Korbonits (59514), Opocher, G., Sara Bobisse (392954), Regazzo, D., Gianluca Occhi (38330), Daniela Regazzo, Viktoryia Sidarovich (392959), Francesca Boaretto, Daniela Regazzo (392951), REGAZZO, DANIELA, Korbonits, M., Filomena Cetani, Scaroni, C, Ciato, D, Natalia S Pellegata, Mantero, F, Elena Pardi (392957), Pellegata, N.S., Giuseppe Opocher (260071), Giuseppe Opocher, Scaroni, C., Alessandro Quattrone (220189), Cetani F, Bobisse, S, Boaretto, F, Mantero, F., Trivellin G, Quattrone, A, Elena Pardi, Márta Korbonits, Sergio Ferasin, Trivellin, G, Sidarovich, V., Filomena Cetani (392956), BOARETTO, FRANCESCA, Occhi, G., Natalia S. Pellegata (392958), Bobisse, S., Sara Bobisse, Trivellin, G., Boaretto, F., Sergio Ferasin (392955), Gianluca Occhi, Alessandro Quattrone, OPOCHER, GIUSEPPE, FERASIN, SERGIO, Opocher, G, Ferasin, S., Korbonits, M, Pardi, E., Occhi, G, Quattrone A, Cetani, F   +79 more
core   +1 more source

Genetics and Epigenetics of Parathyroid Carcinoma

Frontiers in Endocrinology, 2022
Parathyroid carcinoma (PC) is an extremely rare malignancy, accounting less than 1% of all parathyroid neoplasms, and an uncommon cause of primary hyperparathyroidism (PHPT), characterized by an excessive secretion of parathyroid hormone (PTH) and severe
Francesca Marini, Francesca Marini, Francesca Giusti, Gaia Palmini, Giuliano Perigli, Roberto Santoro, Maria Luisa Brandi   +6 more
doaj   +1 more source

Evaluation of the metabolism properties of choline kinase alpha in neoplasms of the parathyroid glands. A pilot study [PDF]

, 2019
BACKGROUND: Primary hyperparathyroidism (PHPT) is a widespread endocrine disease characterized by excessive production of parathyroid hormone (PTH) due to parathyroid gland hyperplasia (PGH) or tumor lesions (adenoma or cancer of the parathyroid gland ...
Julia A. Krupinova, Mikhail B. Dolgushin, Sergey N. Kuznetsov, Irina V. Kryukova, Natalia G. Mokrysheva, Iya A. Voronkova, Akgul A. Odzharova, Larisa E. Gurevch   +7 more
core   +2 more sources

Parathyroid carcinoma: an unusual presentation of a rare neoplasm

German medical science : GMS e-journal, 2017
Das Nebenschilddrüsenkarzinom ist eine extrem seltene, bösartige endokrine Neoplasie, deren Diagnose und Behandlung eine große Herausforderung darstellen. Klinisch wird die Erkrankung früher in Patienten mit Hyperparathyreoidismus mit Zeichen von schwerer Hyperkalzämie entdeckt.
Shruti, S, Siraj, F
openaire   +3 more sources