Results 91 to 100 of about 33,382 (248)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Elisabetta Ježec, The Lexicon. An Introduction

open access: yesLexis: Journal in English Lexicology, 2019
Cathy Parc
doaj   +1 more source

G-PARC: Graph-Physics Aware Recurrent Convolutional neural networks for spatiotemporal dynamics on unstructured meshes

open access: yesScientific Reports
Physics-aware recurrent convolutional networks (PARC) have demonstrated strong performance in predicting nonlinear spatiotemporal dynamics by embedding differential operators directly into the computational graph of a neural network. However, pixel-based
Jack T. Beerman   +8 more
doaj   +1 more source

Comparative species distribution model framework for marine conservation and its application to loggerhead turtles in the Mediterranean

open access: yesConservation Biology, EarlyView.
Abstract Modeling species distributions in dynamic pelagic environments remains challenging, particularly for wide‐ranging and highly mobile species when there is limited guidance on model performance. This limitation constrains the effective use of species distribution models (SDMs) in marine conservation, where robust and transferable predictions are
E. Pasanisi   +32 more
wiley   +1 more source

Detection of quinolone-resistance mutations of parC gene in clinical isolates of Acinetobacter baumannii in Iran

open access: yesJournal of Research in Medical Sciences, 2014
Background: The purpose of this study was to screen of parC gene mutations in clinical isolates of Acinetobacter baumannii from intensive care units (ICUs) of Alzahra Hospital, Isfahan, Iran. Materials and Methods: Seventy isolates of A.
Bahareh Vakili   +3 more
doaj  

Extensibility governs the flow-induced alignment of polymers and rod-like colloids

open access: yesPhysical Review Research
Polymers and rod-like colloids (PaRC) adopt a favorable orientation under sufficiently strong flows. However, how the flow kinematics affect the alignment of such nanostructures according to their extensibility remains unclear.
Vincenzo Calabrese   +5 more
doaj   +1 more source

Mitigating the human link in emerging reptile fungal pathogen transmission

open access: yesConservation Biology, EarlyView.
Abstract Handling wild reptiles is common among amateur herpetology enthusiasts, professional researchers, social media influencers, and photographers. However, the potential for these interactions to spread diseases that threaten wild reptiles remains underappreciated.
Patrick S. Champagne   +4 more
wiley   +1 more source

Mapping of Former Strategies and Future Needs for Regulatory Prevention of Skin Sensitization: Cosmetic Products

open access: yesContact Dermatitis, EarlyView.
This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen   +7 more
wiley   +1 more source

Phenotypes and clinical outcomes in children with moderate‐to‐severe atopic dermatitis across diverse ancestries: a Spanish multicenter observational study and cluster analysis (AD‐SKINS Project)

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Atopic dermatitis (AD) has a highly variable clinical phenotype and ancestry can contribute to this heterogeneity. This study aims to identify clinical phenotypes of AD in children from diverse ancestry groups, evaluate clinical outcomes and response to treatment, and define phenotypic clusters with potential relevance.
Eugeni Prat‐Colilles   +21 more
wiley   +1 more source

The Importance of the Larval Parasitoid Actia interrupta (Diptera: Tachinidae) in Low Density Eastern Spruce Budworm Populations

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
Actia interrupta is an important larval tachinid parasitoid during low‐density populations of the eastern spruce budworm. In the late 1980s during the outbreak collapse, Meteorus trachynotus was initially the most important species, but was replaced by A. interrupta. Host patch size and density had no impact on the parasitism rates by A.
Véronique Martel   +2 more
wiley   +1 more source

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