Results 191 to 200 of about 53,892 (273)

Customer demand-driven low-carbon vehicles combined strategy and route optimisation integrated decision. [PDF]

open access: yesSci Rep, 2021
Liu H   +7 more
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

Optimisation of Last-Mile Parcel Delivery: Leveraging Crowdsourcing and Mobile Parcel Lockers

open access: yes
In urban areas, the challenges posed by last-mile delivery, which contribute to congestion and create logistical obstacles in business to customer (B2C) e-commerce, require sustainable and innovative solutions. This study suggests addressing this issue through crowdsourced parcel delivery using mobile parcel lockers.
Akbarpour, Mina   +2 more
openaire   +1 more source

Flat Bands Induced by Non‐Collinear Antiferromagnetism in CoBi2Te4

open access: yesAdvanced Science, EarlyView.
Flat bands emerge at the edges of intrinsically non‐collinear antiferromagnetic CoBi2Te4 two‐septuple layers through the interplay of spin–orbit coupling–driven band inversion and non‐collinear antiferromagnetism, uncovering a previously unexplored mechanism for flat‐band formation and opening new opportunities for strongly correlated quantum states ...
Ziyuan Zhao   +4 more
wiley   +1 more source

Unveiling the Ultralow Thermal Conductivity of Hybrid Perovskites

open access: yesAdvanced Science, EarlyView.
In hybrid perovskites, thermal energy flows through lattice vibrations of the framework (48%–65%) and organic molecules (35%–52%). When the disorder introduced by organic molecules is excluded, the temperature dependence of the vibrational thermal conductivity results from the lattice framework transits from ∼T0 to ∼T−1, and the value doubles at room ...
Qinqin He   +3 more
wiley   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

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