Specificity Evaluation of a Polyprotein-Based ELISA Designed for the Detection of Paratuberculosis in Multiple Species. [PDF]
Paratuberculosis (PTB) is a disease affecting ruminant animals. The etiological agent, Mycobacterium avium subspecies PTB (Map), is a short, Gram‐positive, acid‐fast bacillus. Due to the nature of PTB, diagnosis often occurs at advanced stages of the disease, following the onset of clinical symptoms and prior dissemination of the agent. The specificity
Moyano RD +5 more
europepmc +2 more sources
Viewpoint: The Use of Antimycobacterial (Anti-MAP) Therapies in the Treatment of Active Luminal Crohn's Disease. [PDF]
ABSTRACT Mycobacterium avium subspecies paratuberculosis (MAP) as the infectious cause of Crohn's disease and the use of antimycobacterial (anti‐MAP) therapies in its treatment remain topics of controversy. A major limitation accepting this view is that irrefutable evidence that MAP causes Crohn's disease—the demonstration that long‐term remission ...
Pavli P, Gibson PR.
europepmc +2 more sources
Seroprevalence study of paratuberculosis: Johne's disease, a neglected infection in dairy herds in Apulia (southern Italy). [PDF]
Abstract Introduction Paratuberculosis (PTB) is a disease caused by Mycobacterium avium subsp. paratuberculosis (MAP). In Italy, voluntary PTB control plans have been implemented; nonetheless, so far, data on the prevalence of PTB in dairy herds are fragmented and incomplete, especially in the south of the country.
Galgano M +15 more
europepmc +2 more sources
Novel single nucleotide polymorphism-based assay for genotyping Mycobacterium avium subsp. paratuberculosis [PDF]
Typing of Mycobacterium avium subspecies paratuberculosis strains presents a challenge, since they are genetically monomorphic and traditional molecular techniques have limited discriminatory power.
Bryant, Josephine +6 more
core +2 more sources
Limitations of variable number of tandem repeat typing identified through whole genome sequencing of Mycobacterium avium subsp. paratuberculosis on a national and herd level [PDF]
Background: Mycobacterium avium subsp. paratuberculosis (MAP), the causative bacterium of Johne’s disease in dairy cattle, is widespread in the Canadian dairy industry and has significant economic and animal welfare implications. An understanding of the
Ahlstrom, Christina +13 more
core +1 more source
High Molecular Diversity of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> in Germany Revealed by Multitarget Genotyping. [PDF]
Möbius P, Price-Carter M, Köhler H.
europepmc +3 more sources
Molecular biology techniques as a tool for detection and characterisation of Mycobacterium avium subsp. paratuberculosis [PDF]
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) is the causative agent of paratuberculosis, also known as Johne’s disease, a chronic intestinal infection in cattle and other ruminants.
Englund, Stina
core
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto +14 more
wiley +1 more source
No difference in paratuberculosis seroprevalence between organic and conventional dairy herds in the Netherlands [PDF]
Purpose. Paratuberculosis or Johne’s disease in cattle is considered to play a role in the pathogenesis of Crohn’s disease in humans. Whether organic production may influence the prevalence of paratuberculosis in dairy herds was not known until now and ...
Kijlstra, Prof.Dr. A.
core +2 more sources
Complex responses to movement-based disease control: when livestock trading helps [PDF]
Livestock disease controls are often linked to movements between farms, for example, via quarantine and pre- or post-movement testing. Designing effective controls, therefore, benefits from accurate assessment of herd-to-herd transmission.
Hutchings, Michael R. +4 more
core +3 more sources

