PLoS ONE, 2007 BackgroundMycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including primates. Humans are exposed through milk and from sources of environmental contamination.
Tim J Bull +6 more
doaj +2 more sources
, 2021 Paratuberculosis or Johne's disease is an incurable disease of ruminants caused by a bacterium called Mycobacterium aviun subspecies paratuberculosis or MAP. This bacterium causes a granulomatous enteritis, which manifests with persistent or recurrent diarrhea that does not respond to antibiotic treatment. It is distributed worldwide and affects cattle,
Mata Masis, María
openaire +2 more sources
Specificity Evaluation of a Polyprotein-Based ELISA Designed for the Detection of Paratuberculosis in Multiple Species. [PDF]
Vet Med IntParatuberculosis (PTB) is a disease affecting ruminant animals. The etiological agent, Mycobacterium avium subspecies PTB (Map), is a short, Gram‐positive, acid‐fast bacillus. Due to the nature of PTB, diagnosis often occurs at advanced stages of the disease, following the onset of clinical symptoms and prior dissemination of the agent. The specificity
Moyano RD +5 more
europepmc +2 more sources
Effect of paratuberculosis vaccination before and after oral experimental infection with <i>Mycobacterium avium</i> subspecies <i>paratuberculosis</i> in goats. [PDF]
Vet Q24 páginas, 10 figuras, 2 tablas.Vaccination against paratuberculosis, before or after infection with Mycobacterium avium subsp. paratuberculosis (Map), could affect the progression of paratuberculosis, the development of lesions, the peripheral and ...
Royo M +4 more
europepmc +2 more sources
Viewpoint: The Use of Antimycobacterial (Anti-MAP) Therapies in the Treatment of Active Luminal Crohn's Disease. [PDF]
JGH OpenABSTRACT Mycobacterium avium subspecies paratuberculosis (MAP) as the infectious cause of Crohn's disease and the use of antimycobacterial (anti‐MAP) therapies in its treatment remain topics of controversy. A major limitation accepting this view is that irrefutable evidence that MAP causes Crohn's disease—the demonstration that long‐term remission ...
Pavli P, Gibson PR.
europepmc +2 more sources
Seroprevalence study of paratuberculosis: Johne's disease, a neglected infection in dairy herds in Apulia (southern Italy). [PDF]
Vet Rec OpenAbstract Introduction Paratuberculosis (PTB) is a disease caused by Mycobacterium avium subsp. paratuberculosis (MAP). In Italy, voluntary PTB control plans have been implemented; nonetheless, so far, data on the prevalence of PTB in dairy herds are fragmented and incomplete, especially in the south of the country.
Galgano M +15 more
europepmc +2 more sources
Peripheral IFN-ɣ Production after Blood Stimulation with Different Mycobacterial Antigens in Goats Vaccinated against Paratuberculosis [PDF]
, 2023 [EN] Vaccination can be an efficient method for the control of paratuberculosis in ruminants. However, the official tuberculosis control tests cross-interfere with the animals vaccinated against paratuberculosis. In order to test and compare new antigens
Ferreras Estrada, María Del Carmen +5 more
core +2 more sources
Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains [PDF]
, 2013 BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks
Richard Linedale +15 more
core +1 more source
A meta-analysis of the effect of dose and age at exposure on shedding of Mycobacterium avium subspecies paratuberculosis (MAP) in experimentally infected calves and cows [PDF]
, 2011 A meta-analysis was performed using all published and one unpublished long-term infection-challenge experiments to quantify the age- and dose-dependence of early and late shedding of Mycobacterium avium subsp. paratuberculosis (MAP) in cattle. There were
Schukken, Y. H. +7 more
core +1 more source
Exploring the Zoonotic Potential of Mycobacterium avium Subspecies paratuberculosis through Comparative Genomics. [PDF]
, 2011 A comparative genomics approach was utilised to compare the genomes of Mycobacterium avium subspecies paratuberculosis (MAP) isolated from early onset paediatric Crohn's disease (CD) patients as well as Johne's diseased animals.
Michalski Wojtek P. +32 more
core +1 more source