Results 31 to 40 of about 186,333,048 (184)

Identification of sex hormone-binding globulin in the human hypothalamus [PDF]

open access: yes, 2005
Gonadal steroids are known to influence hypothalamic functions through both genomic and non-genomic pathways. Sex hormone-binding globulin ( SHBG) may act by a non-genomic mechanism independent of classical steroid receptors.
Caldwell, Jack D.   +7 more
core   +1 more source

Neonatal overfeeding attenuates acute central pro-inflammatory effects of short-term high fat diet

open access: yesFrontiers in Neuroscience, 2015
Neonatal obesity predisposes individuals to obesity throughout life. In rats, neonatal overfeeding also leads to early accelerated weight gain that persists into adulthood.
Guohui eCai   +10 more
doaj   +1 more source

Cellular Localization of Orexin 1 Receptor in Human Hypothalamus and Morphological Analysis of Neurons Expressing the Receptor

open access: yesBiomolecules, 2023
The orexin system is related to food behavior, energy balance, wakefulness and the reward system. It consists of the neuropeptides orexin A and B, and their receptors, orexin 1 receptor (OX1R) and orexin 2 receptor (OX2R). OX1R has selective affinity for
Konstantina Vraka   +11 more
doaj   +1 more source

Neuroanatomical characterisation of the expression of the lipodystrophy and motor-neuropathy gene Bscl2 in adult mouse brain.

open access: yesPLoS ONE, 2012
The endoplasmic reticulum localised protein seipin, encoded by the gene Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2), serves a critical but poorly defined function in the physiology of both adipose and neural tissue. In humans, BSCL2 loss-of-
Alastair S Garfield   +5 more
doaj   +1 more source

Location-specific activation of the paraventricular nucleus of the hypothalamus by localized inflammation [PDF]

open access: yesBrain, Behavior, and Immunity, 2010
The existence of an immunological homunculus has been proposed, but evidence for location-specific response of the central nervous system to immunological stimulation is lacking. In this study, we show that inflammation induced by injection of casein into one of the causes c-fos expression in the paraventricular nucleus of the hypothalamus (PVN) in an ...
Natalya, Belevych   +4 more
openaire   +2 more sources

Novel unconditioned prosocial behavior in prairie voles (Microtus ochrogaster) as a model for empathy

open access: yesBMC Research Notes, 2018
Objective In this study, empathy is quantified using a novel social test. Empathy and prosocial behavior are linked to the expression of oxytocin in humans and rodent models.
Lucas A. Stetzik   +3 more
doaj   +1 more source

Activity of neurones in the paraventricular nucleus of the hypothalamus and its control

open access: yesThe Journal of Physiology, 1966
1. Activity of the paraventricular nucleus neurones was recorded by micro‐electrodes during resting conditions and while various osmotic, chemical, direct and indirect neural stimuli were applied. This activity was correlated with evidence of oxytocin release by recording milk ejection responses.2.
C M, Brooks   +3 more
openaire   +3 more sources

Ultradian calcium rhythms in the paraventricular nucleus and subparaventricular zone in the hypothalamus [PDF]

open access: yesProceedings of the National Academy of Sciences, 2018
Significance Despite that the various functions in mammals fluctuate in the ultradian fashion, the origin and mechanism of the rhythm are largely unknown. In this study, we found synchronous ultradian calcium rhythms in the hypothalamic paraventricular nucleus (PVN), subparaventricular zone (SPZ), and suprachiasmatic nucleus (SCN ...
Wu, Yu-Er   +5 more
openaire   +3 more sources

Cardiovascular Function of the Paraventricular Nucleus of the Hypothalamus

open access: yesNeurosignals, 1995
Recent evidence is showing that the paraventricular nucleus (PVN) of the hypothalamus plays a key role in autonomic regulation. Studies by the author of the PVN neurones that project to the spinal cord are reviewed. These neurones are inhibited by arterial baroreceptors and excited or inhibited by pulmonary/cardiac vagal afferents.
openaire   +2 more sources

An enhanced expression of hypothalamic neuronal nitric oxide synthase in a rat model of simulated transport stress

open access: yesBMC Veterinary Research, 2019
Background Transport stress not only causes physiological changes but also induces behavioral responses, including anxiety-like and depression-like behavioral responses in animals.
Jia Wang   +4 more
doaj   +1 more source

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