Results 41 to 50 of about 8,127 (184)

Detection of paratuberculosis in dairy cows from southern Brazil

open access: yesPesquisa Veterinária Brasileira, 2023
: Bovine paratuberculosis causes chronic, incurable diarrhea and weight loss, resulting in decreased cattle production. The disease is caused by Mycobacterium avium subsp.
Diorges H. Setim   +7 more
doaj   +1 more source

Bayesian Estimation of True Prevalence and Associated Risk Factors for Leptospira spp. Among Slaughterhouse Workers and Slaughtered Cattle in the Bahr El Ghazal Region of South Sudan

open access: yesZoonoses and Public Health, Volume 73, Issue 3, Page 181-190, May 2026.
ABSTRACT Introduction Leptospirosis is a major but under‐reported zoonotic disease, and epidemiological data from South Sudan remain limited. This study estimated the true prevalence of Leptospira spp. exposure and identified associated risk factors among slaughterhouse workers and slaughtered cattle in Western Bahr El Ghazal. Methods A cross‐sectional
David Onafruo   +11 more
wiley   +1 more source

Active surveillance of paratuberculosis in Alpine-dwelling red deer (Cervus elaphus)

open access: yesFrontiers in Veterinary Science
Paratuberculosis (Johne’s disease) is a globally widespread infectious disease affecting domestic and wild ruminants, caused by Mycobacterium avium subsp. paratuberculosis (MAP).
Anita Filippi   +18 more
doaj   +1 more source

Serial and Parallel Testing Strategies for Johne's Disease: Effects on Milk Production Traits and Milk Income on New Zealand Dairy Cattle

open access: yesNew Zealand Journal of Agricultural Research, Volume 69, Issue 2, April 2026.
The suboptimal accuracy of current diagnostic tests necessitates alternative testing strategies to improve the detection of Johne's disease. We studied parallel and serial testing strategies to quantify the association between milk production and Johne's disease status. For this, two commercial Johne's disease Enzyme‐Linked Immunosorbent Assay, ELISAs,
Venkatesh K. M.   +5 more
wiley   +1 more source

Deep Learning‐Enabled Engineering of a Hyper‐Stable and Soluble MPB70‐83 Antigen for Sensitive Bovine Tuberculosis Surveillance

open access: yesMicrobial Biotechnology, Volume 19, Issue 4, April 2026.
Schematic representation of the research workflow for the efficient diagnosis of bovine tuberculosis employing peptide fusion proteins. ABSTRACT Bovine tuberculosis (bTB) diagnostics are frequently hindered by the structural instability and insolubility of recombinant multi‐epitope proteins in prokaryotic expression systems.
Wen‐Hao Wang   +15 more
wiley   +1 more source

Comparative Transcriptomic Analysis of Human Macrophages During Mycobacterium avium Versus Mycobacterium tuberculosis Infection

open access: yesMolecular Microbiology, Volume 125, Issue 3, Page 185-202, March 2026.
Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç   +4 more
wiley   +1 more source

A novel multi-antigen virally vectored vaccine against Mycobacterium avium subspecies paratuberculosis.

open access: yesPLoS ONE, 2007
BackgroundMycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including primates. Humans are exposed through milk and from sources of environmental contamination.
Tim J Bull   +6 more
doaj   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

The Relationship Between Immunopathology and Body Condition of Mixed‐Age Ewes

open access: yesNew Zealand Journal of Agricultural Research, Volume 69, Issue 1, February 2026.
Ill thrift in ewes, characterised by less than desirable body condition, is a multifactorial condition often attributed to nutritional deficits, though immunopathological factors may also play a role. This study investigated associations between body condition scores (BCS) and immunopathological states in 120 mixed‐age ewes grazing pasture over 4 ...
Melissa N. Hempstead   +15 more
wiley   +1 more source

Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2010
Samples from intestines, liver, and lymph nodes were collected from a dairy steer with clinical suspicion of paratuberculosis. The samples were processed for histologic examination with hematoxylin-eosin and Zihel-Neelsen (ZN) staining for the detection ...
A.B.F Rodrigues   +6 more
doaj   +1 more source

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