A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. [PDF]
BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes.
Hermon-Taylor, J +11 more
core +1 more source
Exploring the Zoonotic Potential of Mycobacterium avium Subspecies paratuberculosis through Comparative Genomics. [PDF]
A comparative genomics approach was utilised to compare the genomes of Mycobacterium avium subspecies paratuberculosis (MAP) isolated from early onset paediatric Crohn's disease (CD) patients as well as Johne's diseased animals.
Michalski Wojtek P. +32 more
core +1 more source
Diagnosis of paratuberculosis in fresh and paraffin embedded samples by histopathology, PCR and immunohistochemistry techniques [PDF]
Mycobacterium avium subsp. paratuberculosis (Map) is the causative agent of paratuberculosis, also called Johne’s disease. Affected ruminants show emaciation, decreased milk production, oedema, anaemia and infertility.
R. Kheirandish +4 more
doaj +1 more source
A meta-analysis of the effect of dose and age at exposure on shedding of Mycobacterium avium subspecies paratuberculosis (MAP) in experimentally infected calves and cows [PDF]
A meta-analysis was performed using all published and one unpublished long-term infection-challenge experiments to quantify the age- and dose-dependence of early and late shedding of Mycobacterium avium subsp. paratuberculosis (MAP) in cattle. There were
Schukken, Y. H. +7 more
core +1 more source
Risk management of paratuberculosis in dairy herds
Risk management of paratuberculosis (Johne's disease) in a dairy herd requires an assessment of the likelihood of paratuberculosis occurring in the herd, the economic impact of paratuberculosis on the herd and an evaluation of measures that can be taken ...
Weber Maarten F
doaj +1 more source
Raw milk and dairy products are usually considered the major sources of Mycobacterium avium subsp. paratuberculosis (MAP) exposure for humans. During the production process of mozzarella cheese, as well as of other pasta-filata cheeses made with ...
Filippo Barsi +12 more
doaj +1 more source
Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains [PDF]
BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks
Richard Linedale +15 more
core +1 more source
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) the causative agent of Johne’s disease, is one of the most serious infectious diseases in dairy cattle worldwide.
Meagan A. Cooney +3 more
doaj +1 more source
Killing of
Background Mycobacterium avium subspecies paratuberculosis (M. paratuberculosis) is a facultative intracellular pathogen that resides within host macrophages during infection of ruminant animals. We examined survival of M.
Stabel Judith R, Bannantine John P
doaj +1 more source
Peripheral IFN-ɣ Production after Blood Stimulation with Different Mycobacterial Antigens in Goats Vaccinated against Paratuberculosis [PDF]
[EN] Vaccination can be an efficient method for the control of paratuberculosis in ruminants. However, the official tuberculosis control tests cross-interfere with the animals vaccinated against paratuberculosis. In order to test and compare new antigens
Ferreras Estrada, María Del Carmen +5 more
core +2 more sources

