Results 11 to 20 of about 28,550 (262)

Specificity Evaluation of a Polyprotein-Based ELISA Designed for the Detection of Paratuberculosis in Multiple Species. [PDF]

Vet Med Int
Paratuberculosis (PTB) is a disease affecting ruminant animals. The etiological agent, Mycobacterium avium subspecies PTB (Map), is a short, Gram‐positive, acid‐fast bacillus. Due to the nature of PTB, diagnosis often occurs at advanced stages of the disease, following the onset of clinical symptoms and prior dissemination of the agent. The specificity
Moyano RD, Colombatti Olivieri MA, Basconez González M, Garrido JM, Juste RA, Alonso MN.   +5 more
europepmc   +2 more sources

Viewpoint: The Use of Antimycobacterial (Anti-MAP) Therapies in the Treatment of Active Luminal Crohn's Disease. [PDF]

JGH Open
ABSTRACT Mycobacterium avium subspecies paratuberculosis (MAP) as the infectious cause of Crohn's disease and the use of antimycobacterial (anti‐MAP) therapies in its treatment remain topics of controversy. A major limitation accepting this view is that irrefutable evidence that MAP causes Crohn's disease—the demonstration that long‐term remission ...
Pavli P, Gibson PR.
europepmc   +2 more sources

Seroprevalence study of paratuberculosis: Johne's disease, a neglected infection in dairy herds in Apulia (southern Italy). [PDF]

Vet Rec Open
Abstract Introduction Paratuberculosis (PTB) is a disease caused by Mycobacterium avium subsp. paratuberculosis (MAP). In Italy, voluntary PTB control plans have been implemented; nonetheless, so far, data on the prevalence of PTB in dairy herds are fragmented and incomplete, especially in the south of the country.
Galgano M, Messina D, D'Amico F, Sposato A, Razzuoli E, Mrenoshki D, Trisolini C, Caldarola G, Beverelli M, Ridolfi D, Bulzacchelli C, Giannico A, Parisi A, Tateo A, Pratelli A, Buonavoglia D.   +15 more
europepmc   +2 more sources

Paratuberculosis [PDF]

Clinical Microbiology Reviews, 1994
Paratuberculosis (Johne's disease) is a chronic, wasting, widespread mycobacteriosis of ruminants. It involves extensive mycobacterial shedding, which accounts for the high contagiousness, and ends with a fatal enteritis. Decreases in weight, milk production, and fertility produce severe economic loss.
Cocito, C, Gilot, P, Coene, M, de Kesel, M, Poupart, P, Vannuffel, P   +5 more
openaire   +5 more sources

Evaluating the Effects of 60°C Heating for 90 Min on Bacterial Pathogen Viability and IgG Concentration in Bovine Colostrum. [PDF]

Vet Med Sci
Heating bovine colostrum at 60°C for up to 90 min eliminates key pathogens, including Escherichia coli, Salmonella Enteritidis, Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium, while preserving IgG levels. This protocol ensures microbial safety and colostrum quality, offering a practical solution for dairy herd health ...
Moazeni M, Rasooli A, Nouri M, Ghorbanpoor M, Mosavari N, Zakian A.   +5 more
europepmc   +2 more sources

Killing of Mycobacterium avium subspecies paratuberculosis within macrophages

BMC Microbiology, 2002
Background Mycobacterium avium subspecies paratuberculosis (M. paratuberculosis) is a facultative intracellular pathogen that resides within host macrophages during infection of ruminant animals. We examined survival of M.
Stabel Judith R, Bannantine John P
doaj   +1 more source

A murine oral model for Mycobacterium avium subsp. paratuberculosis infection and immunomodulation with Lactobacillus casei ATCC 334

Frontiers in Cellular and Infection Microbiology, 2014
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) the causative agent of Johne’s disease, is one of the most serious infectious diseases in dairy cattle worldwide.
Meagan A. Cooney, James L Steele, Howard eSteinberg, Adel M Talaat   +3 more
doaj   +1 more source

Protection efficacy of Argentinian isolates of Mycobacterium avium subsp. paratuberculosis with different genotypes and virulence in a murine model [PDF]

, 2018
Paratuberculosis is a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (Map). The disease causes economic losses and, therefore, it is imperative to follow proper control strategies, which should include an effective vaccine. Several
Alvarado Pinedo, María Fiorella, Colombatti Olivieri, María Alejandra, Delgado, Fernando Oscar, Gravisaco, Maria Jose Federica, Mon, Maria Laura, Moyano, Roberto Damian, Romano, Maria Isabel, Santangelo, María de la Paz, Travería, Gabriel Eduardo   +8 more
core   +1 more source

Vaccination against paratuberculosis

Expert Review of Vaccines, 2008
Johne's disease, or paratuberculosis, is a chronic granulomatous enteritis in ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP) affecting principally cattle, sheep and goats. Primarily, there are two clinical signs: cachexia and chronic diarrhea (less common in goats and sheep).
Valérie, Rosseels, Kris, Huygen
openaire   +2 more sources

A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. [PDF]

, 2009
BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes.
Bull, TJ, Hermon-Taylor, J, Hinds, J, Linedale, R   +3 more
core   +3 more sources