Comparative functional genomics and the bovine macrophage response to strains of the Mycobacterium genus [PDF]
Mycobacterial infections are major causes of morbidity and mortality in cattle and are also potential zoonotic agents with implications for human health.
Gordon, SV+5 more
core +1 more source
A Hypothesis for Explaining the Geographical Distribution of Crohn’s Disease
The etiology of Crohn’s disease (CD) remains unknown, although there is epidemiological evidence supporting an environmental influence. Recent molecular techniques, including polymerase chain reaction, have renewed interest in a possible etiological role
Cyrus P Tamboli
doaj +1 more source
Serological and epidemiological investigation of subspecies paratuberculosis in bovines in Pakistan [PDF]
Objective This study aimed to investigate the prevalence of paratuberculosis in cattle and buffaloes at twelve public dairy farms in Punjab, Pakistan. Methods A total of 2,181 more than two-year-old animals (1,242 cattle and 939 buffaloes) were tested by
Aziz ur Rehman+10 more
doaj +1 more source
Mycobacterium avium Subspecies paratuberculosis Recombinant Proteins Modulate Antimycobacterial Functions of Bovine Macrophages. [PDF]
It has been shown that Mycobacterium avium subspecies paratuberculosis (M. paratuberculosis) activates the Mitogen Activated Protein Kinase (MAPK) p38 pathway, yet it is unclear which components of M.
John P Bannantine+4 more
doaj +1 more source
Zinc transporter 8 and MAP3865c homologous epitopes are recognized at T1D onset in Sardinian children [PDF]
Our group has recently demonstrated that Mycobacterium avium subspecies paratuberculosis (MAP) infection significantly associates with T1D in Sardinian adult patients.
Carlo Ripoli+5 more
core +3 more sources
Transmission of Paratuberculosis
The causative organism of paratuberculosis, Mycobacterium paratuberculosis, inhabits the intestinal tract and mesenteric lymph nodes of infected cows. While paratuberculosis has generally been regarded as an enteric infection, there is now evidence that the organism can disseminate to extra-intestinal sites such as uterus, supramammary lymph nodes ...
openaire +4 more sources
Molecular biology techniques as a tool for detection and characterisation of Mycobacterium avium subsp. paratuberculosis [PDF]
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) is the causative agent of paratuberculosis, also known as Johne’s disease, a chronic intestinal infection in cattle and other ruminants.
Englund, Stina
core
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto+14 more
wiley +1 more source
No difference in paratuberculosis seroprevalence between organic and conventional dairy herds in the Netherlands [PDF]
Purpose. Paratuberculosis or Johne’s disease in cattle is considered to play a role in the pathogenesis of Crohn’s disease in humans. Whether organic production may influence the prevalence of paratuberculosis in dairy herds was not known until now and ...
Kijlstra, Prof.Dr. A.
core +2 more sources
Description of a novel adhesin of Mycobacterium avium subsp. paratuberculosis [PDF]
The binding and ingestion of Mycobacterium avium subsp. paratuberculosis (MAP) by host cells are fibronectin (FN) dependent. In several species of mycobacteria, a specific family of proteins allows the attachment and internalization of these bacteria by ...
Echeverria Valencia, Gabriela Fernanda+8 more
core +1 more source